<P>Herein, we report a rapid in vitro assay of amyloid beta anti-aggregation reagents using gold nanoparticles as nucleation cores and optical reporters. Based on the colorimetric responses observed with the naked eye, effective anti-aggregation...
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https://www.riss.kr/link?id=A107434207
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2017
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SCI,SCIE,SCOPUS
학술저널
4449-4452(4쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P>Herein, we report a rapid in vitro assay of amyloid beta anti-aggregation reagents using gold nanoparticles as nucleation cores and optical reporters. Based on the colorimetric responses observed with the naked eye, effective anti-aggregation...
<P>Herein, we report a rapid in vitro assay of amyloid beta anti-aggregation reagents using gold nanoparticles as nucleation cores and optical reporters. Based on the colorimetric responses observed with the naked eye, effective anti-aggregation reagents were rapidly (<15 min) distinguished. For these reagents, conventional methods showed fewer amyloid b aggregates and an increased viability of neuroblastoma cells after treatment. We envision that our proposed method will facilitate the discovery of efficient drug components for the treatment of Alzheimer's disease.</P>
An endoplasmic reticulum-selective ratiometric fluorescent probe for imaging a copper pool