In order to study the effect of extracts of Solanum lyratum Thunberg on the liver damage of the rats intoxicated with CCl^4, the activities of GPT, GOT, Al.P, LDH and the levels of total cholesterol, total bilirubin in serum were measured.
The resul...
In order to study the effect of extracts of Solanum lyratum Thunberg on the liver damage of the rats intoxicated with CCl^4, the activities of GPT, GOT, Al.P, LDH and the levels of total cholesterol, total bilirubin in serum were measured.
The results were as follow:
The extracts (M-Ex, W-Ex.) wee showed to be significanfty decrease in the activities of GPT and GOT in serum rats intoxicated by CCl_4.
The Al.p activity was significantly decreased on the 2nd day after administration of the extracts. The LDH acticity was significantly decreased in all sample groups, but W-Ex was more decreased than M-Ex.
The level of total cholesterol and total bilirubin was showed to be signicantly decreased on the 2nd and 4th days after administration of M-Ex., but W-Ex. was not influenced, when copared with control group.
Acording to the above results, it is thought that the extract of Solanum lyratum improves the hepatic function in the CCl_4-infoxicated rats.