RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      KCI등재

      Inonotus obliquus 액체배양을 통한 균사체 및 다당체 생산을 위한 최적 배양공정 개발

      한글로보기

      https://www.riss.kr/link?id=A105449515

      • 0

        상세조회
      • 0

        다운로드
      서지정보 열기
      • 내보내기
      • 내책장담기
      • 공유하기
      • 오류접수

      부가정보

      다국어 초록 (Multilingual Abstract)

      This study was carried out to investigate the optimum liquid culture conditions for the mycelium and the polysaccharide production on liquid culture of Inonotus obliquus. In flask culture, the production of maximum mycelium and polysaccharide were 9.23 g/L and 1.85 g/L, respectively. In bioreactor, with the culture conditions of agitation rate 200 rpm and aeration rate 1 vvm, the production of mycelium and polysaccharide were 14.17 g/L and 2.81 g/L at the 8<SUP>th</SUP> day of cultivation, respectively. And the cultivation was operated with 300 rpm and 1 vvm up to the 4<SUP>th</SUP> day of cultivation, since then, 200 rpm and 1 vvm, resulting in that the production of mycelium was 15.3 g/L at the 9th day and the polysaccharide production was 2.93 g/L at the 6th day of the cultivation. Furthermore, with the same agitation and aeration rates as the above during the cultivation, the addition of glucose being 20g/L of the final concentration was intermittently accomplished in order to increase the mycelium and the polysaccharide production. As a result, the addition of glucose at the 3<SUP>rd</SUP> day of cultivation resulted in that the maximum mycelium and the polysaccharide production were 17.1 g/L and 3.4 g/L at the 7<SUP>th</SUP> day of cultivation, respectively, indicating that the cultivation period was 4 days shorter than the cultivation of 11 days.
      번역하기

      This study was carried out to investigate the optimum liquid culture conditions for the mycelium and the polysaccharide production on liquid culture of Inonotus obliquus. In flask culture, the production of maximum mycelium and polysaccharide were 9.2...

      This study was carried out to investigate the optimum liquid culture conditions for the mycelium and the polysaccharide production on liquid culture of Inonotus obliquus. In flask culture, the production of maximum mycelium and polysaccharide were 9.23 g/L and 1.85 g/L, respectively. In bioreactor, with the culture conditions of agitation rate 200 rpm and aeration rate 1 vvm, the production of mycelium and polysaccharide were 14.17 g/L and 2.81 g/L at the 8<SUP>th</SUP> day of cultivation, respectively. And the cultivation was operated with 300 rpm and 1 vvm up to the 4<SUP>th</SUP> day of cultivation, since then, 200 rpm and 1 vvm, resulting in that the production of mycelium was 15.3 g/L at the 9th day and the polysaccharide production was 2.93 g/L at the 6th day of the cultivation. Furthermore, with the same agitation and aeration rates as the above during the cultivation, the addition of glucose being 20g/L of the final concentration was intermittently accomplished in order to increase the mycelium and the polysaccharide production. As a result, the addition of glucose at the 3<SUP>rd</SUP> day of cultivation resulted in that the maximum mycelium and the polysaccharide production were 17.1 g/L and 3.4 g/L at the 7<SUP>th</SUP> day of cultivation, respectively, indicating that the cultivation period was 4 days shorter than the cultivation of 11 days.

      더보기

      목차 (Table of Contents)

      • Abstract
      • 1. INTRODUCTION
      • 2. MATERIALS AND METHOD
      • 3. RESULTS AND DISCUSSION
      • 4. CONCLUSION
      • Abstract
      • 1. INTRODUCTION
      • 2. MATERIALS AND METHOD
      • 3. RESULTS AND DISCUSSION
      • 4. CONCLUSION
      • REFERENCES
      더보기

      참고문헌 (Reference)

      1 이학수, "영지의 액체배양 중 균사형태에 미치는 통기 · 교반의 영향 및 Scale-up" 한국생물공학회 26 (26): 357-364, 2011

      2 홍형표, "단백다당체 고생산성의 Inonotus obliquus 균주의 신속 개량을 위한 고체 성장배지의 통계적 최적화" 한국생물공학회 25 (25): 142-154, 2010

      3 Wasser, A. T., "Therapeutic effects of substances occuring on higher basidiomycetes mushrooms: A modern perspective" 19 : 65-96, 1999

      4 Aouadi, S., "Structure and properties of an extracellular polysaccharide from Laetisaria arvalis. Evaluation of its antitumor activity" 16 : 155-165, 1991

      5 Aouadi, S., "Structure and properties of an extracellular polysaccharide from Laetisaria arvalis. Evaluation of its antitumor activity" 16 : 155-165, 1991

      6 Aoki, T., "Staphage lysate and lentinan as immunomodulators and immunopotentiators in clinical and experimental systems" 16 : 101-112, 1981

      7 이종석, "Polysaccharides Isolated from Liquid Culture Broth of Inonotus obliquus Inhibit the Invasion of Human Non-small Cell Lung Carcinoma Cells" 한국생물공학회 22 (22): 45-51, 2017

      8 Lee, K. R., "Polysaccharide isolated from the liquid culture broth of Inonotus obliquus suppresses invasion of B16-F10 melanoma cells via AKT/NF-${\kappa}B$ signaling pathway" 14 : 4429-4435, 2016

      9 Lee, K. R., "Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by supressing MMP-2 and MMP-9 via downregulation of NF-${\kappa}B$ signaling pathway" 31 : 2447-2453, 2014

