눈꺼풀의 통증과 발적성 부종을 주소로 내원한 다발성 고립성 형질세포종 1예 = Multiple Solitary Plasmacytomas Presenting with Painful Erythematous Swelling of the Upper Eyelid

다국어 초록 (Multilingual Abstract)

Purpose: To report a case of multiple solitary plasmacytomas that presented with painful erythematous swelling of the upper eyelid. The patient was diagnosed with extramedullary plasmacytoma, and was later found to have multiple metastases of the bone and soft tissue during follow up.
Case summary: A 55-year-old female patient presented with painful erythematous swelling of the left upper eyelid that persisted for 1 month prior to examination. Under suspicion of lacrimal gland inflammation, anti-inflammatory medication was started but the symptoms worsened. Orbital computed tomography showed that a mass infiltrated the left lacrimal gland. We performed incisional biopsy of the mass via eyelid crease incision. Based on histopathological examination, the mass was diagnosed as extramedullary plasmacytoma and the patient was treated with radiation. After a 10-month follow-up period, multiple metastases on the left parotid gland, thoracic spine, lumbar spine and pelvic bone were observed. Finally, we diagnosed the patient with multiple solitary plasmacytomas.
Conclusions: We report the first case of multiple solitary plasmacytomas presenting with upper eyelid painful erythematous swelling. This condition should be considered for patients presenting with eyelid inflammation. In addition, long term follow up should be conducted to detect metastasis or recurrence.

목차 (Table of Contents)

• 증례보고
• 고 찰
• REFERENCES

참고문헌 (Reference)

1 최정기, "안와에서 원발한 골수외 형질세포종" 대한안과학회 44 (44): 30-2923, 2003

2 김국회, "안검의 발적성 부종을 주소로 발견된 안와에 발생한 고립성 골형질세포종 1예" 대한안과학회 48 (48): 731-736, 2007

3 이승준, "눈물배출계에 발생한 골수외 형질세포종 1예" 대한안과학회 56 (56): 427-431, 2015

4 Yang B, "Treatment of multiple solitary plasmacytomas with cytokine-induced killer cells" 16 : 278-284, 2014

5 Koçak E, "Radiation therapy for the solitary plasmacytoma" 27 : 57-61, 2010

6 Lee MS, "Plasmacytoma on the upper cyclid" 37 : 156-161, 1997

7 Dattolo P, "Multiple solitary plasmacytoma with multifocal bone involvement. First clinical case report in a uraemic patient" 2013 : 2013

8 Soutar R, "Guidelines on the diagnosis and management of solitary plasmacytoma of bone and solitary extramedullary plasmacytoma" 124 : 717-726, 2004

9 International Myeloma Working Group, "Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group" 121 : 749-757, 2003

10 Nam KR, "Case report on primary extramedullary plasmacytoma originating in the lacrimal gland" 39 : 771-776, 1998