정지신호과제의 수행이 동작의 실행과 정지기능에 미치는 영향 = The Effect of Performance of a Stop Signal Task on the Execution and Stop Function of Movement

다국어 초록 (Multilingual Abstract)

Purpose: We studied the changes in motor response time and stop signal response time following visuomotor skill learning of a stop signal task in young healthy subjects. This study also was designed to determine what an effective practice is for different stop signals in the stop signal task (SST). Methods: Forty-five right-handed normal volunteers without a history of neurological dysfunction were recruited. They all gave written informed consent. In all subjects, motor reaction time (RT) and stop signal reaction time (SSRT) were measured for the stop signal task. Tasks were classified into three categories: predictable-stop signal task (P-SST) practice group random-stop signal task (R-SST) practice group control group. Results: Motor reaction time in the P-SST was significantly reduced when comparing pre- and post-tests (p<0.05). Stop signal reaction times in the P-SST and the R-SST were significantly reduced following motor skill learning (p<0.05). Also, the reaction time of the R-SST was shorter than that of the P-SST. Conclusion: These findings indicate that practice of an SST improves motor performance and stop function for some stop signals in the SST. P-SST practice was effective in the stop function of regular movement because of faster of the motor prediction and preparation but the R-SST was effective in the stop function of movements because of faster motor selection.

참고문헌 (Reference)

1 이미영, "아급성기 뇌졸중 환자에서 지각-운동 과제를 통한 내잠 학습의 효과" 대한물리치료학회 20 (20): 1-8, 2008

2 원주영, "멈춤 신호 과제의 타당화 연구" 한국심리학회 27 (27): 217-234, 2008

3 Miyake A, "The unity and diversity of executive functions and their contributions to complex "Frontal lobe" Tasks: A latent variable analysis" 41 (41): 49-100, 2000

4 Aron AR, "The neural basis of inhibition in cognitive control" 13 (13): 214-228, 2007

5 Seiss E, "The basal ganglia and inhibitory mechanisms in response selection: Evidence from subliminal priming of motor responses in parkinson's disease" 127 (127): 330-339, 2004

6 van den Wildenberg WP, "Stimulation of the subthalamic region facilitates the selection and inhibition of motor responses in parkinson's disease" 18 (18): 626-636, 2006

7 Verbruggen F, "Selective stopping in task switching: The role of response selection and response execution" 53 (53): 48-57, 2006

8 Rubia K, "Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex is responsible for error detection" 20 (20): 351-358, 2003

9 Verbruggen F, "Response inhibition in the stop-signal paradigm" 12 (12): 418-424, 2008

10 Enticott PG, "Response inhibition and impulsivity in schizophrenia" 157 (157): 251-254, 2008

11 Jahfari S, "Responding with restraint: What are the neurocognitive mechanisms" 22 (22): 1479-1492, 2009

12 Verbruggen F, "Proactive adjustments of response strategies in the stop-signal paradigm" 35 (35): 835-854, 2009

13 Chikazoe J, "Preparation to inhibit a response complements response inhibition during performance of a stop-signal task" 29 (29): 15870-15877, 2009

14 Nigg JT, "Poor response inhibition as a predictor of problem drinking and illicit drug use in adolescents at risk for alcoholism and other substance use disorders" 45 (45): 468-475, 2006

15 Logan GD, "On the ability to inhibit thought and action: A user's guide to the stop signal paradigm" Academic Press 1994

16 Goudriaan AE, "Neurocognitive functions in pathological gambling: A comparison with alcohol dependence, tourette syndrome and normal controls" 101 (101): 534-547, 2006

17 Chamberlain SR, "Motor inhibition and cognitive flexibility in obsessive-compulsive disorder and trichotillomania" 163 (163): 1282-1284, 2006

18 Verbruggen F, "Models of response inhibition in the stop-signal and stop-change paradigms" 33 (33): 647-661, 2009

19 Rieger M, "Inhibition of ongoing responses following frontal, nonfrontal, and basal ganglia lesions" 17 (17): 272-282, 2003

20 Seger CA, "Implicit learning" 115 (115): 163-196, 1994

21 Band GP, "Horse-race model simulations of the stop-signal procedure" 112 (112): 105-142, 2003

22 Claffey MP, "Having a goal to stop action is associated with advance control of specific motor representations" 48 : 541-548, 2010

23 Li CS, "Gender differences in cognitive control: An extended investigation of the stop signal task" 3 (3): 262-276, 2009

24 van der Schoot M, "Effects of stop signal modality, stop signal intensity and tracking method on inhibitory performance as determined by use of the stop signal paradigm" 46 (46): 331-341, 2005

25 Chevrier AD, "Dissociation of response inhibition and performance monitoring in the stop signal task using event-related fmri" 28 (28): 1347-1358, 2007

26 Bekker EM, "Disentangling deficits in adults with attention-deficit/hyperactivity disorder" 62 (62): 1129-1136, 2005

27 Monterosso JR, "Deficits in response inhibition associated with chronic methamphetamine abuse" 79 (79): 272-277, 2005

28 Aron AR, "Cortical and subcortical contributions to stop signal response inhibition: Role of the subthalamic nucleus" 26 (26): 2424-2433, 2006

29 Duncan J, "Common regions of the human frontal lobe recruited by diverse cognitive demands" 23 (23): 475-483, 2000

30 Barkley RA, "Behavioral inhibition, sustained attention, and executive functions: Constructing a unifying theory of adhd" 121 (121): 65-94, 1997

31 Verbruggen F, "Automaticity of cognitive control: Goal priming in response-inhibition paradigms" 35 (35): 1381-1388, 2009

32 Cohen JR, "Automaticity in motor sequence learning does not impair response inhibition" 15 (15): 108-115, 2008

33 Carter JD, "Assessing inhibitory control: A revised approach to the stop signal task" 6 (6): 153-161, 2003

34 Goghari VM, "3rd. The neural basis of cognitive control: Response selection and inhibition" 71 (71): 72-83, 2009