Probiotic properties of novel probiotic Levilactobacillus brevis KU15147 isolated from radish kimchi and its antioxidant and immune-enhancing activities

다국어 초록 (Multilingual Abstract)

This study was conducted to evaluate the probioticproperties and antioxidant activities of lactic acidbacteria strains including Levilactobacillus brevisKU15147 isolated from kimchi to determine their potentialas a probiotic. The tolerance of all strains to gastric acidand bile salts was more than 90%. The strains did notproduce a b-glucuronidase and survived following treatmentwith gentamicin, kanamycin, streptomycin, andciprofloxacin. L. brevis KU15147 showed greater adhesionactivity to HT-29 cells (6.38%) and its antioxidant activitieswere higher than those of other tested strains, showingvalues of 38.56%, 22%, and 23.82% in DPPH, ABTS, andb-carotene bleaching assays, respectively. Additionally, therelative expression intensities of induced nitric oxide synthaseand tumor necrosis factor-a of L. brevis KU15147were greater than those of other strains, suggesting that thisstrain can be applied in the health food or pharmaceuticalindustry as a novel probiotic strain.

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