<P>Molecular and virulence characteristics of CTX-M-producing and non-extended-spectrum-β-lactamase (non-ESBL)-producing <I>Klebsiella pneumoniae</I> isolates were compared. Lack of shared characteristics between the two group...
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https://www.riss.kr/link?id=A107644059
2014
-
SCI,SCIE,SCOPUS
학술저널
2463-2467(5쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P>Molecular and virulence characteristics of CTX-M-producing and non-extended-spectrum-β-lactamase (non-ESBL)-producing <I>Klebsiella pneumoniae</I> isolates were compared. Lack of shared characteristics between the two group...
<P>Molecular and virulence characteristics of CTX-M-producing and non-extended-spectrum-β-lactamase (non-ESBL)-producing <I>Klebsiella pneumoniae</I> isolates were compared. Lack of shared characteristics between the two groups suggested that most CTX-M-producing <I>K. pneumoniae</I> isolates in South Korea did not occur by transfer of <I>bla</I><SUB>CTX-M</SUB> into susceptible strains. Conjugation assays confirmed that the plasmid with the <I>bla</I><SUB>CTX-M-15</SUB> gene confers virulence as well as antimicrobial resistance, suggesting that a CTX-M-15-producing clone such as ST11 may have a selective advantage even without antibiotic pressure.</P>