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      키토올리고당과 토종꿀 혼합조성물의 항균 및 면역 활성 = Antibacterial and Immune Activities of Mixture of Oligochitosan and Herbal Honey

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      https://www.riss.kr/link?id=A82601206

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      다국어 초록 (Multilingual Abstract)

      Chitosan is an attractive biomaterial for wound care because of its biocompatibility and intrinsic hemostatic and antimicrobial properties. Honey has been used since ancient times for the treatment of some respiratory diseases and for the healing of s...

      Chitosan is an attractive biomaterial for wound care because of its biocompatibility and intrinsic hemostatic and antimicrobial properties. Honey has been used since ancient times for the treatment of some respiratory diseases and for the healing of skin wounds. In this study, we investigated the effect of mixture of oligochitosan and herbal honey(chito/H) on atopic dermatitis treatment. The effect of chito/H was analyzed by clinical skin features of atopic dermatitis skin lesions, measuring the serum lgE, and investigated skin surface using an optical microscope. The scores of skin symptom level and the serum IgE were decreased after treatment with chito/H compared with durg as a control group. These results suggest that the chito/H may be an alternative substance for the treatment of atopic dermatitis.

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      참고문헌 (Reference)

      1 성현철, "아토피피부염에서 임상적 중증도에 따른 알레르기 검사소견" 대한피부과학회 44 (44): 1051-1057, 2006

      2 성현철, "아토피피부염에서 임상적 중증도에 따른 알레르기 검사소견" 대한피부과학회 44 (44): 1051-1057, 2006

      3 T. Kakinuma, "Thymus and activation-regulated chemokinein atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity" 107 : 535-541, 2001

      4 S.K. Gupta, "Therapeutic efficacy of honey in infected wounds in buffaloes" 62 : 521-523, 1992

      5 S. Romagnani, "The role of lymphocytes in allergic disease" 105 : 399-408, 2000

      6 R.A.A. Muzzarelli, "The molecular weight of chitosans studied by laser light-scattering" 164 : 433-442, 1987

      7 F. Rousset, "Shifts in interleukin-4 and interferon-gamma production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis" 87 : 58-69, 1991

      8 Stein, R. T., "Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years" 354 : 541-545, 1999

      9 P. Ernst, "Relative Scarcity of Asthmaand Atopy among Rural Adolescents Raised on a Farm" 161 : 1563-, 2000

      10 Knorr, D., "Recovery and utilization of chitin and chitosan in food processing waste management" 45 (45): 1991

      1 성현철, "아토피피부염에서 임상적 중증도에 따른 알레르기 검사소견" 대한피부과학회 44 (44): 1051-1057, 2006

      2 성현철, "아토피피부염에서 임상적 중증도에 따른 알레르기 검사소견" 대한피부과학회 44 (44): 1051-1057, 2006

      3 T. Kakinuma, "Thymus and activation-regulated chemokinein atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity" 107 : 535-541, 2001

      4 S.K. Gupta, "Therapeutic efficacy of honey in infected wounds in buffaloes" 62 : 521-523, 1992

      5 S. Romagnani, "The role of lymphocytes in allergic disease" 105 : 399-408, 2000

      6 R.A.A. Muzzarelli, "The molecular weight of chitosans studied by laser light-scattering" 164 : 433-442, 1987

      7 F. Rousset, "Shifts in interleukin-4 and interferon-gamma production by T cells of patients with elevated serum IgE levels and the modulatory effects of these lymphokines on spontaneous IgE synthesis" 87 : 58-69, 1991

      8 Stein, R. T., "Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years" 354 : 541-545, 1999

      9 P. Ernst, "Relative Scarcity of Asthmaand Atopy among Rural Adolescents Raised on a Farm" 161 : 1563-, 2000

      10 Knorr, D., "Recovery and utilization of chitin and chitosan in food processing waste management" 45 (45): 1991

      11 S. Pastore, "Pathogenetic mechanisms of atopic dermatitis" 481 : 497-, 2000

      12 I. Ikeda, "OH-Radical-induced chain scission of chitosan in the absence and presence of dioxygen" 41 : 431-, 1993

      13 P.C. Molan, "Non - peroxide antibacterial activity in some New Zealand honeys" 27 : 62-, 1988

      14 C.H. Smuith, "New approaches to topical therapy" 25 : 567-, 2000

      15 H. Suto, "NC/Nga Mice: A Mouse Model for Atopic Dermatitis" 120 : 70-75, 1999

      16 H.P. Van der Kleij, "Murine Model for Non-IgE-Mediated Asthma" 28 : 115-, 2004

      17 A. Heinzmann, "Mouse Models for the GeneticDissection of Atopy" 127 : 170-, 2002

      18 K.M. Russell, "Identification of Some Antibacterial Constituentsof New Zealand Manuka Honey" 38 : 10-13, 1990

      19 Weston-RJ, "Identification and quantitative levels of antibacterial components of some New Zealand honeys" 70 : 427-435, 2000

      20 H. Furukawa, "Effects of Bambusae caulis in Liquamen on the development of atopic dermatitis-like skin lesions in hairless mice" 35 : 35-42, 2004

      21 DYM. Leung, "Atopic dermatitis: new insights and opportunistiesfor therapeutic intervention" 105 : 860-876, 2000

      22 S. Leicht., "Atopic dermatitis. How to incorporateadvances in management" 109 : 119-, 2001

      23 M. Boguniewicz, "Anti-viral Activity of Human β-Defensin 3 Against Vaccinia Virus" 117 : 475-, 2006

      24 T. Norikazu, "Analysis of the spontaneous scratching behavior by NC/Nga mice: A possible approach to evaluate antipruritics for subjects with atopic dermatitis" 471 : 223-228, 2003

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      2023 평가예정 재인증평가 신청대상 (재인증)
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      2016-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2015-12-01 평가 등재후보로 하락 (기타) KCI등재후보
      2011-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2007-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2005-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.28 0.28 0.26
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.23 0.23 0.481 0.13
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