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      The effects of a proprietary Manuka honey and essential oil hydrogel on the healing of acute full‐thickness wounds in dogs

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      https://www.riss.kr/link?id=O108050601

      • 저자
      • 발행기관
      • 학술지명
      • 권호사항
      • 발행연도

        2021년

      • 작성언어

        eng

      • Print ISSN

        0161-3499

      • Online ISSN

        1532-950X

      • 등재정보

        SCI;SCIE;SCOPUS

      • 자료형태

        학술저널

      • 원정보자원

        Veterinary surgery

      • 수록면

        1634-1643   [※수록면이 p5 이하이면, Review, Columns, Editor's Note, Abstract 등일 경우가 있습니다.]

      • 소장기관
      • 구독기관
        • 전북대학교 중앙도서관  
        • 성균관대학교 중앙학술정보관  
        • 부산대학교 중앙도서관  
        • 전남대학교 중앙도서관  
        • 제주대학교 중앙도서관  
        • 중앙대학교 서울캠퍼스 중앙도서관  
        • 인천대학교 학산도서관  
        • 숙명여자대학교 중앙도서관  
        • 서강대학교 로욜라중앙도서관  
        • 충남대학교 중앙도서관  
        • 한양대학교 백남학술정보관  
        • 이화여자대학교 중앙도서관  
        • 고려대학교 도서관  
      • ⓒ COPYRIGHT THE BRITISH LIBRARY BOARD: ALL RIGHT RESERVED
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      다국어 초록 (Multilingual Abstract)

      To evaluate the effect of a proprietary Manuka honey essential oil hydrogel on the healing of acute, full‐thickness wounds in dogs. Prospective, controlled, randomized, experimental study. Purpose‐bred, adult, female beagles (n = 10). Two 2�...

      To evaluate the effect of a proprietary Manuka honey essential oil hydrogel on the healing of acute, full‐thickness wounds in dogs.
      Prospective, controlled, randomized, experimental study.
      Purpose‐bred, adult, female beagles (n = 10).
      Two 2 × 2 cm surgical wounds were created bilaterally on the trunk of each dog; each side was randomized to receive HoneyCure® (HOC) or standard‐of‐care (CON) dressings. Cranial wounds were for histopathological analysis and the caudal wounds for culture and planimetry. Total and open wound areas were measured with digital image planimetry at 15 time points. From these data, percent contraction and percent epithelialization were calculated. Tissue biopsies were obtained at 7 time points and histologic features scored. Cultures were obtained at 2 time points.
      Epithelialization was 11.7, 10.4, and 10.1 percentage points higher in HOC wounds compared to CON wounds at days 16, 18, and 21 respectively. Wound contraction and histological scores did not differ between groups. Cultures were positive in 7/40 (17.5%) wounds, with Staphylococcus pseudintermedius and Staphylococcus epidermidis isolated evenly. There was no difference of infection rate between the two groups; all infections were superficial and did not require treatment.
      This study did not provide evidence to support the application of HoneyCure® in small, acute wounds in healthy dogs. However, application may be beneficial in the early proliferative stage of wound healing and in wounds that would benefit from early, robust epithelialization.

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