CELL MORPHOLOGY CHANGE BY THE ULTRAVIOLET RAY IRRADIATION

목차 (Table of Contents)

• 1. INTRODUCTION
• 2. MATERIALS AND METHODS
• 2.1 Cell Sample
• 2.2 Cell Cycle Synchronization
• 2.3. Effect of UVC Irradiation on ADSCs
• 3. RESULTS
• 3.1 Synchronization of Cell Cycle by Serum Starvation
• 3.2 The Effect of UVC Irradiation on ADSCs
• 4. DISCUSSION
• 5. CONCLUSION
• REFERENCES

참고문헌 (Reference)

1 Florence V, "p53- independent regulation of cyclin B1 in normal human fibroblasts during UV-induced G2-arrest" 91 : 665-674, 1999

2 Zhang H, "p53 plays a central role in UVA and UVB induced cell damage and apoptosis in melanoma cells" 244 : 229-238, 2006

3 Katsutoshi K, "XPC lymphoblastoid cells defective in the hMutS DNA mismatch repair complex exhibit normal sensitivity to UVC radiation and normal transcription-coupled excision repair of DNA cyclobutane pyrimidine dimers" 3 : 649-657, 2004

4 Dimri G.P., "What has senescence got to do with cancer?" 7 : 505-512, 2005

5 Enninga IC, "Use of low temperature for growth arrest and synchronization of human diploid fibroblasts" 130 : 343-352, 1984

6 Radziszewska E, "UVC induced cell death of IL-2-dependent human lymphocytes" 23 : 97-103, 1999

7 Tarja H, "UV radiation is a transcriptional inducer of p21Cip1/Waf1 cyclin-kinase inhibitor in a p53- independent manner" 248 : 272-279, 1999

8 Hayflick L, "The limited in vitro lifetime of human diploid cell strains" 37 : 614-636, 1965

9 Moriwaki SI, "The effect of donor age on the processing of UVdamaged DNA by cultured human cells: Reduced DNA repair capacity and increased DNA mutability" 364 : 117-123, 1996

10 Nakayama K, "Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27kip1" 282 : 853-860, 2001

11 Yoshitake M, "Rapid downregulation of cyclin D1 mRNA and protein levels by ultraviolet irradiation in murine macrophage cells" 284 : 71-76, 2001

12 Lodish H, "Molecular cell biology" Tokyo chemical publication 778-781, 2005

13 Bruce A, "Molecular Biology of the cell" Newton publication 984-992, 2004

14 Ide T, "Mechanism of cell proliferation- cell cycle, oncogenes, and senescence" 126 : 1087-1115, 2006

15 Macro M, "Mammalian cell cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6" 118 : 493-504, 2004

16 Milligan A, "Involvement of p16CDKN2A in cell cycle delays after low dose UV irradiation" 422 : 43-53, 1998

17 Mognolia MF, "Inhibition of Toxoplasma gondii growth by pyrrolidine dithiocarbamate is cell cycle specific and leads to population synchronization" 157 : 22-31, 2008

18 Kvam E, "Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation" 18 : 2379-2384, 1997

19 Kang MK, "In vitro replication and differentiation of human oral keratinocytes" 258 : 288-297, 2000

20 Krzysztof K, "Impaired response to oxidative stress in senescent cells may lead to accumulation of DNA damage in mesothelial cells from aged donor" 373 : 335-339, 2008

21 Marcus SC, "Immunodenicity of DNA damaged by reactive oxygen species-implications for anti-DNA antibodies in lupus" 22 : 151-159, 1997

22 Zhang X, "Identification of possible reactive oxygen species involved in ultraviolet radiation-induced oxidative DNA damage" 23 : 980-985, 1997

23 Homma Y, "Evidence for the accumulation of oxidative stress during cellular ageing of human diploid fibroblasts" 203 : 1063-1068, 1994

24 Khammanit R, "Effect of serum starvation and chemical inhibitors on cell cycle synchronization of canine dermal fibroblasts" 70 : 27-34, 2008

25 Perdiz D, "Distribution and Repair of Bipyrimidine Photoproducts in Solar UV-irradiated Mammalian Cells" 275 : 26732-26742, 2000

26 Anne L, "Cycline D1 expression and cycle response in DNA mismatch repair-deficient cells upon methylation and UV-C damage" 292 : 123-134, 2004

27 Li H, "Colcemid inhibits the rejoining of the nucleotide excision repair of UVC induced DNA damages in Chinese hamster ovary cells" 488 : 188-128, 2005

28 Martin JA, "Chondrocyte senescence, joint loading and osteoarthritis" 427 : 96-103, 2004

29 Mikhailov A, "Cell cycle: Stressed out of mitosis" 12 : 331-333, 2002

30 Michele B, "Cell cycle regulation of the primitive dinoflagellate Crypthecodinium cohnii Biecheler: Evidence for the presence of a homolog of cyclin B" 84 : 35-42, 1995

31 Yamaji H, "Cell cycle analysis of Chinese hamster ovary cells stimulated by phosphatidic acid in serum-free culture" 98 : 487-489, 2004

32 Arivazhagan P, "Cardiolipin induces premature senescence in normal human fibroblasts" 323 : 739-742, 2004

33 Greenlee RT, "Cancer statistics" 50 : 7-33, 2000

34 Vreeswijk MP, "Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells" 269 : 31858-31863, 1994

35 Serrano M, "A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4" 366 : 704-707, 1993

36 Yang YT, "A cell cycle G0-ts mutant, tsJT60, becomes lethal at the nonpermissive temperature after transformation with adenovirus 12 E1B 19K mutant" 179 : 50-57, 1988

37 Dimri GP, "A biomarker that identifies senescent human cells in culture and in aging skin in vivo" 92 : 9363-6367, 1995