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      홍삼의 약리와 독성 기전에 대한 고찰

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      https://www.riss.kr/link?id=A99689071

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      참고문헌 (Reference)

      1 남기열, "홍삼과 백삼의 비교 고찰" 고려인삼학회 29 (29): 1-18, 2005

      2 박영철, "한약의 독물동태학적 특성" 대한예방한의학회 15 (15): 1-19, 2011

      3 홍희도, "증숙 횟수에 따른 고려인삼의 이화학적 특성 변화" 고려인삼학회 31 (31): 222-229, 2007

      4 박영철, "골개형(Bone Remodelling)의 분자생물학적 기전에 대한 노화,에스트로젠 및 산화적 스트레스의 영향" 한국독성학회 22 (22): 253-266, 2006

      5 Van MM, "l-ODAP alters mitochondrial Ca2+ handling as an early event in excitotoxicity" 47 : 287-296, 2010

      6 Lee JY, "Vascular Smooth Muscle Dysfunction and Remodeling Induced by Ginsenoside Rg3. a Bioactive Component of Ginseng" 117 (117): 505-514, 2010

      7 Gregoire FM, "Understanding adipocyte differentiation" 78 : 783-809, 1998

      8 Miyashita T, "Tumor suppressor p53 is a direct transcriptional activator of the human bax gene" 80 : 293-299, 1995

      9 Lin CL, "Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells" 2007

      10 Park YC, "The molecular & biochemical pronciples of toxiciology" Korean Studies Information LTD 2010

      1 남기열, "홍삼과 백삼의 비교 고찰" 고려인삼학회 29 (29): 1-18, 2005

      2 박영철, "한약의 독물동태학적 특성" 대한예방한의학회 15 (15): 1-19, 2011

      3 홍희도, "증숙 횟수에 따른 고려인삼의 이화학적 특성 변화" 고려인삼학회 31 (31): 222-229, 2007

      4 박영철, "골개형(Bone Remodelling)의 분자생물학적 기전에 대한 노화,에스트로젠 및 산화적 스트레스의 영향" 한국독성학회 22 (22): 253-266, 2006

      5 Van MM, "l-ODAP alters mitochondrial Ca2+ handling as an early event in excitotoxicity" 47 : 287-296, 2010

      6 Lee JY, "Vascular Smooth Muscle Dysfunction and Remodeling Induced by Ginsenoside Rg3. a Bioactive Component of Ginseng" 117 (117): 505-514, 2010

      7 Gregoire FM, "Understanding adipocyte differentiation" 78 : 783-809, 1998

      8 Miyashita T, "Tumor suppressor p53 is a direct transcriptional activator of the human bax gene" 80 : 293-299, 1995

      9 Lin CL, "Theaflavins attenuate hepatic lipid accumulation through activating AMPK in human HepG2 cells" 2007

      10 Park YC, "The molecular & biochemical pronciples of toxiciology" Korean Studies Information LTD 2010

      11 White TE, "The human estrogen receptor structural gene contains a DNA sequence that binds activated mouse and human Ah receptors: a possible mechanism of estrogen receptor regulation by 2,3,7,8-tetrachlorodibenzopdioxin" 193 : 956-962, 1993

      12 Yue YK, "The angiosuppressive effects of 20(R)- ginsenoside Rg3 Biochemical pharmacology" 72 : 437-445, 2006

      13 Fryer LG, "The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways" 277 : 25226-25232, 2002

      14 이남훈, "Systematic Review of Randomized Controlled Trials Evaluating the Efficacy and Safety of Ginseng" 세계약침학회 4 (4): 85-97, 2011

      15 Blomgren K, "Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia- ischemia: a mechanism of “"pathological apoptosis”"?" 276 : 10191-10198, 2001

      16 Sticher O., "Saponine in Pharmakognosie, Phytopharmazie" Springer Verlag 943-989, 2009

      17 Niu J, "Role of MCP-1 in cardiovascular disease: molecular mechanisms and clinical implications" 117 : 95-109, 2009

      18 Kim SY, "Repression of matrix metalloproteinase gene expression by ginsenoside Rh2 in human astroglioma cells" PERGAMON-ELSEVIER SCIENCE LTD 74 (74): 1642-1651, 2007

