2차 및 3차 병원에서 분리된 균종들에 대한 항생제 감수성 = Antibiotic Susceptibility Test Against Several Bacterial Species Isolated from Secondary and Tertiary Hospital

다국어 초록 (Multilingual Abstract)

Objective : This study was carried out to compare the isolation rates of antibiotic resistant bacteria between the secondary hospital (B) and the tertiary hospital (P).
Materials and Methods : The 3,813 strains of bacteria were isolated from various specimens in the B and P hospital. Antibiotic susceptibility test was performed by disc diffusion method with ampicillin, carbenicillin, cefamandole, cefotaxime, ciprofloxacin, gentamicin, imipenem, ampicillin-sulbactam, trimethoprim-sulfamethoxazole, cephalothin, ceftazidime, piperacillin, amikacin, tobramycin, vancomycin, erythromycin, oxacillin, penicillin, and clindamycin.
Result : The major pathogenic bacteria with high isolation rate in both the B and the P hospital were E.coli, K.pneumoniae, S.aureus, and P.aeruginosa. The isolation rate of E.coli, a resistance to cefamandole, ciprofloxacin, gentamicin, ampicillin-sulbactam, and trimethoprim-sulfamethoxazole was attentively higher in the P hospital than in the B hosiptal. The isolation rate of K. pneumoniae, a resistance to ampicillin, carbenicillin, ciprofloxacin, gentamicin, ampicillin-sulbactam, and trimethoprim-sulfamethoxazole was attentively high in the P hospital. The isolation rate of S.aureus, a resistance to ampicillin-sulbactam, cephalothin, trimethoprim-sulfamethoxazole, oxacillin, and penicillin was attentively high in the P hospital. The isolation rate of P.aeruginosa, a resistance to gentamicin, imipenem, and amikacin was attentively high in the P hospital. The isolation rate of S.epidermidis, a resistance to ampicillin-sulbactam, cephalothin and trimethoprim-sulfamethoxazole was attentively high in the P hospital. The isolation rate of P.mirabilis, a resistance to cefamandole, cefotaxime, gentamicin, trimethoprim-sulfamethoxazole and cephalothin was attentively high in the P hospital.
Conclusion : The isolation frequency of the antibiotic resistant bacteria from the P hospital was higher than that of the B hospital. These results demonstrate that the isolation frequency of the antibiotic resistant bacteria from both B and P hospital showed some difference according to the kinds of antibiotics and bacterial strains. These results attracted our attention to use of antibiotics, and it is urgent to arrange a countermeasure against the abuse of the antibiotic agents.