Temperature is crucial for single cell and tissue related research because enzyme activity is affected by the temperature and anaerobic metabolism is induced by enzymes in cell. So it needs to keep optimum temperature in order to control these enzymes...
Temperature is crucial for single cell and tissue related research because enzyme activity is affected by the temperature and anaerobic metabolism is induced by enzymes in cell. So it needs to keep optimum temperature in order to control these enzymes and also maintain original state. Here, we develop a temperature controllable medical chilling device with thermoelectric cooling (TEC) module. We optimize the device design by heat transfer analysis and providing the optimal shape of waterways and flow rate condition of coolants. Through these changes, the device reaches the target temperature more quickly and maintains it more efficiently. We integrate a customized heat exchanger in order to facilitate heat transfer from the TEC to coolant. Also, the optimized coolant flow rate is explored so that the power consumption in the thermoelectric module and the pump can be minimized. We demonstrate the performance of a heat-exchanger embedded medical chilling device in hair follicle cell implants in collaboration with a dermatologist due to its easy quantification.