첨가성분에 따른 부가중합 실리콘 인상재의 세포독성에 관한 연구 = Cytotoxicity of Polyvinyl Siloxane Impression Materials

다국어 초록 (Multilingual Abstract)

The purpose of this study was to evaluate the biocompatibility of polyvinyl siloxane impression materials and it's components using cell culture techniques. In the cytotoxicity test, using the culture of L929 mouse fibroblast, the degree of gross cytotoxic effects on the cells by changes in the cell morphology was scored for each materials. And the changes in the cell membrane permeability was tested using the agar overlay test. The results were as follows:
1.The effect of Examix impression material had on cell viability by evaluating survival rates was more severe than any other materials and newly added surfactants.
2.NP-4, nonylphenoxy polyethylene ethanol homologs, showed some cytotoxicity than PC-550 and BYK066.
3.In the test of the changes in cell membrane permeability using the agar overlay method, any cytotoxicity was recorded in silicone base groups.
3.In agar overlay test, Examix and NP-4 showed most response index and lysis index.
4.The application of surfactant such as PC-550, NP-4, and BYK066 might be considered relatively biocompatible.

목차 (Table of Contents)

• 서론
• 재료 및 방법
• 1.연구재료
• 2.인상재
• 3.세포 및 배양액
• 연구방법
• 1.세포증식 및 세포생존률 검사
• 2.한천증층검사
• 결과
• 1.세포 증식 및 세포생존율 검사
• 2.한천증층검사
• 고찰
• 결론