The impact of low forced vital capacity on behavior restrictions in chronic obstructive pulmonary disease patients = The impact of low forced vital capacity on behavior restrictions in chronic obstructive pulmonary disease patients

다국어 초록 (Multilingual Abstract)

Background: To evaluate the association between low FVC and behavior restrictions in COPD patients.
Methods: A cross-sectional study was performed using data from the Korean National Health and Nutrition Surveys conducted between 2007 and 2015. Participants aged 40 years to79 years with spirometry-defined COPD were analyzed to evaluate the association between low FVC (FVC＜80% predicted) and behavior restrictions.
Results: A total of 3,345 patients with COPD were included. The proportion of subjects with low FVC varied widely according to the severity of airflow limitations (0.8%, 36.1%, and 81.4% in the mild, moderate, and severe-to-very-severe COPD groups, respectively). As compared with moderate COPD subjects with normal FVC, those with low FVC were more likely to be older, never or ex-smokers; have larger waist size with higher body mass index, and have comorbidities such as diabetes, hypertension, dyslipidemia, and osteoporosis. Although there was no significant association between low FVC and behavior restrictions in the mild or severe-to-very-severe COPD groups, low FVC was independently associated with behavior restrictions in subjects with moderate COPD (adjusted odds ratio: 1.64, 95% confidence interval: 1.26-2.12).
Conclusion: In moderate COPD patients, low FVC was independently associated with behavior restrictions even after adjusting for confounding factors