一部醫科大學 및 齒科大學生들의 B型肝炎 感染率에 關한 硏究

국문 초록 (Abstract)

全南大學校 醫科大學 및 齒科大學生 總 1,158 名 中 肝炎豫防接種을 받은적이 없고 本 然究에 參與하기를 원하는 403名을 對象으로 HBsAg, Anti HBs를 RPHA (Reverse Passive Hemagglutination-Method) 法으로 檢査하여 HBsAg陽性率과 HBV感染率을 調査하고 肝機能檢査(sGOT)를 實施하였으며 設問紙를 通한 危險要素와의 關聯性을 分析하여 다음과 같은 結論을 얻었다.
1. 醫科大學 및 齒科大學 對象者 403名중 HBsAg 陽性인 者는 25名으로 6.2%, Anti -HBs陽性인 者는 118名으로 29.3%, HBV感染을 받은者는 143名으로 35.5%로 나타났다.
2. 大學別로는 HBsAg, Anti-HBs陽性率 및 HBV感染率이 醫科大學은 各各 7.6%, 30.9 %, 38.6 %였으며 齒科大學은 4.2%, 26.9%, 31.1%로 모두 醫大가 齒大보다 높게 나타났으나 有意한 差異는 없었다
3. 年令別로는 醫科大學 및 齒科大學이 모두 HBsAg은 年令增加에 따른 一貫性있는 變化를 보이지 않았으나 Anti-HBs 陽性率과 HBV感染率은 나이가 增加함에 따라 增加하는 傾向을 보였으며 全體的으로 HBsAg은 21歲에서 10.0%로 가장 높게 나타났으며 Anti - HBs 陽性率과 HBV 感染率은 各各 25歲 以上에서 40.7%, 47.5%로 가장 높게 나타나 年令增加에 따른 增加 傾向을 보였다.
4. 性別로는 齒科大學生들의 HBsAg 陽性率은 男女가 같게 나타났으나 Anti HBs陽性率과 HBV感染率은 醫科大學 및 齒科大學이 모두 女子보다 男子에서 높게 나타났으며 全體的으로는 HBV感染率이 男子가 39.0 %, 女子가 27.8%로 女子보다 男子에서 有意하게 높게 나타났다(P<0.05).
5. 學年別 分布를 보면 全體的으로 HBsAg은 學年이 增加함에 따라 減少하는 傾向을 보였으나 Anti - HBs陽性率과 HBV感染率은 대체로 1, 2學年 보다 3, 4學年에서 높은 傾向을 보였다.
6. 危險要因과 HBV 感染率과의 關聯性을 보면 手術力과 鍼術力이 Odds ratio 2.3 및 3.4 로 나타나 HBV感染의 危險要因으로 作用할 可能性이 有意하게 높게 나타났다(P<0.01).

다국어 초록 (Multilingual Abstract)

To determine the hepatitis B viral infection rate of medical and dental students 414 students of medical and dental schools of chonnam National University who had not been vaccinated and volunteered to participate in this study were tested for HBsAg and Anti HBs with RPHA(Reverse Passive Hemagglutination) and s-GOT with Reitman-Frankel method. Some informations were collected to investigate related factors to HBV infection.
The results obtained are as follows;
1. As a whole, the postive rate in medical and dental students of HBsAg was 6.2%, that of Anti-HBs was 29.8%, and HBV infection rate was 35.5%
2. By school, the positive rates of HBsAg, Anti-HBs and HBV infection rate were 7.6%,30.9% and 38.6% in Medical students, and 4.2%,26.9% and 31.1% in Dental students.
3. Anti-HBs positive rate and HBV infection rate showed an increasing trend as age increased in both group. HBsAg positive rate was the highest in 21 years of age while Anti HBs positive rate (40.7%) and HBV infection rate (47.5%) were highest in 25 years and older age group.
4. Overall positive rates of HBsAg, Anti HBs and HBV infection rates were generally higher in male as 7.2%, 31.8% and 39.0%, while those rates of female were 4.0%, 23.8% and 27.8%. But only HBV infection rate was significantly different by sex (P<0.05).
5. Generally, Anti-HBs positive rate and HBV infection rate were higher in 3rd and 4th grade than 1st and 2nd school grade students.
6. Odds ratios of HBV infection to related factors were high and significant in students who have previous operation history and accupuncture history (p<0.01).

목차 (Table of Contents)

• 목차
• 國文抄錄 = 1
• I. 緖論 = 3
• II. 調査對象 및 方法 = 4
• III. 成績 = 5
• IV. 考察 = 15
• V. 結論 = 20
• 參考文獻 = 22
• 英文抄錄 = 26