The prognosis of patients with severe alcoholic hepatitis (AH) remains poor, with a 40% in-hospital mortality rate. Corticosteroids improve the short-term survival of the patients with severe AH. Therefore, it is important to select the subjects who s...
The prognosis of patients with severe alcoholic hepatitis (AH) remains poor, with a 40% in-hospital mortality rate. Corticosteroids improve the short-term survival of the patients with severe AH. Therefore, it is important to select the subjects who should be treated with corticosteroids. Traditionally, the severity of patients with AH has been assessed using Maddrey`s discriminant function (DF). However, the model for end-stage liver disease, the Glasgow alcoholic hepatitis score and ABIC score have been reported to be superior to predict survival than Maddrey`s DF in patients with AH. More recently, the Lille model has shown to have a high sensitivity and specificity in predicting survival at 6 months in patients with AH treated with corticosteroids who do not improve after 7 days of treatment. This review will cover the characteristics of various prognostic models, and the best approach to evaluate the prognosis of patients with AH.