원발성 간세포암의 간동맥색전술후 효과와 재발판정에서 혈중 Alpha Fetoprotein(AFP)의 유용성에 관한 고찰 = Usefullness of Alpha-Fetoprotein Assay on the Evaluation of the Effect after Transcatheter Arterial Chemoembolization and Detection of the Recurrence in Patients with Hepatocellular Carcinoma

다국어 초록 (Multilingual Abstract)

The author evaluated the usefulness of alpha-fetoprotein(AFP) in determining the efficacy of transcatheter arterial chemoembolication(TAE) and detection of recurrence in 68 patients with hepatocellular carcinoma(HCC) who were treated by TAE more than two times.
The patients were classified into high AFP goup(AFP≥200ng/ml) and low AFT group (AFP<200ng/ml). The change of AFP was evaluated after first TAE. In 23 patients with recurred HCC, the recurrence was determined by angiography and/or CT. The value of AFT in the detection of recurrence was also estimated in the recurred cases.
In high AFP group, the AFP decreased after the first TAE in 71%(30/42), increased at recurrence in 64%(7/11), and there was positive correlation between changes in the AFT and the findings of imaging diagnosis. In low AFP group, the AFP did not decrease after first TAE in 73%(19/26) and did not increase at recurrence in 50%(6/12).
The AFP value was useful in determining the efficacy of TAE and detection of recurrence in high AFP gorup. But in low AFP group, the value of AFP was limited, and imaging methods were more important.