Recent trends in diagnostic techniques for inflammatory bowel disease

다국어 초록 (Multilingual Abstract)

Although ileocolonoscopy is the gold standard for diagnosis of inflammatory bowel disease and is useful for assessing the disease severity in the colon and terminal ileum, several alternative diagnostic techniques have been developed recently. For ulcerative colitis (UC), magnification colonoscopy, endocytoscopy, and confocal laser endomicroscopy enable assessment of histological inflammation without the need for biopsy. Capsule endoscopy is useful for detection of small intestinal and colonic lesions in both female and male patients. For UC, capsule endoscopy may be useful for evaluating colonic inflammation in patients with a previous poor colonoscopy experience, while it should be used only in Crohn’s disease (CD) patients with unexplained symptoms when other examinations are negative. Magnetic resonance enterography (MRE) is particularly useful for detecting transmural inflammation, stenosis, and extraintestinal lesions, including abscesses and fistulas. MRE is also useful when evaluating small and large intestinal lesions, even in cases with severe strictures in which full evaluation of the small bowel would be virtually impossible using other devices. Therefore, the appropriate diagnostic devices for detecting CD lesions in the small and large intestine should be used.

참고문헌 (Reference)

1 Iddan G, "Wireless capsule endoscopy" 405 : 417-, 2000

2 Cotter J, "Validation of the Lewis score for the evaluation of small-bowel Crohn’s disease activity" 47 : 330-335, 2015

3 Yamamoto H, "Total enteroscopy with a nonsurgical steerable double-balloon method" 53 : 216-220, 2001

4 Sung J, "The use of Pillcam Colon in assessing mucosal inflammation in ulcerative colitis: a multicenter study" 44 : 754-758, 2012

5 de Melo SW Jr, "The role of capsule endoscopy in evaluating inflammatory bowel disease" 41 : 315-323, 2012

6 Panes J, "Systematic review:the use of ultrasonography, computed tomography and magnetic resonance imaging for the diagnosis, assessment of activity and abdominal complications of Crohn’s disease" 34 : 125-145, 2011

7 Kopylov U, "Small bowel capsule endoscopy in the management of established Crohn’s disease: clinical impact, safety, and correlation with inflammatory biomarkers" 21 : 93-100, 2015

8 Tielbeek JA, "Serial magnetic resonance imaging for monitoring medical therapy effects in Crohn’s disease" 19 : 1943-1950, 2013

9 Niv E, "Sequential capsule endoscopy of the small bowel for follow-up of patients with known Crohn’s disease" 8 : 1616-1623, 2014

10 Spada C, "Second-generation colon capsule endoscopy compared with colonoscopy" 74 : 581.e1-589.e1, 2011

11 Bourreille A, "Role of small-bowel endoscopy in the management of patients with inflammatory bowel disease: an international OMED-ECCO consensus" 41 : 618-637, 2009

12 Travis SP, "Reliability and initial validation of the ulcerative colitis endoscopic index of severity" 145 : 987-995, 2013

13 Siddiki HA, "Prospective comparison of state-of-the-art MR enterography and CT enterography in small-bowel Crohn’s disease" 193 : 113-121, 2009

14 Fiorino G, "Prospective comparison of computed tomography enterography and magnetic resonance enterography for assessment of disease activity and complications in ileocolonic Crohn’s disease" 17 : 1073-1080, 2011

15 Bessissow T, "Prognostic value of serologic and histologic markers on clinical relapse in ulcerative colitis patients with mucosal healing" 107 : 1684-1692, 2012

16 Ye CA, "PillCam colon capsule endoscopy versus conventional colonoscopy for the detection of severity and extent of ulcerative colitis" 14 : 117-124, 2013

17 Kruis W, "Once daily versus three times daily mesalazine granules in active ulcerative colitis: a double-blind, double-dummy, randomised, non-inferiority trial" 58 : 233-240, 2009

18 Tsujikawa T, "Novel single-balloon enteroscopy for diagnosis and treatment of the small intestine: preliminary experiences" 40 : 11-15, 2008

19 Neumann H, "New endoscopic approaches in IBD" 17 : 63-68, 2011

20 Ardizzone S, "Mucosal healing predicts late outcomes after the first course of corticosteroids for newly diagnosed ulcerative colitis" 9 : 483.e3-489.e3, 2011

21 Florholmen J., "Mucosal healing in the era of biologic agents in treatment of inflammatory bowel disease" 50 : 43-52, 2015

22 Neurath MF, "Mucosal healing in inflammatory bowel diseases: a systematic review" 61 : 1619-1635, 2012

23 Froslie KF, "Mucosal healing in inflammatory bowel disease:results from a Norwegian population-based cohort" 133 : 412-422, 2007

