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      KCI등재 SCOPUS

      A Convenient HPLC/ELSD Method for the Quantitative Analysis of Betaine in Lycium chinense

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      https://www.riss.kr/link?id=A103821559

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      다국어 초록 (Multilingual Abstract)

      In order to facilitate the quality control of betaine from the fruits of Lycium chinense, we have developed a rapid and simple method for quantitative determination. Determination was achieved on a Discovery C18 column with an isocratic solvent system...

      In order to facilitate the quality control of betaine from the fruits of Lycium chinense, we have developed a rapid and simple method for quantitative determination. Determination was achieved on a Discovery C18 column with an isocratic solvent system of 0.32% perfluoropentanoic acid aqueous-acetonitrile at a flow-rate of 0.5 mL/min and detected an ELSD. The method was reproducible with intra- and inter-day variations of less than 6% (R.S.D). The recoveries were in the range of 90.01~100.05%. The method turned out to be fast and simple, furthermore, to have a good selectivity and sensitivity for the quantity determination of betaine in the fruits of L.chinense.

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      참고문헌 (Reference)

      1 Noguchi, M., "Uber die Bestandteile der chinesischen Droge Ti-ku-'pi.I. Isolierung und Konstitution von Lyciumamid, einem neuen Dipeptid" 32 : 3584-3587, 1984

      2 Gahl, W.A., "The effect of oral betaine on vertebral body bone density in pyridoxine-nonresponsive homocystinuria" 11 : 291-298, 1988

      3 Murakami, T., "The Recovering Effect of Betaine on Carbon Tetrachloride-Induced Liver Injury" 44 : 249-255, 1998

      4 Funayama, S., "Structure of kukoamine A, a hypotensive principle of Lycium chinense root barks1" 21 : 1355-1356, 1980

      5 Kikuchi, N., "Separation and determination of betaine in an oriental medicine by liquid chromatography" 283 : 338-343, 1993

      6 Sannai, A., "Neutral Volatile Components of "Kukoshi" (Lycium chinense M.)" 47 : 2397-2399, 1983

      7 Selhub, J., "Homocysteine metabolism" 19 : 217-246, 1999

      8 Barak, A.J., "Dietary Betaine Promotes Generation of Hepatic SAdenosylmethionine and Protects the Liver from Ethanol-Induced Fatty Infiltration" 17 : 552-555, 1993

      9 Shin, Y.G., "Determination of betaine in Lycium chinense fruits by liquid chromatography-electrospray ionization mass spectrometry" 857 : 331-335, 1999

      10 Junnila, M., "Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats" 40 : 263-266, 1998

      1 Noguchi, M., "Uber die Bestandteile der chinesischen Droge Ti-ku-'pi.I. Isolierung und Konstitution von Lyciumamid, einem neuen Dipeptid" 32 : 3584-3587, 1984

      2 Gahl, W.A., "The effect of oral betaine on vertebral body bone density in pyridoxine-nonresponsive homocystinuria" 11 : 291-298, 1988

      3 Murakami, T., "The Recovering Effect of Betaine on Carbon Tetrachloride-Induced Liver Injury" 44 : 249-255, 1998

      4 Funayama, S., "Structure of kukoamine A, a hypotensive principle of Lycium chinense root barks1" 21 : 1355-1356, 1980

      5 Kikuchi, N., "Separation and determination of betaine in an oriental medicine by liquid chromatography" 283 : 338-343, 1993

      6 Sannai, A., "Neutral Volatile Components of "Kukoshi" (Lycium chinense M.)" 47 : 2397-2399, 1983

      7 Selhub, J., "Homocysteine metabolism" 19 : 217-246, 1999

      8 Barak, A.J., "Dietary Betaine Promotes Generation of Hepatic SAdenosylmethionine and Protects the Liver from Ethanol-Induced Fatty Infiltration" 17 : 552-555, 1993

      9 Shin, Y.G., "Determination of betaine in Lycium chinense fruits by liquid chromatography-electrospray ionization mass spectrometry" 857 : 331-335, 1999

      10 Junnila, M., "Betaine reduces hepatic lipidosis induced by carbon tetrachloride in Sprague-Dawley rats" 40 : 263-266, 1998

      11 Wendel, U, "Betaine in the treatment of homocystinuria due to 5,10-methylenetetrahydrofolate reductase deficiency" 142 : 147-150, 1984

      12 Yang, L.L., "Antihepatotoxic actions of formosan plant drugs" 19 : 103-110, 1987

      13 Mar, M.H., "A method for the determination of betaine in tissues using high performance liquid chromatography" 6 : 392-398, 1995

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2011-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2009-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2005-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.18 0.18 0.16
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.15 0.15 0.359 0.02
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