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      특발성 파킨슨병 환자에 대한 한의치료의 효과 : 후향적 연구 = Effects of Korean Medicine on Patients with Idiopathic Parkinson’s Disease: A Retrospective Study

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      https://www.riss.kr/link?id=A102417426

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      다국어 초록 (Multilingual Abstract)

      Objectives: The purpose of this study was to investigate the effects of Korean medicine on patients with idiopathic Parkinson’s disease.Methods: The charts of 47 patients diagnosed with idiopathic Parkinson’s disease in the Department of...

      Objectives: The purpose of this study was to investigate the effects of Korean medicine on patients with idiopathic Parkinson’s disease.Methods: The charts of 47 patients diagnosed with idiopathic Parkinson’s disease in the Department of Internal Korean medicine, Stroke and Neurological Disorders Center, Kyung Hee University Hospital, Gangdong between August 2012 and July 2016 were reviewed. The Unified Parkinson’s disease rating scale (UPDRS) was administered before and after treatment with Korean medicine.Results: Thee average UPDRS Ⅱ+Ⅲ, UPDRS Ⅱ, and UPDRS Ⅲ of the 47 patients decreased significantly from 22.26±15.15, 10.19±7.53, and 12.06±8.35, respectively, pretreatment to 16.96±13.63, 7.47±6.44, and 9.49±7.73, respectively, post-treatment. The average postural instability and gait difficulty (PIGD), tremor, and bradykinesia also significantly improved post-treatment.Conclusions: These results provide evidence that Korean medicine can improve the activities of daily living and motor function of patients with idiopathic Parkinson’s disease. In particular, Korean medicine may be effective for the treatment of PIGD, tremor, and bradykinesia.

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      참고문헌 (Reference)

      1 박상민, "파킨슨병의 한의학적 고찰 -병인병리와 침구요법을 중심으로-" 대한침구의학회 21 (21): 202-210, 2004

      2 이영은, "파킨슨병 환자의 자세 불안정과 보행장애에 대한 한양방 복합치료 3예" 경락경혈학회 31 (31): 40-47, 2014

      3 우찬, "사람 신경모세포종 SH-SY5Y 세포주의 파킨슨 모델에 대한 小續命湯의 보호효과" 대한한방내과학회 35 (35): 298-308, 2014

      4 최재송, "熱多寒少湯加減方으로 호전된 파킨슨병 환자 1례" 사상체질의학회 24 (24): 104-113, 2012

      5 Kim SR, "Use of complementary and alternative medicine by Korean patients with Parkinson's disease" 111 (111): 156-160, 2009

      6 Bae N, "The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease" 134 (134): 313-322, 2011

      7 Hirsch MA, "The effects of balance training and high-intensity resistance training on persons with idiopathic Parkinson's disease" 84 (84): 1109-1117, 2003

      8 Shulman LM, "The clinically important difference on the unified Parkinson’s disease rating scale" 67 (67): 64-70, 2010

      9 Shulman LM, "The clinically important difference on the unified Parkinson’s disease rating scale" 67 (67): 64-70, 2010

      10 Langston JW, "The Parkinson's complex: parkinsonism is just the tip of the iceberg" 59 (59): 591-596, 2006

      1 박상민, "파킨슨병의 한의학적 고찰 -병인병리와 침구요법을 중심으로-" 대한침구의학회 21 (21): 202-210, 2004

      2 이영은, "파킨슨병 환자의 자세 불안정과 보행장애에 대한 한양방 복합치료 3예" 경락경혈학회 31 (31): 40-47, 2014

      3 우찬, "사람 신경모세포종 SH-SY5Y 세포주의 파킨슨 모델에 대한 小續命湯의 보호효과" 대한한방내과학회 35 (35): 298-308, 2014

      4 최재송, "熱多寒少湯加減方으로 호전된 파킨슨병 환자 1례" 사상체질의학회 24 (24): 104-113, 2012

      5 Kim SR, "Use of complementary and alternative medicine by Korean patients with Parkinson's disease" 111 (111): 156-160, 2009

      6 Bae N, "The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease" 134 (134): 313-322, 2011

      7 Hirsch MA, "The effects of balance training and high-intensity resistance training on persons with idiopathic Parkinson's disease" 84 (84): 1109-1117, 2003

