규폐결핵 3례의 임상 및 병리학적 소견의 비교 검토 = The Comparative Study of Three Cases of Silicotuberculosis

다국어 초록 (Multilingual Abstract)

Among the pneumoconiosis, the silicosis is an occupational lung disease, ordinally due to prolonged inhalation of air containing free silicon dioxide.
We had chance to perform autopsy of three cases of silicotuberculosis. Both lungs with hard and contracted appearance, were showed massive fibrous adhesion to pleura and also revealed gritty appearance on cut sectioning, and the cut surfaces were shown dark greenish to black pigmentation.
Characteristically, many dense black or grey colored silicotic nodules measuring upto 1-4 mm in diameter, with anthracotic pigments distributed throughout both lung parenchyma especially along the peribronchial regions in all three cases, commonly.
Microscopically, the nodules were noted as the mass of concentrically laminated dense fibrotic tissue. In addition to those findings, the pulmonary parenchymas were replaced by wide areas of fibrosis and also accompanied with exudative and productive form of tuberculosis (common in all three cases), bronchopneumonia (except case-1) and also compensating emphysema, atelectatic lesions.
At the peripheral areas of the silicotic nodules, focal accumulation of the plasma cells, lymphocytes and many foci of endarteritis were shown in three cases, commonly.
The silica was confirmed by polarizing microscopy as birefringent, white colored crystals.