Presence of Metabolic Syndrome Components Is Associated with Tooth Loss in Middle-Aged Adults

다국어 초록 (Multilingual Abstract)

Purpose: In general, the prevalence of metabolic syndrome (MS) and tooth loss increases with age. We investigated the relationshipbetween the presence of MS, its elements, and tooth loss in middle-aged Korean adults.
Materials and Methods: This study included Korean adults between 30 and 64 years of age who resided in the capital area of Seoul.
From January to June 2014, individuals interested in participating in the oral health survey among those who visited the universityhospital’s cardiovascular center and provided informed consent were selected. Among 748 subjects who responded to the oralhealth questionnaires, 30 were excluded due to unclear responses; therefore, a total of 718 were included in the final analysis.
Results: The crude odds ratio (OR) of ≥one MS component affecting tooth loss was 1.45 [95% confidence interval (CI), 1.06–2.00].
After adjusting for sex, age, education, income level, occupation, smoking status, kidney disease, chronic obstructive pulmonarydisease, and rheumatic disease, the adjusted OR was 1.47 (95% CI, 1.06–2.05), which was statistically significant (p<0.05). The ORfor tooth loss was higher in the presence of ≥one component of MS (50–64 years of age) in females.
Conclusion: This study suggests that female aged 50–64 years may have higher likelihood of tooth loss upon the presence of atleast one MS component. Prevention against MS among female of older age could contribute to maintenance of remaining teeth.
Further well-designed studies are needed.

참고문헌 (Reference)

1 박영애, "포항시 일부지역 노인의 전신건강 및 식생황 습관과 구강건강과의 관련성" 대한예방치과·구강보건학회 30 (30): 183-192, 2006

2 진혜정, "치주질환상태 측정을 위한 자기기입식 설문도구의 타당성과 신뢰성" 대한예방치과·구강보건학회 38 (38): 170-175, 2014

3 나대웅, "중년 남성에서 대사증후군과 식이요인과의 관련성" 한국농촌의학.지역보건학회 35 (35): 383-394, 2010

4 강현주, "중⋅노년의 대사증후군과 구강질환 관련성" 한국치위생학회 15 (15): 947-961, 2015

5 조민정, "대사증후군과 자기기입식 설문도구를 이용한 치주건강의 관련성" 대한예방치과·구강보건학회 40 (40): 231-237, 2016

6 강현주, "대사증후군 환자의 치주질환과 치아상실에 관한 연구" 한국치위생과학회 15 (15): 445-456, 2015

7 송선옥, "Trends in Diabetes Incidence in the Last Decade Based on Korean National Health Insurance Claims Data" 대한내분비학회 31 (31): 292-299, 2016

8 McFall WT Jr, "Tooth loss in 100 treated patients with periodontal disease. A long-term study" 53 : 539-549, 1982

9 Furuta M, "Tooth loss and metabolic syndrome in middle-aged Japanese adults" 43 : 482-491, 2016

10 Kim SW, "Tooth loss and metabolic syndrome in South Korea: The 2012 Korean National Health and Nutrition Examination Survey" 95 : e3331-, 2016

11 Gurav AN, "The association of periodontitis and metabolic syndrome" 11 : 1-10, 2014

12 Ojima M, "Relationship Between Decayed Teeth and Metabolic Syndrome : Data From 4716 Middle-Aged Male Japanese Employees" 25 : 204-211, 2015

13 Arai H, "Prevalence of the metabolic syndrome in elderly and middle-aged Japanese" 1 : 42-47, 2010

14 Joshipura KJ, "Poor oral health and coronary heart disease" 75 : 1631-1636, 1996

15 Cairo F, "Periodontal variables may predict sub-clinical atherosclerosis and systemic inflammation in young adults. A cross-sectional study" 2 : 125-133, 2009

16 Khader Y, "Periodontal status of patients with metabolic syndrome compared to those without metabolic syndrome" 79 : 2048-2053, 2008

17 Nishimura F, "Periodontal disease as part of the insulin resistance syndrome in diabetic patients" 7 : 16-20, 2005

18 Loesche WJ, "Periodontal disease as a risk factor for heart disease" 15 : 978-982, 1994

19 Nakarai H, "Periodontal disease and hypertriglyceridemia in Japanese subjects : potential association with enhanced lipolysis" 60 : 823-829, 2011

20 American Academy of Periodontology, "Parameter on systemic conditions affected by periodontal diseases" 71 (71): 880-883, 2000

21 Musskopf ML, "Metabolic syndrome as a risk indicator for periodontal disease and tooth loss" 21 : 675-683, 2017

22 Kaye EK, "Metabolic syndrome and periodontal disease progression in men" 95 : 822-828, 2016

23 Ford ES, "Metabolic syndrome and health-related quality of life among U.S. adults" 18 : 165-171, 2008

24 Laaksonen DE, "Metabolic syndrome and development of diabetes mellitus : application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study" 156 : 1070-1077, 2002

25 Ministry of Health and Welfare, Korea Centers for Disease Control and Preventive, "Korea Health Statistics 2015: Korean National Health and Nutritional Examination survey (KNHANES VI-3)" Ministry of Health and Welfare 298-, 2015

26 National Health Insurance, "Health Insurance Review & Assesment Service"

27 Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults, "Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)" 285 : 2486-2497, 2001

28 Sheiham A, "Evaluation of social and psychological factors in periodontal disease" 39 : 118-131, 2005

29 Casanova L, "Diabetes and periodontal disease : a two-way relationship" 217 : 433-437, 2014

30 Primeau V, "Characterizing the profile of obese patients who are meta-bolically healthy" 35 : 971-981, 2011

31 심지선, "Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) cohort: study protocol and results of the first 3 years of enrollment" 한국역학회 39 : 1-9, 2017

32 Wakai K, "Associations of medical status and physical fitness with periodontal disease" 26 : 664-672, 1999

33 Zhu Y, "Associations between the number of natural teeth and metabolic syndrome in adults" 42 : 113-120, 2015

34 Song IS, "Association between underweight and tooth loss among Korean adults" 7 : 41524-, 2017

35 Morita T, "A cohort study on the association between periodontal disease and the development of metabolic syndrome" 81 : 512-519, 2010