      8 Shulman LM, "The clinically important difference on the unified Parkinson’s disease rating scale" 67 (67): 64-70, 2010

      9 Shulman LM, "The clinically important difference on the unified Parkinson’s disease rating scale" 67 (67): 64-70, 2010

      10 Langston JW, "The Parkinson's complex: parkinsonism is just the tip of the iceberg" 59 (59): 591-596, 2006

      11 Li F, "Tai Chi and Postural Stability in Patients with Parkinson’s Disease" 366 (366): 511-519, 2012

      12 Ramaker C, "Systematic evaluation of rating scales for impairment and disability in Parkinson's disease" 17 (17): 867-876, 2002

      13 Herd CP, "Speech and language therapy versus placebo or no intervention for speech problems in Parkinson's disease" 15 (15): CD002812-, 2012

      14 Shulman LM, "Randomized clinical trial of 3 types of physical exercise for patients with Parkinson disease" 70 (70): 183-190, 2013

      15 Connolly BS, "Pharmacological treatment of Parkinson disease: a review" 311 (311): 1670-1683, 2014

      16 Doo AR, "Neuroprotective effects of an herbal medicine, Yi-Gan San on MPP+/MPTP -induced cytotoxicity in vitro and in vivo" 131 (131): 433-442, 2010

      17 Schrag A, "Minimal clinically important change on the unified Parkinson’s disease rating scale" 21 (21): 1200-1207, 2006

      18 김인자, "MPTP로 유도된 Parkinson’s disease 동물 모델을 이용한 蘇合香元의 신경보호 효과 및 그 작용 기전 연구" 대한한방신경정신과학회 23 (23): 129-143, 2012

      19 고가연, "MPTP로 유도된 Parkinson's disease 동물 모델에서 열다한소탕 가감방 (MYH)의 신경 세포 보호 효과" 사상체질의학회 27 (27): 270-287, 2015

      20 고가연, "MPTP(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)로 유도된 Parkinson's Disease 동물 모델을 이용한 향사양위탕의 신경 세포 보호 효과" 사상체질의학회 26 (26): 165-179, 2014

      21 Kwakkel G, "Impact of physical therapy for Parkinson's disease: a critical review of the literature" 13 : 478-487, 2007

      22 Kim TH, "Herbal medicines for Parkinson's disease: a systematic review of randomized controlled trials" 7 (7): e35695-, 2012

      23 Zhang G, "Effectiveness of traditional Chinese medicine as an adjunct therapy for Parkinson's disease: a systematic review and meta-analysis" 10 (10): e0118498-, 2015

      24 Ishikawa T, "Effectiveness of the Kampo kami-shoyo-san(TJ-24) for tremor of antipsychotic-induced parkinsonism" 54 (54): 579-582, 2000

      25 Cho SY, "Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease" 18 (18): 948-952, 2012

      26 Wang F, "Effect and Potential Mechanism of Electroacupuncture Add-On Treatment in Patients with Parkinson's Disease" 2015 : 692795-, 2015

      27 Toosizadeh N, "Does integrative medicine enhance balance in aging adults? Proof of concept for the benefit of electroacupuncture therapy in Parkinson's disease" 61 (61): 3-14, 2015

      28 Gelb DJ, "Diagnostic criteria for Parkinson disease" 56 (56): 33-39, 1999

      29 Hauser RA, "Determination of minimal clinically important change in early and advanced Parkinson's disease" 26 (26): 813-818, 2011

      30 Leon Shargel, "Comprehensive pharmacy review" Lippincott-Raven Publishers 998-, 2007

      31 Li H, "Anti-apoptotic effect of modified Chunsimyeoldatang, a traditional Korean herbal formula, on MPTP-induced neuronal cell death in a Parkinson's disease mouse model" 176 : 336-344, 2015

      32 Robert AH, "A translation of Parkinson’s disease: Questions and answers" Panmun Book Co 99-, 2005

      33 Lee JH, "A clinical report on the mild case of Parkinson's disease improved with Soyangin-Gihwangbeakho-tang" 14 (14): 153-159, 2002

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2022 평가예정 재인증평가 신청대상 (재인증)
      2019-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2016-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2015-12-01 평가 등재후보로 하락 (기타) KCI등재후보
      2011-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2009-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-02-09 학술지명변경 외국어명 : THE KOREAN SOCIETY FOR ORIENTAL INTERNAL MEDICINE -> The Journal of Korean Oriental Internal Medicine KCI등재
      2006-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2005-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.67 0.67 0.61
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.56 0.5 0.653 0.03
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