      19 Na L, "Protective effects of ginsenoside Rg2 against glutamate-induced neurotoxicity in PC12 cells" 111 : 458-463, 2007

      20 Liu M, "Protective effects of ginsenoside Rb1 and Rg1 on cultured hippocampal neurons" 674-678, 1995

      21 Zang M, "Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice" 55 : 2180-2191, 2006

      22 Zhang G, "Panax ginseng ginsenoside-Rg2 protects memory impairment via anti-apoptosis in a rat model with vascular dementia" 115 : 441-448, 2008

      23 Chen HS, "Open-channel block of N-methyl-d-aspartate(NMDA)responses by memantine : therapeutic advantage against NMDA receptor-mediated neurotoxicity" 12 : 4427-4436, 1992

      24 Park H, "Nitrogen Compounds of Korea Ginseng and Their Physiological Significance" 14 (14): 317-331, 1990

      25 Rudakewich M, "Neurotrophic and neuroprotective actions of ginsenosides Rb(1) and Rg(1)" 67 : 533-537, 2001

      26 Laurent M, "NOVH increases MMP3 expression and cell migration in glioblastoma cells via a PDGFR-alpha-dependent mechanism" 17 : 1919-1921, 2003

      27 Hugon J, "Magnetic cortical stimulation in patients with lathyrism" 88 : 412-416, 1993

      28 Sounni NE, "MT1-MMP expression promotes tumor growth and angiogenesis through an up-regulation of vascular endothelial growth factor expression" 16 : 555-564, 2002

      29 Morrison RS, "Loss of the p53 tumor suppressor gene protects neurons from kainate-induced cell death" 16 : 1337-1345, 1996

      30 Spencer PS, "Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA" 2 : 1066-1067, 1986

      31 Seely D, "Koren G. Safety and efficacy of panax ginseng during pregnancy and lactation" 15 : 87-94, 2008

      32 "Korean ginseng"

      33 Gervais FG, "Involvement of caspases in proteolytic cleavage of Alzheimer’'s amyloid-beta precursor protein and amyloidogenic A beta peptide formation" 97 : 395-406, 1999

      34 Foskett JK, "Inositol trisphosphate receptor Ca2+ release channels" 87 : 593-658, 2007

      35 Shinkai K, "Inhibitory of in vitro tumor cell invasion by ginsenoside Rg3" 87 : 357-362, 1996

      36 Mochizuki M, "Inhibitory effect of tumor metastasis in mice by saponins, ginsenoside- Rb2, 20 (R) – and 20 (R) –ginsenoside- Rg3, of Red ginseng" 18 : 1197-1202, 1995

      37 Fairweather D, "Inflammatory heart disease : a role for cytokines" 14 : 646-651, 2005

      38 Bocchino M, "Immunogenetics of severe respiratory infections: models for the development of new therapeutic strategies" 72 : 449-457, 2005

      39 Ericsson J, "Identification of glycerol- 3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory elementbinding protein-responsive gene" 272 : 7298-7305, 1997

      40 Ron FM, "Hormonal Signaling and Transcriptional Control of Adipocyte Differentiation" 3111-3121, 2000

      41 Van Damme P, "GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity" 88 : 1279-1287, 2002

      42 Kim YC, "Ginsenosides Rb1 and Rg3 protect cultured rat cortical cells from glutamate-induced neurodegeneration" 53 : 426-432, 1998

      43 Lee YJ, "Ginsenoside-Rg1, one of the major active molecules from Panax ginseng is a functional ligand of glucocorticoid receptor" 133 : 135-140, 1997

      44 Choi YJ, "Ginsenoside Rh1 inhibits the invasion and migration of THP-1 acute monocytic leukemia cells via inactivation of the MAPK signaling pathway" ELSEVIER SCIENCE BV 82 (82): 911-919, 2011

      45 김동현, "Ginsenoside Rg5 ameliorates lung inflammation in mice by inhibiting the binding of LPS to toll-like receptor-4 on macrophages" ELSEVIER SCIENCE BV 12 (12): 110-116, 201201

