Histographic analysis of magnetic resonance imaging for the evaluation of ovarian endometrial invasion = Histographic analysis of magnetic resonance imaging for the evaluation of ovarian endometrial invasion

다국어 초록 (Multilingual Abstract)

Objective: The purpose of the present study was to evaluate the usefulness of histographic analysis for the perfusion map of pelvic MRI in predicting remnant ovarian tissue in patients with ovarian endometriosis.
Methods: To generate the perfusion map, subtracted T1-WI was divided by contrast enhanced T1-WI with using image analysis software ImageJ. Each region of interest (ROI) was quantified by outlining of affected ovaries with endometrioma at the level with the largest area of normal ovary tissue and normal contralateral ovaries using the measurement tool on the software. Consequently, the number of ratios per each pixel composing perfusion map was scored from 0 (not perfused) to 1 (totally perfused). The pixel information, including area within ROI, mean with standard deviation of signal intensity, as well as integrated density of affected ovary with endometrioma, were compared with that of the normal ovary. In addition, we compared histogram according to severity of ovarian invasion.
Results: In comparison between affected ovary with endometrioma and normal ovary, perfusion ratio of normal ovary was higher than that of affected ovary (0.20 ± 0.12 versus 0.48 ± 0.07, p < 0.126), whereas area within ROI and perfusion ratio was higher in affected ovary. According to severity of endometrial invasion of ovary based on surgical findings, area with perfusion ratio between 0.4 and 0.8, (528.00 ± 154.43 versus 199.17 ± 163.15, p = 0.003), perfusion ratio (0.27 ± 0.11 versus 0.11 ± 0.07, p= 0.012), and, and integrated density (427.125 ± 132.24 versus 187.33 ± 106.32, p = 0.003) was lower in group of severe invasion than those of mild and moderate invasion group.
Conclusion: Histographic analysis for perfusion map of pelvic MRI could be useful in revealing the extent of the endometrial invasion and viable remnant ovarian tissue.