스라이드임신진단법과 한국산 개구리 임신진단법의 비교관찰 = Comparative Study of Slide Pregnancy Test and Frog Test

다국어 초록 (Multilingual Abstract)

Recent advances in immunology have opened a new approach to a rapid, inexpensive, and accurate test for detecting pregnancy. I have had the opportunity of evaluating a new rapid slide pregnancy test, marketed as Gravindex slide test for preguancy, supplied by Ortho Pharmaceutical Corporation, which is based on the principle of inhibition of agglutination of HCG-coated latex particles by anti-HCG serum when HCG is present the test urine. The purpose of my study was to determine whether such in vitro pregnancy was reliable enough to replace the biological test. A comparative study simultaneously employing the Korean frog test was conducted and the results were as follows; 1) 14 cases of normal pregnancy, 6 cases of non-pregnant women, 1 case of male, 2 cases of threatened abortion, 2 cases of choriocarcinoma, and 1 case of hydatidiform mole, totalling 26 cases, were studied with slide test and frog test. 2) General diagnostic accuracy was 100% with slide test, and 88% with frog test. 3) In pregnant patient diagnostic accuracy was found to be 100% with slide test, and 93% with frog test. 4) In the absence of pregnancy both tests were negative in 100% (No false positive test). 5) Slide test was positive in 100% of abnormal pregnancy, but frog tests were negative in one case of threatened abortion and one case of choriocarcinoma. 6) Accuracy of slide test had no relation to the time of collection and specific gravity of the urine specimen. 7) The slide immunological pregnancy test was fonnd to be a rapid, inexpensive, accurate, and easily performed office procednre, and enough to replace the bilogical test in the clinic and office procedure.