      46 Siegel RK, "Ginseng abuse syndrome" 241 : 15-23, 1979

      47 Herold S, "Exudate macrophages attenuate lung injury by the release of IL-1 receptor antagonist in Gram-negative pneumonia" 183 : 1380-1390, 2011

      48 MDidea, "Exporting Division Extracts Professional"

      49 Weisz A, "Estrogen stimulates transcription of c-jun protooncogene" 4 : 1041-1050, 1990

      50 Shi S, "Effects of steaming the root of Panax notoginseng on chemical composition and anticancer activities" 118 : 307-307, 2010

      51 Tao H, "Effect of angiogenesis inhibitor Rg3 on the growth and metastasis of gastric cancer in SCID mice" 40 : 606-608, 2002

      52 Ashida N, "Distinct signaling pathways for MCP-1-dependent integrin activation and chemotaxis" 276 : 16555-16560, 2001

      53 Lin CY, "Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells" 5 (5): 66-, 2004

      54 Kim SY, "Curcumin is a potent broad spectrum inhibitor of matrix metalloproteinase gene expression in human astroglioma cells" ACADEMIC PRESS INC ELSEVIER SCIENCE 337 : 510-516, 2005

      55 Johnson LN, "Cross-talk between pulmonary injury, oxidant stress, and gap junctional communication" 11 : 355-367, 2009

      56 Cheng LQ, "Conversion of major ginsenoside Rb1 to 20(S)-ginsenoside Rg3 by Microbacterium sp. GS514" 69 : 218-224, 2008

      57 Hashimoto K, "Components of Panax ginseng that improve accelerated small intestinal transit" 84 : 115-119, 2003

      58 Lee S, "Cholesterol-derived novel anti- apoptotic agents on the structural basis of ginsenoside Rk1, G.Q. Zhao, X.X. Wang" 17 : 34-43, 1986

      59 Oh JI, "Caspase-3-dependent protein kinase C delta activity is required for the progression of Ginsenoside-Rh2-induced apoptosis in SK-HEP-1 cells" ELSEVIER IRELAND LTD 230 : 228-238, 200512

      60 Yano K, "Bradykinin-induced rapid breakdown of phosphatidylinositol 4,5-bisphosphate in neuroblastoma X glioma hybrid NG108-15 cells" 259 : 10201-10207, 1984

      61 Lele RD, "Beyond reverse pharmacology: mechanism- based scereening of ayurvedic drugs" 1 (1): 257-265, 2010

      62 Kim YJ, "Antitumor activity of the ginsenoside Rk1 in human hepatocellular carcinoma cells through inhibition of telomerase activity and induction of apoptosis" 31 : 826-830, 2008

      63 Yun TK, "Anticarcinogenic effect of Panax ginseng C A. Meyer and identification of active compounds" 16 : 6-18, 2001

      64 Liu WK, "Anti-proliferative effect of ginseng saponins on human prostate cancer cell line" 67 : 1297-1306, 2000

      65 Hwang JT, "Anti-obesity effects of ginsenoside Rh2 are associated with the activation of AMPK signaling pathway in 3T3-L1 adipocyte" ELSEVIER 364 : 1002-1008, 2007

      66 Lee YJ, "A ginsenoside-Rh1, a component of ginseng saponin, activates estrogen receptor in human breast carcinoma MCF-7 cells" PERGAMON-ELSEVIER SCIENCE LTD 84 : 463-468, 2003

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2026 평가예정 재인증평가 신청대상 (재인증)
      2020-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2013-05-09 학회명변경 영문명 : Korean Oriental Medical Society -> The Society of Korean Medicine KCI등재
      2013-05-08 학술지명변경 외국어명 : The Journal of Korean Oriental Medicine -> Journal of Korean Medicine KCI등재
      2013-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2005-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2004-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2002-01-01 평가 등재후보학술지 유지 (등재후보1차) KCI등재후보
      2000-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.37 0.37 0.43
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.42 0.39 0.55 0.11
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