갑상선 기능 저하를 일으킨 흰쥐의 고온, 한냉 속에서 본 산소 소모량 및 체온의 변동 = Changes in Oxygen Uptake and Body Temperature of Propylthiouracil Treated Rats in Various Ambient Temperatures

다국어 초록 (Multilingual Abstract)

Charges in oxygen uptake and body temperature of rats whose thyroid glands were made hypofunctional by means of propylthiouracil administration in response to the change in environmental temperature were observed. Propylthiouracil was fed with diet for 3 weeks. Male rats (average body weight, 200gm) were put into glass cylinder of which was surrounded with air or water of varying temperature. The rats in the glass cylinder were kept relatively in a resting state. The temperature in the glass cylinder was maintained at 15℃, 4℃ and 39℃ for 50-80 minutes. In this experimental period oxygen uptake and body temperature were measured at 10 minutes interval.
The following results wert obtained.
1. Cxygen uptake at 15℃ of environmental temperature in normal control rats ranged between 31.2 and 39.9㎖/kg/min, and in experimental rats oxygen uptake ranged between 20.9 and 23.8㎖/kg/min.
Oxygen uptake at 39℃ of environmental temperature in normal control rats ranged between 18.6 and 33.0㎖l/kg/min, and in experimental rats it ranged between 13.7 and 20.6㎖/kg/min. Thus, at highertemperature oxygen uptake decreased both in control and experimental rats and the magnitude of decrease was a greater in experimental rats than in control rats. Oxygen uptake at 4℃ of environmental temperature in control rats ranged between 25.9 and 65.0㎖/kg/min, and in experimental rats it ranged between 11.7 and 39.9㎖/kg/min. Oxygen uptake at 4℃ in experimental rats was smaller than in control rats. During the experimental Belied of 50 to 80 minutes, oxygen uptake in both control and experimental rats decreased progressively.
2. Fectal temperature at 15℃ environmental temperature in control rats ranged between 34.6 and 36.1℃ and in experimental rats it ranged between 31.0 and 31.5℃. When environmental temperature was raised to 39℃, rectal temperature of control rats ranged between 37.5 and 40.9℃ and in experimental rats it ranged between 36.2 and 40.3℃. The rectal temperature in hot environment showed an increasing trend during the experimental period. At 4℃ rectal temperature of control fats ranged between 26.0 and 36.1℃ and experimental temperature was lower than in control rats and it ranged between 17.9 and 33.6℃.
3. Skin temperature on midanterior thoracic cafe and midthigh at 15℃ in control rats ranged between 30.8 and 31.7℃ and in experimental rats it ranged-between 26.7 and 28.5℃.
4. Thermal circulating index at 15℃ in control rats ranged between 3.4 and 4.6 and in experimental rats it ranged between 2.7 and 4.5.
Heat conductance of skin at 15℃ in control rats ranged between 0.037 and 0.062 kcal/kg/min/degreeC, and in experimental rats it ranged between 0.023 and 0.038 kcal/kg/min/degree C.

목차 (Table of Contents)

• Ⅰ. 서론
• Ⅱ. 실험방법
• Ⅲ. 실험성적
• Ⅳ. 고찰
• Ⅴ. 결론
• 참고문헌