The dermis, as an integral system, contains fibrous matrix, filamentous and diffuse matrix component, cellular component, most importantly fibroblast, and nerve and vascular networks. In this section, these basic constituents of the dermis will be dis...
The dermis, as an integral system, contains fibrous matrix, filamentous and diffuse matrix component, cellular component, most importantly fibroblast, and nerve and vascular networks. In this section, these basic constituents of the dermis will be discussed specifically according to the important articles, which appeared in major dermatological journals from the year 2012 to 2013.The dermis, making up the majority of the skin, has functions such as protection from mechanical injury, binding water, thermal regulation, and sensory, because of its features of pliability, elasticity, and tensile strength. It also has unique interaction with epidermis during development or morphogenesis, maintaining, repairing or remodeling after skin wounds. The dermis is comprised of two major parts, the papillary dermis and the reticular dermis, which defines their characteristic histologic features.