<P>A mouse pulmonary hypersensitivity experimental model that mimics human asthma was developed, and electroacupuncture (EA) treatment was shown to reduce allergic inflammatory processes. In addition, we also assessed whether the beneficial effe...
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https://www.riss.kr/link?id=A107760489
2012
-
학술저널
647308
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P>A mouse pulmonary hypersensitivity experimental model that mimics human asthma was developed, and electroacupuncture (EA) treatment was shown to reduce allergic inflammatory processes. In addition, we also assessed whether the beneficial effe...
<P>A mouse pulmonary hypersensitivity experimental model that mimics human asthma was developed, and electroacupuncture (EA) treatment was shown to reduce allergic inflammatory processes. In addition, we also assessed whether the beneficial effects of EA on allergic asthma could be correlated with CD4<SUP>+</SUP>CD25<SUP>+</SUP>Foxp3<SUP>+</SUP> regulatory T cells (Treg). Cellular profiles and histopathologic analysis demonstrated that peribronchial and perivascular inflammatory cell infiltrates were significantly decreased in the EA-treated groups when compared to the OVA and anti-CD25 Ab-injected (Treg depletion) groups. Furthermore, total BAL cells were reduced in the EA groups when compared to other groups. Interestingly, the population of CD4<SUP>+</SUP>CD25<SUP>+</SUP>Foxp3<SUP>+</SUP>Tregs in pneumonocytes increased in EA-treated group when compared to OVA and Treg depletion groups. These results imply that EA stimulation at ST 36 may affect CD4<SUP>+</SUP>CD25<SUP>+</SUP>Foxp3<SUP>+</SUP> Treg in an OVA-induced experimental model and may enhance Treg function by suppressing other T cells and limiting the immune response.</P>
Prevalence of Metabolic Syndrome according to Sasang Constitutional Medicine in Korean Subjects