Hydration Effect on the Intrinsic Magnetism of Natural Deoxyribonucleic Acid as Studied by EMR Spectroscopy and SQUID Measurements

다국어 초록 (Multilingual Abstract)

The hydration effect on the intrinsic magnetism of natural salmon double-strand DNA was explored using electron magnetic resonance (EMR) spectroscopy and superconducting quantum interference device (SQUID) magnetic measurements. We learned from this study that the magnetic properties of DNA are roughly classified into two distinct groups depending on their water content: One group is of higher water content in the range of 2.6-24 water molecules per nucleotide (wpn), where all the EMR parameters and SQUID susceptibilities are dominated by spin species experiencing quasi one-dimensional diffusive motion and are independent of the water content. The other group is of lower water content in the range of 1.4-0.5 wpn. In this group, the magnetic properties are most probably dominated by cyclotron motion of spin species along the helical π -way, which is possible when the momentum scattering time (τ k) is long enough not only to satisfy the cyclotron resonance condition (ωcτ k > 1) but also to induce a constructive interference between the neighboring double helices. The same effect is reflected in the S-shaped magnetization-magnetic field strength (M-H) curves superimposed with the linear background obtained by SQUID measurements, which leads to larger susceptibilities at 1000 G when compared with the values at 10,000 G. In particular, we propose that the spin-orbital coupling and Faraday's mutual inductive effect can be utilized to interpret the dimensional crossover of spin motions from quasi 1D in the hydrate state to 3D in the dry state of dsDNA.

참고문헌 (Reference)

1 Watanuki, A., 63 : 419-, 2006

2 Santos, H. D. L., 35 : 1972-, 1988

3 Steckl, A., 1 : 3-, 2007

4 Bliumenfeld, L. A., 4 : 515-, 1959

5 Shulman, R. G., 5 : 52-, 1961

6 Walsh Jr, W. M., 16 : 1041-, 1961

7 Nakamae, S., 94 : 248102-, 2005

8 Mizoguchi, K., 72 : 033106-, 2005

9 Lee, C. H., 73 : 224417-, 2006

10 Mirkin, C. A., 382 : 607-, 1996

11 Gazit, E., 274 : 317-, 2007

12 Alivisatos, A. P., 382 : 609-, 1996

13 Park, S. Y., 110 : 12673-, 2006

14 Richter, J., 16 : 157-, 2003

15 Gordy, W., 53 : 751-, 1965

16 Sheng, P. K., 4 : 263-, 1959

17 Muller, A., 4 : 214-, 1961

18 Blois Jr, M. S., 3 : 275-, 1963

19 Mizoguchi, K., 96 : 089801-, 2006

20 Nakamae, S., 96 : 089802-, 2006

21 Franklin, R. E., 6 : 673-, 1953

22 O'Brien, F. E. M., 25 : 73-, 1948

23 Lee, S. L., 108 : 3098-, 2004

24 Tinkham, M., 97 : 951-, 1954

25 Yagi, M., 33 : 152-, 2004

26 Shields, H., 45 : 269-, 1959

27 Ehrenberg, A., 157 : 1317-, 1967

28 Iiyama, T., 8 : 135-, 2003

29 Castner, T., 32 : 668-, 1960

30 Kliava, J., 134 : 411-, 1986

31 Warman, J. M., 249 : 319-, 1996

32 Briman, M., 4 : 733-, 2004

33 Endres, R. G., 76 : 195-, 2004

34 Kelley, S. O., 283 : 375-, 1999

35 Nunez, M. E., 40 : 12465-, 2001

36 Boon, E. M., 12 : 320-, 2002

37 Delaney, S., 68 : 6475-, 2003

38 Giese, B., 6 : 612-, 2002

39 Okamoto, A., 125 : 5066-, 2003

40 Henderson, P. T., 96 : 8353-, 1999

41 Barnett, R. N., 294 : 567-, 2001

42 Lewis, F. D., 406 : 51-, 2000

43 Lewis, F. D., 126 : 8206-, 2004

44 Mizoguchi, K., 76 : 043801-, 2007

45 Levy, L. P., 189 : 204-, 1993

46 Kasumov, A. Y., 291 : 280-, 2001

47 Tagami, K., 119 : 7491-, 2003

48 Cai, Z. L., 104 : 6942-, 2000

49 Minot, E. D., 428 : 536-, 2004

50 Livolant, F., 21 : 1115-, 1996

51 Smalyukh, I. I., 96 : 177801-, 2006

52 Lorman, V., 87 : 218101-, 2001

53 Manna, F., 75 : 030901(R)-, 2007

54 Kornyshev, A. A., 95 : 148102-, 2005

55 Mesquita, M. V., 102 : 1116-, 2005

56 Sension, R. J., 446 : 740-, 2007

57 Bagguley, D. M. S., 262 : 340-, 1961

58 Bagguley, D. M. S., 262 : 365-, 1961

59 Canali, C., 12 : 2265-, 1975

60 Jacoboni, C., 24 : 1014-, 1981

61 Grote, J. G., 426 : 3-, 2005

62 Herak, J. N. E., "p. r. of Irradiated Single Crystals of the Nucleic Acid Constituents in Physico-chemical Properties of Nucleic Acids, Vol. 1" Academic Press 197-, 1973

63 Cai, Z., "Studies of Excess Electron and Hole Transfer in DNA at Low Temperatures in Long-Range Transfer in DNA II" Springer 103-, 2004

64 Nicolau, C., "Short-lived Free Radicals in Aqueous Solutions of Nucleic Acid Components in Physico-chemical Properties of Nucleic Acids, Vol. 1" Academic Press 143-, 1973

65 Kahn, O., "Molecular Magnetism" VCH 1993

66 Schuster, G. B., "Long-Range Charge Transfer in DNA II" Springer 2004

67 Schuster, G. B., "Long-Range Charge Transfer in DNA I" Springer 2004

68 Kittel, C., "Introduction to Solid State Physics" John Wiley 423-, 1991

69 Jeong-Mi Lee, "Interaction of Ruthenium(II)[(1,10-phenanthroline)2benzodipyrido[3,2-a:2',3'-c]- phenazine]2+ with Single Stranded Poly(dA) and Poly(dT): Turning off the Light Switch" 대한화학회 28 (28): 965-969, 2007

70 Kittel, C., "In Introduction to Solid State Physics" John Wiley 413-, 1991

71 von Sonntag, C., "Free-radical-Induced DNA Damage and Its Repair: A Chemical Perspective" Springer 2006

72 Griffiths, D. J., "Faraday's Law in Introduction to Electrodynamics" Prentice Hall 301-, 1999

73 Heeyoung Kim, "Environment Dependent Coherence of a Short DNA Charge Transfer System" 대한화학회 28 (28): 607-612, 2007

74 Nechtschein, M., "Electron Spin Dynamics in Handbook of Conducting Polymers" Marcel Dekker, Inc 141-, 1998

75 Sevilla, M. D., "ESR Studies of Radiation Damage to DNA and Related Biomolecules in Electron Paramagnetic Resonance. Vol. 19" RSC Publishing 243-, 2004

76 Lax, B., "Cyclotron Resonance in Solid State Physics. Vol. 11" Academic Press 261-, 1960

77 Wagenknecht, H.-A., "Charge Transfer in DNA: From Mechanism to Application" Wiley-VCH 2005

78 Wertz, J. E., "Appendix D Experimental Methods; Spectrometer Performance in Electron Spin Resonance: Elementary Theory and Practical Applications" McGraw-Hill Book Company 450-, 1972