3년간 치료를 지속한 정신과 외래 노인 환자에서의 다제요법에 관한 연구

다국어 초록 (Multilingual Abstract)

Objective :
The objective of this study was to investigate the prescription trends for elderly psychiatry outpatients at a university hospital.

Methods :
We performed a retrospective study based on medical records. Data on 146 elderly patients (65 years and older) diagnosed with psychiatric disorders according to ICD-10 from January 2005 to March 2008 were collected. Analyses were performed regarding demographic characteristics, prevalence of polypharmacy, and the doses and types of drugs prescribed.

Results :
In 146 subjects, the mean age was 76.14±5.21. More than five types of drugs were prescribed to 49.5% of the patients in 2008. The percentage of stable users (those without changes in the category of polypharmacy for 3 years) was 69.8%. Each patient received an average of 4.20±1.50 kinds of drugs in 2005 and 4.02±1.77 in 2008. The average dose of drugs was 6.1±3.50 in 2005 and 6.49±4.09 in 2008, and the difference was not statistically significant. The average number of types of psychiatric drugs prescribed to the patients decreased from 2.37±0.86 in 2005 to 2.17±0.87 in 2008 (p<0.05).

Conclusion :
Although practice of polypharmacy showed a slow increase over the 3 years from 2005 to 2008, almost half of the elderly patients we studied received multiple drugs. Since polypharmacy can increase drug-drug interactions and adverse effects in the elderly, appropriate drug monitoring and careful prescription are necessary.

목차 (Table of Contents)

• 목 차
• Abstract ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ i
• 서론 ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 1
• 연구대상 및 방법 ‥‥‥‥‥‥‥‥‥‥‥‥‥ 7
• 결과 ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 9
• 고찰 ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 13
• 참고문헌 ‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥‥ 30