전이성 폐암으로 추정된 폐효모균증 = Pulmonary Cryptococcosis That Was Suspected to be Metastatic Lung Cancer

다국어 초록 (Multilingual Abstract)

Cryptococcosis is a subacute or chronic inflammation that’s caused by infection from cryptococcus neoformans in the soil or dust that’s contaminated by pigeon droppings. Pulmonary cryptococcosis occurs in immunocompromised patients, and particularly in HIV positive patients, but it rarely occurs in immunocompetent individuals. It is most often detected as asymptomatic single or multiple nodules that are found by chest X-ray examination. In these situations, the diagnosis for most cases is made by the histology of the resected lesion. We report here on a case of solitary nodular pulmonary cryptococcosis that occurred in a 32 years old female patient who underwent thyroidectomy for treating her thyroid cancer.

국문 초록 (Abstract)

효모균증은 비둘기의 배설물에 의해 오염된 먼지나 토양에 주로 존재하는 cryptococcus neoformans에 의한 아급성 또는 만성 감염이다. 폐의 효모균증은 건강한 사람에게는 잘 발생하지 않으며 면역이 저하된 환자 특히 후천성 면역결핍증 환자에게서 호발 한다. 일반적으로 증상이 없이 단순 흉부 X-선 검사에서 고립성 또는 다발성 폐 결절이 관찰되며, 이런 경우에는 대부분 절제된 조직의 병리학적 소견으로 진단된다. 본 증례는 갑상선 암으로 수술 받은 32세 여자환자에서 추적관찰 중에 발견된 좌하엽폐의 종괴가 전이성 폐암으로 추정되어 좌하엽폐 절제술을 시행한 후 폐 효모균증으로 확인되었다.

참고문헌 (Reference)

1 김병호, "폐 효모균증 -2예 보고-" 대한흉부외과학회 37 (37): 292-296, 2004

2 Dromer F, "Serotyping of cryptococcus neoformans by using a monoclonal antibody specific for capsular polysaccharide" 31 : 359-363, 1993

3 Dannaoui E, "Results obtained with various antifungal susceptibility testing methods do not predict early clinical outcome in patients with cryptococcosis" 50 : 2464-2470, 2006

4 Mitchell TG, "Cryptococcosis in the era of AIDS-100 years after the discovery of cryptococcus neoformans" 8 : 515-548, 1995

5 Mueller NJ, "Asymptomatic pulmonary cryptococcosis in solid organ transplantation: report of four cases and review of the literature" 5 : 140-143, 2003

6 안인선, "A Case of Pulmonary Cryptococcosis with Non-Small Cell Lung Cancer in Idiopathic CD4+ T-Lymphocytopenia" 연세대학교의과대학 46 (46): 173-176, 2005

7 Won Seok Cheon, "A Case of Pulmonary Cryptococcosis by Capsule-deficient Cryptococcus neoformans" 대한내과학회 21 (21): 83-87, 2006