본 연구는 관상동맥질환 환자에서 안정시 심박변동 및 최대운동 후 심박수 회복을 통해 베타 차단제가 자율신경계에 미치는 영향을 알아 보고자 시행되었다. 연구의 대상자는 정상군 16명, ...
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https://www.riss.kr/link?id=A75526290
2006
-
600
KCI등재
학술저널
23-32(10쪽)
6
0
상세조회0
다운로드국문 초록 (Abstract)
본 연구는 관상동맥질환 환자에서 안정시 심박변동 및 최대운동 후 심박수 회복을 통해 베타 차단제가 자율신경계에 미치는 영향을 알아 보고자 시행되었다. 연구의 대상자는 정상군 16명, ...
본 연구는 관상동맥질환 환자에서 안정시 심박변동 및 최대운동 후 심박수 회복을 통해 베타 차단제가 자율신경계에 미치는 영향을 알아 보고자 시행되었다. 연구의 대상자는 정상군 16명, 관상동맥질환 환자 중 베타차단제 비투여군 13명, 관상동맥질환 환자 중 베타차단제 투여군 9명의 세군으로 구분하여 안정시 심박변동 및 최대강도의 트레드밀 운동 후 5분간의 심박수 회복을 평가하였다. 심박변동은 시간영역 분석방법을 통한 RR간격의 표준편차(the standard deviation of the NN interval; SDNN), RMSSD(the root mean square successive differences)와 주파수영역 분석방법을 통한 저주파영역 전력(low frequency power; LF), 고주파영역 전력(high frequency power; HF), 저주파영역/고주파영역 비(LF/HF ratio)를 구하여 평가하였다. 심박수 회복은 최대심박수와 회복기 심박수의 차이로 최대운동 후 5분 동안 1분 간격으로 심박수를 측정하여 구하였다. 심박수 회복의 평가에서 개개인의 최대심박수 차이에 따른 영향을 극복하기위해 여유심박수 백분율[(회복기 심박수-안정시 심박수)/(측정된 최대심박수-안정시 심박수)×100]을 구하여 이용하였다. 결과는 다음과 같다. SDNN과 저주파영역 전력은 관상동맥질환 환자군에서 정상군보다 유의하게 낮았으나 베타 차단제 투여군과 비투여군 사이에는 심박변동의 모든 지표에서 유의한 차이가 없었다. 반면 최대강도운동 후 회복기에 매분마다의 심박수는 베타차단제 투여군이 정상군에 비하여 유의하게 낮았고, 심박수 회복은 정상군이 베타차단제 비투여군과 투여군에 비하여 유의하게 높았다. 회복기 여유심박수 백분율은 베타차단제 비투여군이 정상군에 비해 최대운동 후 회복기 1분, 2분, 3분대에서 유의하게 낮았으며, 정상군과 베타차단제 투여군 사이에는 유의한 차이가 없었다. 이상의 결과로 관상동맥질환 환자는 정상인에 비하여 교감신경 활동도는 증가되어 있고, 부교감신경 활동도는 감소되어 있는 것을 알 수 있었으며, 베타 차단제는 자율신경계를 정상화시켜 관상동맥질환 환자의 심박수 회복율을 증가시키는 것으로 생각한다.
다국어 초록 (Multilingual Abstract)
The purpose of this study was to evaluate the effect of beta blocker on autonomic nervous activity with using heart rate recovery(HRR) after maximum exercise and heart rate variability(HRV) at rest for coronary artery disease(CAD) patients. The 38 sub...
