The purpose of this study is to review the role of sirtuin 1 (SIRT1) on the obesity by inflammation Recent data for inflammation, obesity, SIRT1 and exercise were collected from PubMed. Exercise is a powerful physiological activator of SIRT1. The infl...
The purpose of this study is to review the role of sirtuin 1 (SIRT1) on the obesity by inflammation Recent data for inflammation, obesity, SIRT1 and exercise were collected from PubMed. Exercise is a powerful physiological activator of SIRT1. The inflammation regulation mechanism of SIRT1 activation via exercise on the obesity by inflammation are as follows. 1) SIRT1 protein regulation by exercise in obesity model 2) The regulation of inflammation-related genes by SIRT1 via exercise in obesity model. Anti-inflammatory effects of SIRT1 via exercise will be a balancing approach for detrimental effects of obesity and provide fundamental data for the therapy of obesity.