RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      KCI등재 SCOPUS

      Stem Cell Therapy for Sensorineural Hearing Loss, Still Alive?

      한글로보기

      https://www.riss.kr/link?id=A104756152

      • 0

        상세조회
      • 0

        다운로드
      서지정보 열기
      • 내보내기
      • 내책장담기
      • 공유하기
      • 오류접수

      부가정보

      다국어 초록 (Multilingual Abstract)

      In mammals, the auditory system, which includes the cochlea, has a very complex structure harboring many types of cells performing different functions. Among these cells are the auditory hair cells (HCs), which are terminally and well differentiated unique cells which have lost their regenerative potential after development. The auditory HCs are easily damaged by aging as well as during episodes of ototoxicity and acoustic trauma. HCs damages typically occur in the early stage of injury and can result a permanent hearing loss. Recently, there have been tremendous developments from stem cells (SCs) research involving sensorineural hearing loss, but several limitations and obstacles persist in allowing these developments from continuing onto clinical applications. This review discusses the recent advances in SC research in sensorineural hearing loss with the subsequent sections discussing the possible hurdles and limitations that currently preclude their clinical application.
      번역하기

      In mammals, the auditory system, which includes the cochlea, has a very complex structure harboring many types of cells performing different functions. Among these cells are the auditory hair cells (HCs), which are terminally and well differentiated u...

      In mammals, the auditory system, which includes the cochlea, has a very complex structure harboring many types of cells performing different functions. Among these cells are the auditory hair cells (HCs), which are terminally and well differentiated unique cells which have lost their regenerative potential after development. The auditory HCs are easily damaged by aging as well as during episodes of ototoxicity and acoustic trauma. HCs damages typically occur in the early stage of injury and can result a permanent hearing loss. Recently, there have been tremendous developments from stem cells (SCs) research involving sensorineural hearing loss, but several limitations and obstacles persist in allowing these developments from continuing onto clinical applications. This review discusses the recent advances in SC research in sensorineural hearing loss with the subsequent sections discussing the possible hurdles and limitations that currently preclude their clinical application.

      더보기

      참고문헌 (Reference)

      1 Duan M, "Treatment of peripheral sensorineural hearing loss: gene therapy" 11 (11): S51-S56, 2004

      2 Lang H, "Transplantation of mouse embryonic stem cells into the cochlea of an auditory-neuropathy animal model: effects of timing after injury" 9 : 225-240, 2008

      3 조용범, "Transplantation of Neural Differentiated Human Mesenchymal Stem Cells into the Cochlea of an Auditory-neuropathy Guinea Pig Model" 대한의학회 26 (26): 492-498, 2011

      4 Shibata SB, "Transgenic BDNF induces nerve fiber regrowth into the auditory epithelium in deaf cochleae" 223 : 464-472, 2010

      5 Batts SA, "Transdifferentiation and its applicability for inner ear therapy" 227 : 41-47, 2007

      6 Hildebrand MS, "Survival of partially differentiated mouse embryonic stem cells in the scala media of the guinea pig cochlea" 6 : 341-354, 2005

      7 Han Z, "Survival and fate of transplanted embryonic neural stem cells by Atoh1 gene transfer in guinea pigs cochlea" 21 : 490-496, 2010

      8 Altschuler RA, "Stem cell transplantation for auditory nerve replacement" 242 : 110-116, 2008

      9 Okano T, "Stem cell therapy for the inner ear: recent advances and future directions" 16 : 4-18, 2012

      10 Jongkamonwiwat N, "Stem cell based therapy in the inner ear: appropriate donor cell types and routes for transplantation" 11 : 888-897, 2010

      1 Duan M, "Treatment of peripheral sensorineural hearing loss: gene therapy" 11 (11): S51-S56, 2004

      2 Lang H, "Transplantation of mouse embryonic stem cells into the cochlea of an auditory-neuropathy animal model: effects of timing after injury" 9 : 225-240, 2008

      3 조용범, "Transplantation of Neural Differentiated Human Mesenchymal Stem Cells into the Cochlea of an Auditory-neuropathy Guinea Pig Model" 대한의학회 26 (26): 492-498, 2011

