일부 지역 주민들의 모발 수은 농도와 혈중 수은 농도와의 상관성 = Correlation between Hair Mercury Concentration and Blood Total Mercury in Several Area Residents

다국어 초록 (Multilingual Abstract)

Background: This study was carried out for the purpose of comprehensively evaluating the mercury exposure level of residents in several areas and the correlation between hair mercury concentration and blood mercury concentration. Method: One thousand one hundred ninety seven subjects were sampled from 30 sites using random assignment sampling. We performed a questionnaire survey and measured the level of total mercury in hair and blood samples from all subjects. Results: The geometric mean concentrations of hair and blood mercury in all subjects were 1.27 mg/kg [95% confidence interval (CI): 1.23-1.32 mg/kg] and 5.24 ${\mu}g/L$ [95% CI: 5.07-5.41 ${\mu}g/L$], respectively. Male (1.56 mg/kg in hair, 6.00 ${\mu}g/L$ in blood) was significantly higher than that of female (1.03 mg/kg in hair, 4.56 ${\mu}g/L$ in blood), and the concentrations were elevated as age increased up to the 50s. Education, smoking, alcohol drinking, and using of pesticides were also shown to influence mercury concentrations in hair and blood. The ratio of hair/ blood mercury concentration was 261.3. The total mercury concentration in hair was identified to be significantly related with total mercury concentration in blood (r=0.814, p<0.001). Conclusion: The geometric mean concentrations of hair and blood mercury were higher than the levels provided in international recommendations. The total mercury concentration in hair was positively correlated with the concentration in blood. The results of this study suggest that hair mercury be considered as a useful tool for the evaluation of mercury exposure.

참고문헌 (Reference)

1 호문기, "혈 중 수은 농도와 건강 및 생활요인과의 관련성" 환경독성보건학회 21 (21): 2006

2 송미라, "전남지역 일부 대학생 모발 중 수은 농도에 관한 연구" 한국환경보건학회 35 (35): 287-294, 2009

3 김근배, "국내 초등학생의 체내 총수은 농도 및 노출요인 조사" 한국환경보건학회 33 (33): 386-391, 2007

4 US EPA, "Wter Quality Criterion for the Protection of Hman Health: Methylmercury" US EPA 2001

5 Kershaw TG, "The relationship between blood levels and does of methyl mercury in men" 35 : 28-35, 1980

6 Ministry of Environment, "Survey of Blood Heavy Metal Concentration in Koreans" Ministry of Environment 2005

7 Korean Occupational Health Management Association, "Standard of biological exposure indices and analytical methods III: 10 heavy-metal (etc. lead)" KOSHA 2010

8 Jakie Mortonm Vikki A, "Removal of exogenously bound elements from human hair by various washing procedures and determination by inductively coupled plasma mass spectrometry" 455 : 23-34, 2002

9 Yamaguchi S, "Relationship between mercury content of hair and amount of fish consume" 86 : 904-909, 1971

10 Mortada WI, "Reference intervals of cadmium, lead, and mercury im blood, urine, hair, and nails among residents in Mansoura City, Nile Delta, Egypt" 90 (90): 104-110, 2002

11 Putman JJ, "Quicksilver and slow death" 142 (142): 506-527, 1972

12 Airey D., "National fish consumption and the accumulation of nercury in human hair"

13 Bakir F, "Methyl mercury poisoning in Iraq. An inter-university report" 181 : 230-241, 1973

14 Bjornberg KA, "Methyl Mercury and Inorganic Mercury in Swedish Pregnant Women and in Cord Blood: Influence of Fish Consumption" 111 (111): 637-641, 2003

15 US EPA, "Method 7473: Mercury in solids and solutions by thermal decomposition amalgamation, and atomic absorption spectrophotometry" US EPA 2007

16 Suzuki T, "Mercury content of hair of Japanese after emigration to Burma and East Pakistan" 7 : 26-32, 1972

17 Tejning S, "Mercury content of blood corpuscles, blood plasma and hair in heavy fish-eaters from different areas of Lake Venerm and relation between content of fish and a suggestion regarding the international food and health value and its use for fish and fish products" 67 : 8-31, 1967

18 Sivalingam PM, "Mercury content in hair from fishing communities of the state of Penang, Malaysia" 11 : 188-191, 1980

19 Kim YS, "Mercury concentration in pregnant women's hair in the Seoul area" 18 (18): 105-111, 1992

20 Eun JK, "Mercury Contents of Human Scalp Hair by the Consumption Pattern in Fish" 15 (15): 8-14, 2000

21 Phelps RW, "Interrelationships of blood and hair mercury concentrations in a North American population exposed to methylmercury" 35 (35): 161-168, 1980

22 Johnsson C, "Hair mercury levels versus freshwater fish consumption in household members of Swedish angling societies" 96 (96): 257-263, 2004

23 Gonzalez MJ, "Hair mercury levels of residents in China, Indonesiam and Japan" 53 (53): 36-43, 1998

24 WHO, "Environmental Health Criteria 1 : Mercury"

25 Miettinon JK, "Elimination of 203 Hg methyl mercury in man" 3 : 116-122, 1971

26 Miwaco D, "Effects of hair treatment on hair mercury-The best biomarker of methylmercury exposure?" 10 (10): 208-212, 2005

27 Akira Y, "Current Hair Mercury Levels in japanese : Survey in Five Districts" 199 : 161-169, 2003

28 Sakamoto M, "Correlations between mercury concentrations in umbilical cord tissue and other biomarkers of fetal exposure to methylmercury in the Japanese population" 103 (103): 106-111, 2007

29 Koh HS, "Concentration distribution of metals in hairs from runal residents" 18 (18): 1991

30 Vupputuri S, "Blood mercury level and pressure among US women : results from the National Health and Nutrition Examination Survey 1999-2000" 97 (97): 195-200, 2005

31 Schober SE, "Blood Mercury Levels in US Children and Women of Childbearing Age, 1999-2000" 289 (289): 1667-1674, 2003

32 조은미, "Blood Mercury Concentration and Related Factors in an Urban Coastal Area in Korea" 대한예방의학회 43 (43): 377-386, 2010

33 Gompertz D., "Biological monitoring of workers exposed to mercury vapour" 32 (32): 141-145, 1982

34 Budtz-JØrgensen E, "Association between mercury concentrations in blood and hair in methylmercuryexposed subjects at different ages" 95 (95): 385-393, 2004

35 Kwon YT., "A study on the heavy metal content in scalp hair of Korean, Russian, Japanese and American" 12 : 65-77, 1990

36 Kim JH., "A study on concentrations of heavy metals in scalp hair of residents in some area" Korue University 2011

37 Taik SL, "A study of the content of total mercury in the head hair of dental personnel" 23 : 17-29, 1979

38 Park WS, "A Study on the heavy metal contents in human hairs" Kyungnam University 1997

39 Kim HJ, "A Study on the Contents of Heavy Metals in Hairs by Sex and Coloring" 8 (8): 67-74, 2002

40 Lee WK, "A Note on Relationship between Strengths of Heavy Metals Contamination in Scalp Hair and Organs from Autopsy Subjects" 10 (10): 215-222, 1999