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1 Wang Y, "The predictive role of phosphatase and tensin homolog (PTEN) loss, phosphoinositol-3 (PI3) kinase (PIK3CA)mutation, and PI3K pathway activation in sensitivity to trastuzumab in HER2-positive breast cancer: a meta-analysis" 29 : 633-642, 2013
2 Ibrahim EM, "The predictive and prognostic role of phosphatase phosphoinositol-3(PI3)kinase(PIK3CA)mutation in HER2-positive breast cancer receiving HER2-targeted therapy : a meta-analysis" 152 : 463-476, 2015
3 Engels CC, "The clinical value of HER-2 overexpression and PIK3CA mutations in the older breast cancer population : a FOCUS study analysis" 156 : 361-370, 2016
4 Bachman KE, "The PIK3CA gene is mutated with high frequency in human breast cancers" 3 : 772-775, 2004
5 Wolff AC, "Recommendations for human epidermal growth factor receptor 2 testing in breast cancer : American Society of Clinical Oncology/College of American Pathologists clinical practice guideline update" 31 : 3997-4013, 2013
6 Tolaney S, "Phase I/II study of pilaralisib(SAR245408)in combination with trastuzumab or trastuzumab plus paclitaxel in trastuzumab-refractory HER2-positive metastatic breast cancer" 149 : 151-161, 2015
7 Goel S, "PIK3CA mutations in HER2-positive breast cancer : an ongoing conundrum" 27 : 1368-1372, 2016
8 Loibl S, "PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer : pooled analysis of 967 patients from five prospective trials investigating lapatinib and trastuzumab" 27 : 1519-1525, 2016
9 Majewski IJ, "PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2-targeted therapies in breast cancer" 33 : 1334-1339, 2015
10 Kalinsky K, "PIK3CA mutation associates with improved outcome in breast cancer" 15 : 5049-5059, 2009
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