비인슐린 의존성 당뇨병환자들의 최대하 운동시 나타나는 심맥기능에 관한 연구 = The Study of Cardiovascular Function Duriung Submaximal Exercise in Non-insulin Dependent Diabetes Mellitus Patients

다국어 초록 (Multilingual Abstract)

The purpose of present study was to determine the differences in cardiovascular function between non-diabetic subjects and non-insulin dependent diabetics. Twenty-one male and seven female with non-insulin dependent diabetes mellitus(NIDDM) without any complications(age ranged 40-59 yr). and sixteen male and eleven female without diabetes mellitus(age ranged 40-59 yr) were placed into two groups. Glucose level, percent of body fat, TCH, HDL-C, LDL-C, and triglyceride values were determined prior to maximal exercise stress test using the Bruce protocol.
Results indicate no significant difference in HDL-C, LDL-C and TCH/HDL between groups while non-diabetic individuals(p<0.05). In terms of body fat level, female diabetic subjects had a higher percent of body fat compared with male diabetic subjects(p<0.05).
Systolic and diastolic blood pressures during exercise test in diabetic subjects were significantly higher than those in non-diabetic subjects(p<0.05). In addition, heart rate in non-diabetic subjects showed a significantly faster recovery compared to that in diabetic subjects(p<0.05).
In the comparison by gender, blood pressure in female subjects before, after, and during the exercise stress test was significantly higher that that in male subjects(p<0.05) while no significant difference in heart rate was found between male and female.
Moreover, in the comparison by age, the subjects in their 50s revealed higher blood pressure before, after, and during the exercise stress test compared with the subjects in their 40s(p<0.05). In the case of heart rate response slightly slower increase in heart rate was observed in the subjects in their 50s compared to that in the subjects in their 40s.
In comparison between two diabetic groups divided by TCH and LDL-C values, the group with higher THC and LDL-C values had significantly higher systolic and diastolic blood pressures before, after and during the exercise test(p<0.05). However, in the comparison between two diabetic groups divided by HDL-C values and TCH/HDL-C, there was no significant differences in blood pressure between the groups. Additionally, slightly faster increase in heart rate during exercise stress test was appeared in the group with higher serum lipid concentration level.
In comparison between two groups divided by percent of body fat, there was no significant difference in blood pressure between the groups before, after and during exercise stress test. On the other hand, the group with beyond the normal range of percent body fat revealed higher absolute value of systolic blood pressure during the exercise stress test. Heart rate in the group with beyond the normal range of percent body fat showed a significantly slower recovery after exercise stress test compared to that in group with normal range of percent body fat(p<0.05).