Compressibility of woven textiles on the architecture of a highly ordered cylindrical, orthogonal, hollow‐channeled scaffolds

다국어 초록 (Multilingual Abstract)

Scaffolds that mimic the architecture of native tissues are highly desirable for tissue engineering. Because some human tissues, such as nerves and teeth, have an oriented microscale structure, the control of the scaffold design parameters is important. In this study, we fabricated micro‐oriented structures with different interpenetrating networks by combining thermal compression, sintering, solvent casting, and particulate leaching techniques. The influence of the processing parameters, such as the compaction pressure, number of stacked fabric layers, and compression time on the structure, pore morphology, porosity, and thickness was studied. Increases in the compacting pressure resulted in changes in the pores morphology; when the pores changed from circular to elliptical cylindrical channels, the porosity reached its maximum. A further increase in the pressure resulted in a slight decrease in the porosity because of the collapse of the elliptical cylindrical channels and the shift in the pore channels from orthogonal assembly to lamellar structure. On the other hand, the scaffold thickness could be controlled by the adjustment of the compaction pressure and/or the number of stacked fabric layers. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44616.