      4 Shibata SB, "Transgenic BDNF induces nerve fiber regrowth into the auditory epithelium in deaf cochleae" 223 : 464-472, 2010

      5 Batts SA, "Transdifferentiation and its applicability for inner ear therapy" 227 : 41-47, 2007

      6 Hildebrand MS, "Survival of partially differentiated mouse embryonic stem cells in the scala media of the guinea pig cochlea" 6 : 341-354, 2005

      7 Han Z, "Survival and fate of transplanted embryonic neural stem cells by Atoh1 gene transfer in guinea pigs cochlea" 21 : 490-496, 2010

      8 Altschuler RA, "Stem cell transplantation for auditory nerve replacement" 242 : 110-116, 2008

      9 Okano T, "Stem cell therapy for the inner ear: recent advances and future directions" 16 : 4-18, 2012

      10 Jongkamonwiwat N, "Stem cell based therapy in the inner ear: appropriate donor cell types and routes for transplantation" 11 : 888-897, 2010

      11 Chen W, "Restoration of auditory evoked responses by human ES-cell-derived otic progenitors" 490 : 278-282, 2012

      12 Izumikawa M, "Response of the flat cochlear epithelium to forced expression of Atoh1" 240 : 52-56, 2008

      13 Li H, "Pluripotent stem cells from the adult mouse inner ear" 9 : 1293-1299, 2003

      14 Vlastarakos PV, "Papacharalambous G, Tzagaroulakis A, Dazert S. Sensory cell regeneration and stem cells: what we have already achieved in the management of deafness" 29 : 758-768, 2008

      15 Parker MA, "Neural stem cells injected into the sound-damaged cochlea migrate throughout the cochlea and express markers of hair cells, supporting cells, and spiral ganglion cells" 232 : 29-43, 2007

      16 Kamiya K, "Mesenchymal stem cell transplantation accelerates hearing recovery through the repair of injured cochlear fibrocytes" 171 : 214-226, 2007

      17 Oshima K, "Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells" 141 : 704-716, 2010

      18 White PM, "Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells" 441 : 984-987, 2006

      19 Lin V, "Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles" 31 : 15329-15339, 2011

      20 Wang Y, "In vitro induction and differentiation of newborn guinea pig hippocampus neural stem cells into cells resembling inner hair cells, using artificial perilymph" 125 : 771-775, 2011

      21 Koehler KR, "Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture" 500 : 217-221, 2013

      22 Li H, "Generation of hair cells by stepwise differentiation of embryonic stem cells" 100 : 13495-13500, 2003

      23 Ishimoto S, "Gene transfer into supporting cells of the organ of Corti" 173 : 187-197, 2002

      24 Matsuoka AJ, "Enhanced survival of bone-marrow-derived pluripotent stem cells in an animal model of auditory neuropathy" 117 : 1629-1635, 2007

      25 Park YH, "Conditioning the cochlea to facilitate survival and integration of exogenous cells into the auditory epithelium" 22 : 873-880, 2014

      26 Izumikawa M, "Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals" 11 : 271-276, 2005

      27 Ulfendahl M, "A cell therapy approach to substitute neural elements in the inner ear" 92 : 75-79, 2007

      더보기

      분석정보

      View

      상세정보조회

      0

      Usage

      원문다운로드

      0

      대출신청

      0

      복사신청

      0

      EDDS신청

      0

      동일 주제 내 활용도 TOP

      더보기

      주제

      연도별 연구동향

      연도별 활용동향

      연관논문

      연구자 네트워크맵

      공동연구자 (7)

      유사연구자 (20) 활용도상위20명

      인용정보 인용지수 설명보기

      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2015-05-22 학술지명변경 한글명 : korean journal of audiology -> Journal of Audiology & Otology KCI등재
      2013-10-01 평가 등재학술지 선정 (기타) KCI등재
      2011-01-01 평가 SCOPUS 등재 (기타) KCI등재후보
      더보기

      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.19 0.19 0.13
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.12 0.12 0.369 0
      더보기

      이 자료와 함께 이용한 RISS 자료

      나만을 위한 추천자료

      해외이동버튼