Data on the Characteristics and the Survival of Korean Patients With Colorectal Cancer From the Korea Central Cancer Registry|RISS 상세보기

다국어 초록 (Multilingual Abstract)

Purpose: The incidence rates of colorectal cancer (CRC) in Korea have been increasing during the past decade. Therefore, it is important to understand the characteristics, including survival, of Korean CRC patients. The aim of this study was to use the nationwide cancer registry to evaluate the characteristics of Korean CRC, focusing on the survival, according to tumor location, sex, and specific age groups.
Methods: Using the Korea Central Cancer Registry (KCCR), we analyzed a total of 226,352 CRC cases diagnosed from 1993 to 2010. The five-year relative survivals were compared for the proximal colon, the distal colon, and the rectum. Survival rates were compared between men and women and between patients of young age (less than 40 years old) and patients of advanced age (70 years old or older).
Results: The 5-year survival rates were improved in all subsites between 1993 and 2010. Distal colon cancer showed favorable survival compared to proximal colon or rectal cancer. Females demonstrated worse survival for local or regional cancers,and this difference was significant in for patients in their seventies. Young patients (<40 years old) showed better survival rates for overall and proximal colon cancer comparable to those for older patients (≥40 years old), but advanced age patients (≥70 years old) had worse survivals for all tumor subsites compared to their younger counterparts (<70 years old). These trends were similar in distant CRC.
Conclusion: Korean CRC has certain distinct characteristics of survival according to tumor location, sex, and age. Despite the limitations of available data, this study contributes to a better understanding of survival differences in Korean CRC.

번역하기

참고문헌 (Reference)

1 Chung YF, "Young age is not a poor prognostic marker in colorectal cancer" 85 : 1255-1259, 1998

2 Larsen IK, "Trends in colorectal cancer incidence in Norway 1962-2006: an interpretation of the temporal patterns by anatomic subsite" 126 : 721-732, 2010

3 Singh H, "Time trends in colon cancer incidence and distribution and lower gastrointestinal endoscopy utilization in Manitoba" 103 : 1249-1256, 2008

4 Konyalian VR, "The role of primary tumour resection in patients with stage IV colorectal cancer" 9 : 430-437, 2007

5 Cook AD, "Surgical resection of primary tumors in patients who present with stage IV colorectal cancer: an analysis of surveillance, epidemiology, and end results data, 1988 to 2000" 12 : 637-645, 2005

6 Cheng X, "Subsitespecific incidence rate and stage of disease in colorectal cancer by race, gender, and age group in the United States, 1992-1997" 92 : 2547-2554, 2001

7 Shin A, "Site-specific risk factors for colorectal cancer in a Korean population" 6 : e23196-, 2011

8 Chung SJ, "Prevalence and risk of colorectal adenoma in asymptomatic Koreans aged 40-49 years undergoing screening colonoscopy" 25 : 519-525, 2010

9 Ho C, "Outcomes in elderly patients with advanced colorectal cancer treated with capecitabine: a population- based analysis" 5 : 279-282, 2005

10 Suttie SA, "Outcome of right- and left-sided colonic and rectal cancer following surgical resection" 13 : 884-889, 2011