지구성 운동시 혈청 CPK, LDH, LDH Isoenzyme 및 젖산 반응 = The Effects of Submaximal Exercise on the Blood Lactate, CPK, Total LDH Isoenzymes in Middle-aged Males

다국어 초록 (Multilingual Abstract)

This study was done to compare the response of serum CPK, LDH and LDH isoenzyme to submaximal exercise in middle aged trained and sedentary male and evaluate the effect of regular physical activity on the enzyme response during exercise. The subjects were 14 men participating regularly in physical activity (amateur soccer team) and 14 sedentary men.
All subjects were asked to perform bicycle ergometer exercise at the level of 70% HRmax during 40 minutes. The blood samples were drawn from each subject's antecubital vein by catheter all five times (pre, 10min., 20min, 40min, post 30min) and analyzed LDH, CPK, LDH isoenzyme and lactate.
The results obtained from data analysis were as follows ;
1. The peak level of lactate concentration appeared at 20min-exercise in both groups and sedentary group showed significantly higher level of lactate than exercise group (4.27 : 4.92mM, p<05)
2. Serum CPK in exercise group significantly increased at 10min and 20min exercise (p<01-0.05), but thereafter decreased down to pre-level at 40min exercise and after 30min-recovery. On the other hand, in sedentary group serum CPK consistantly increased during all exercise time course and maintained high level after 30min-recovery compared to pre-level. Therefore, the changes of serum CPK level at 40 min exercise and 30min recovery showed significant difference between two groups.
3. Although serum LDH showed similar changes with serum CPK in both groups, there was no significant difference between exercise group and sedentary group.
4. The heart specific LDH isoenzyme decreased consistantly during exercise, while the muscle specific LDH isoenzyme, especially, LDH_5 increased according to time course in both groups. Although these changes appeared more remarkably in sedentary group than in exercise group, there was no significant difference between both groups.

목차 (Table of Contents)

• Ⅰ. 서론
• Ⅱ. 연구 방법
• 1. 피험자
• 2. 실험 절차
• 3. 자료분석
• Ⅲ. 결과
• Ⅳ. 논의
• Ⅴ. 결론