24 Usui S, "Modified bowel preparation regimen for use in second-generation colon capsule endoscopy in patients with ulcerative colitis" 26 : 665-672, 2014

25 Spada C, "Meta-analysis shows colon capsule endoscopy is effective in detecting colorectal polyps" 8 : 516-522, 2010

26 Kunihiro M, "Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation" 10 : 737-744, 2004

27 Naganuma M, "Magnetic resonance enterography of Crohn’s disease" 9 : 37-45, 2015

28 Naganuma M, "Inflammatory bowel disease and novel endoscopic technologies" 26 (26): 20-28, 2014

29 Hurlstone DP, "High-magnification chromoscopic colonoscopy in ulcerative colitis: a valid tool for in vivo optical biopsy and assessment of disease extent" 38 : 1213-1217, 2006

30 Eliakim R, "Evaluation of the PillCam Colon capsule in the detection of colonic pathology: results of the first multicenter, prospective, comparative study" 38 : 963-970, 2006

31 Oshitani N, "Evaluation of deep small bowel involvement by double-balloon enteroscopy in Crohn’s disease" 101 : 1484-1489, 2006

32 Van Assche G, "Effects of infliximab therapy on transmural lesions as assessed by magnetic resonance enteroclysis in patients with ileal Crohn’s disease" 7 : 950-957, 2013

33 Colombel JF, "Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis" 141 : 1194-1201, 2011

34 Jensen MD, "Diagnostic accuracies of MR enterography and CT enterography in symptomatic Crohn’s disease" 46 : 1449-1457, 2011

35 Gralnek IM, "Development of a capsule endoscopy scoring index for small bowel mucosal inflammatory change" 27 : 146-154, 2008

36 Mary JY, "Development and validation of an endoscopic index of the severity for Crohn’s disease:a prospective multicentre study: Groupe d’Etudes Therapeutiques des Affections Inflammatoires du Tube Digestif (GETAID)" 30 : 983-989, 1989

37 Daperno M, "Development and validation of a new, simplified endoscopic activity score for Crohn’s disease: the SES-CD" 60 : 505-512, 2004

38 Travis SP, "Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS)" 61 : 535-542, 2012

39 Hanauer SB, "Delayed-release oral mesalamine at 4.8 g/day (800 mg tablet) for the treatment of moderately active ulcerative colitis: the ASCEND II trial" 100 : 2478-2485, 2005

40 Lee SS, "Crohn disease of thesmall bowel: comparison of CT enterography, MR enterography, and small-bowel follow-through as diagnostic techniques" 251 : 751-761, 2009

41 Bessho R, "Correlation between endocytoscopy and conventional histopathology in microstructural features of ulcerative colitis" 46 : 1197-1202, 2011

42 Takenaka K, "Comparison of magnetic resonance and balloon enteroscopic examination of the small intestine in patients with Crohn’s disease" 147 : 334.e3-342.e3, 2014

43 Spada C, "Colon capsule endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline" 44 : 527-536, 2012

44 Meister T, "Colon capsule endoscopy versus standard colonoscopy in assessing disease activity of ulcerative colitis: a prospective trial" 17 : 641-646, 2013

45 Schroeder KW, "Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study" 317 : 1625-1629, 1987

46 Yamamoto H, "Clinical outcomes of double-balloon endoscopy for the diagnosis and treatment of small-intestinal diseases" 2 : 1010-1016, 2004

47 Li CQ, "Classification of inflammation activity in ulcerative colitis by confocal laser endomicroscopy" 105 : 1391-1396, 2010

48 Kiesslich R, "Chromoscopy-guided endomicroscopy increases the diagnostic yield of intraepithelial neoplasia in ulcerative colitis" 132 : 874-882, 2007

49 Herfarth HH, "Capsule and balloon endoscopy:When are they really needed in patients with inflammatory bowel diseases?" 28 : 439-444, 2010

50 Gal E, "Assessment and validation of the new capsule endoscopy Crohn’s disease activity index (CECDAI)" 53 : 1933-1937, 2008

51 Hosoe N, "Applicability of second-generation colon capsule endoscope to ulcerative colitis: a clinical feasibility study" 28 : 1174-1179, 2013

52 Herrerias JM, "Agile patency system eliminates risk of capsule retention in patients with known intestinal strictures who undergo capsule endoscopy" 67 : 902-909, 2008

53 Ordas I, "Accuracy of magnetic resonance enterography in assessing response to therapy and mucosal healing in patients with Crohn’s disease" 146 : 374.e1-382.e1, 2014

54 D’Haens G, "A review of activity indices and efficacy end points for clinical trials of medical therapy in adults with ulcerative colitis" 132 : 763-786, 2007