The purpose of this study was to evaluate the effect of beta blocker on autonomic nervous activity with using heart rate recovery(HRR) after maximum exercise and heart rate variability(HRV) at rest for coronary artery disease(CAD) patients. The 38 subjects were divided into three groups. The control group consisted of 16 normal subjects. The non beta blocker group consisted of 13 CAD patients who didn`t take beta blocker. The beta blocker group consisted of 9 CAD patients who took beta blocker. Time domain and frequency domain of HRV were measured in three groups at rest. The time domain consisted of the standard deviation of the NN interval(SDNN) and the root mean square successive differences(RMSSD). The frequency domain consisted of low frequency power(LF), high frequency power(HF), and LF/HF ratio. Heart rate, HRR(maximum heart rate-heart rate at recovery stage), the percent of heart rate reserve{(heart rate at recovery stage-resting heart rate)/(measured maximum heart rate-resting heart rate)×100} were evaluated during five minutes after maximum exercise. The criteria for maximum exercise were a respiratory exchange ratio of 1.1 or 90% of the age determined maximum heart rate. The SDNN and LF were significantly lower in both beta and non beta blocker groups than in control group. However, there was no significant difference between beta blocker group and non beta blocker group. Heart rate during five minutes after maximum exercise was significantly lower in beta blocker group than in control. HRR from the maximal heart rate during five minutes after exercise was significantly higher in control group than in beta blocker and non beta blocker groups. The percent of heart rate reserve in control group was significantly lower than non beta blocker group at 1, 2 and 3 minutes after exercise. There was no significant difference between beta blocker group and control group for the percent of heart rate reserve. This study demonstrated reduced control of the autonomic nervous activity and delayed heart rate recovery in CAD patients. HRR in CAD patients was normalized by beta blocker. Beta blocker improve balance of autonomic nervous activity in CAD patients.
참고문헌 (Reference)
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1 "심박변동의 Power Spectrum 분석에 의한 정상 성인의 자율신경기능 평가" 928-935, 1997
2 "the impact of coronary heart disease on patients' daily activities" 1642-1647, 1985
3 "standards of measurement Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology" 1043-1065, 1996
4 "Vagally mediated heart rate recovery after exercise is accelerated in athletes but blunted in patients with chronic heart failure" 1529-1535, 1994
5 "The role of beta adrenergic blocking agents in preventing sudden cardiac death" 1-, 1992
6 "Spinal sympathetic reflexes initiated by coronary receptors" 685-705, 1971
7 "Prognostic role of heart rate variability in patients with a recent acute myocardial infarction" 1323-1328, 1998
8 "Modulation of cardiac autonomic activity during and immediately after exercise" 1989
9 "Insights from the study of heart rate variability" 249-261, 1999
10 "Heart rate variability in patients with acute myocardial infarction undergoing primary coronary angioplasty" 815-820, 2000
11 "Heart rate variability during the acute phase of myocardial infarction" sig (sig): 2073-2079, 1992
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근력훈련이 다운증후군 청년의 발목 관절에 작용하는 회전력에 미치는 영향
구매결정요인에 따른 스포츠의류 시장세분화 및 세분시장 특성 분석
트레드밀 운동이 스트렙토조토신으로 당뇨 유발 후 좌골신경 손상 쥐의 신경재생, 척수운동신경세포, GAP-43와 GLUT-4 단백질 발현에 미치는 영향
학술지 이력
연월일 | 이력구분 | 이력상세 | 등재구분 |
---|---|---|---|
2027 | 평가예정 | 재인증평가 신청대상 (재인증) | |
2021-01-01 | 평가 | 등재학술지 유지 (재인증) | |
2018-06-08 | 학회명변경 | 한글명 : 국민체육진흥공단 부설 한국스포츠개발원 -> 국민체육진흥공단 한국스포츠정책과학원 | |
2018-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2017-04-11 | 학회명변경 | 영문명 : 미등록 -> Korea Institute of Sport Science | |
2015-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2014-03-24 | 학회명변경 | 한글명 : 국민체육진흥공단 체육과학연구원 -> 국민체육진흥공단 부설 한국스포츠개발원 | |
2013-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2010-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2008-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2006-01-01 | 평가 | 등재학술지 유지 (등재유지) | |
2005-07-01 | 학술지등록 | 한글명 : 체육과학연구외국어명 : Korean Journal of Sport Science | |
2003-01-01 | 평가 | 등재학술지 선정 (등재후보2차) | |
2002-01-01 | 평가 | 등재후보 1차 PASS (등재후보1차) | |
2001-07-01 | 평가 | 등재후보학술지 선정 (신규평가) |
학술지 인용정보
기준연도 | WOS-KCI 통합IF(2년) | KCIF(2년) | KCIF(3년) |
---|---|---|---|
2016 | 0.78 | 0.78 | 0.84 |
KCIF(4년) | KCIF(5년) | 중심성지수(3년) | 즉시성지수 |
0.8 | 0.84 | 0.781 | 0.21 |