      10 Borchers, A. T., "Mushrooms, tumors, and immunity" 221 : 281-293, 1999

      1 이학수, "영지의 액체배양 중 균사형태에 미치는 통기 · 교반의 영향 및 Scale-up" 한국생물공학회 26 (26): 357-364, 2011

      2 홍형표, "단백다당체 고생산성의 Inonotus obliquus 균주의 신속 개량을 위한 고체 성장배지의 통계적 최적화" 한국생물공학회 25 (25): 142-154, 2010

      3 Wasser, A. T., "Therapeutic effects of substances occuring on higher basidiomycetes mushrooms: A modern perspective" 19 : 65-96, 1999

      4 Aouadi, S., "Structure and properties of an extracellular polysaccharide from Laetisaria arvalis. Evaluation of its antitumor activity" 16 : 155-165, 1991

      5 Aouadi, S., "Structure and properties of an extracellular polysaccharide from Laetisaria arvalis. Evaluation of its antitumor activity" 16 : 155-165, 1991

      6 Aoki, T., "Staphage lysate and lentinan as immunomodulators and immunopotentiators in clinical and experimental systems" 16 : 101-112, 1981

      7 이종석, "Polysaccharides Isolated from Liquid Culture Broth of Inonotus obliquus Inhibit the Invasion of Human Non-small Cell Lung Carcinoma Cells" 한국생물공학회 22 (22): 45-51, 2017

      8 Lee, K. R., "Polysaccharide isolated from the liquid culture broth of Inonotus obliquus suppresses invasion of B16-F10 melanoma cells via AKT/NF-${\kappa}B$ signaling pathway" 14 : 4429-4435, 2016

      9 Lee, K. R., "Polysaccharide from Inonotus obliquus inhibits migration and invasion in B16-F10 cells by supressing MMP-2 and MMP-9 via downregulation of NF-${\kappa}B$ signaling pathway" 31 : 2447-2453, 2014

      10 Borchers, A. T., "Mushrooms, tumors, and immunity" 221 : 281-293, 1999

      11 Hirokazu, K., "Isolation and properties of a lectin from the fruiting bodies of Agaricus blazei" 183 : 150-154, 1988

      12 Dong Pil Won, "Immunostimulating Activity by Polysaccharides Isolated from Fruiting Body of Inonotus obliquus" 한국분자세포생물학회 31 (31): 165-173, 2011

      13 Lee, J. S., "Hericium erinaceus enhances doxorubicin-induced apoptosis in human hepatocellular carcinoma cells" 297 : 144-154, 2010

      14 Sasaki, T., "Further study of the structure of lentinan, an anti-tumor polysaccharide from Lentinus edodes" 47 : 99-104, 1975

      15 Chihara, G., "Fraction of the polysaccharide with antitumor activity, especially lentinan, from the Lentinus edodes (Berk) Sing. (an edible mushroom)" 30 : 2776-2781, 1970

      16 Araki, A., "Enhancement of polymorphonuclear leukocyte-mediated tumor cytotoxicity by serum factors" 81 : 69-78, 1990

      17 Sim, Y. C., "Effects of polysaccharides isolated from Inonotus obliquus against hydrogen peroxide induced oxidative damage in RINm5F pancreatic beta-cells" 14 : 4263-4270, 2016

      18 Lawford, H., "Effect of oxygen on the rate of ${\beta}$-1,3-glucan microbial exopolysaccharide production" 11 : 125-130, 1989

      19 Liuping F., "Antitumor and immunomodulatory activity of water-soluble polysaccharide from Inonotus obliquus" 90 : 870-874, 2012

      20 Lee, S. H., "Antitumor activity of water extract of a mushroom, Inonotus obliquus, against HT-29 human colon cancer cells" 23 : 1784-1789, 2009

      21 Menoli, M., "Antimutagenic effects of the mushroom Agaricus blazei Murill extracts on V79 cells" 496 : 5-13, 2001

      22 정미자, "Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells" 한국영양학회 4 (4): 177-182, 2010

      23 Kim, Y. O., "Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus" 77 : 2438-2456, 2006

      더보기

      동일학술지(권/호) 다른 논문

      분석정보

      View

      상세정보조회

      0

      Usage

      원문다운로드

      0

      대출신청

      0

      복사신청

      0

      EDDS신청

      0

      동일 주제 내 활용도 TOP

      더보기

      주제

      연도별 연구동향

      연도별 활용동향

      연관논문

      연구자 네트워크맵

      공동연구자 (7)

      유사연구자 (20) 활용도상위20명

      인용정보 인용지수 설명보기

      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2022 평가예정 재인증평가 신청대상 (재인증)
      2019-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2016-01-01 평가 등재학술지 선정 (계속평가) KCI등재
      2015-12-01 평가 등재후보로 하락 (기타) KCI등재후보
      2011-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2009-08-28 학술지명변경 한글명 : 한국생물공학회지 -> KSBB Journal
      외국어명 : Korean Journal of Biotechnology and Bioengineering -> Korean Society for Biotechnology and Bioengineering Journal
      KCI등재
      2009-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2007-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2005-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2002-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      1999-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
      더보기

      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.37 0.37 0.38
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.37 0.36 0.662 0.02
      더보기

      이 자료와 함께 이용한 RISS 자료

      나만을 위한 추천자료

      해외이동버튼