혈액종양 : 암 환자에서 염산히드로모르폰 서방정의 효과와 내약성에 대한 연구

황준일 ( Jun Eul Hwang ),김대은 ( Dae Eun Kim ),김하나 ( Ha Na Kim ),윤주영 ( Ju Young Yoon ),배우균 ( Woo Kyun Bae ),심현정 ( Hyun Jeong Shim ),조상희 ( Sang Hee Cho ),정익주 ( Ik Joo Chung ) 대한내과학회 2011 대한내과학회지 Vol.80 No.3

Background/Aims: OROS hydromorphone is a synthetic opioid agent. While clinical studies have tested its effectiveness at controlling cancer-associated pain in patients who have received other strong opioids, no clinical studies have tested its effectiveness at managing cancer pain in strong opioid-naive patients. We performed the present study to evaluate the efficacy and tolerability of OROS hydromorphone in strong opioid-naive cancer patients. Methods: We administered OROS hydromorphone to patients who had not received strong opioids during the previous month. The starting dose was 8 mg/day. The dose was increased every 2 days in patients who experienced more than four episodes of breakthrough pain per day (more than four times in patients being treated with short-acting opioids). We evaluated the efficacy, safety and tolerability of ORS hydromorphone. We also evaluated patient satisfaction and investigators` global assessments. Results: We enrolled 23 patients to the study. The decrease in the numeric rating scale (NRS) was 59%. NRS variation had decreased markedly during the previous 24 h. All patients achieved stable pain control. The side effects were similar to those of other strong opioids. In total, 26% of patients were very satisfied with the treatment and 47% satisfied, and 74% of the investigators deemed OROS hydromorphone to be very effective or effective at controlling cancer pain. Conclusions: OROS hydromorphone is an osmotically driven, controlled-release preparation that is very effective and safe when administered once daily to strong opioid-naive cancer patients. (Korean J Med 2011;80:317-322)

괴사 근막염이 합병된 류마티스 관절염

황준일 ( Jun Eul Hwang ),우학 ( Hak Woo ),김상호 ( Sang Ho Kim ),이우석 ( Woo Seok Lee ),황재하 ( Jae Ha Hwang ),김정철 ( Jung Chul Kim ),조덕 ( Duck Cho ),박정진 ( Jeong Jin Park ),이신석 ( Shin Seok Lee ),박용욱 ( Yong Wook Pa 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.2

Necrotizing fasciitis is a life-threatening soft tissue infection involving skin, subcutaneous tissue, and superficial fascia. We report a case of necrotizing fasciitis that developed in a 76-year-old female patient taking low-dose methotrexate and prednisolone for rheumatoid arthritis (RA). A computed tomography scan of the neck during the initial work-up showed soft tissue swelling, loss of fat planes, and mild heterogeneous enhancement in the right lateral neck, suggesting cellulitis. The lesions were associated with skin necrosis and multiple bullae rapidly expanded to the right anterior chest in spite of empirical antibiotic therapy. Surgical debridement was immediately performed, and soft tissue biopsy from the lesions showed the pathologic finding consistent with necrotizing fasciitis. The skin wound defect was reconstructed by a flap operation with split-thickness skin graft. This case shows the development of necrotizing fasciitis in a elderly patient taking methotrexate and low-dose steroid for RA and highlights early recognition and prompt surgical debridement for successful management.

경영선수들의 상지 근력과 스트로크 변인이 수영 속도에 미치는 영향

황준일(Hwang, Jun-Il),어수주(Eo, Su-Ju),김효식(Kim, Hyo-Sik) 한국체육과학회 2012 한국체육과학회지 Vol.21 No.4

The purpose of this study was to determine the effects of stroke parameter and upper limb muscle power level by swim performance of competitive swimmers. Fourteen male college swimmers were performed swim trials and muscle power analysis. All swimmers were measured swim stoke parameters during maximal effort each swim stroke trails 50m and individual medley(IM) 200m. The result showed that 50m swim record was significantly different from IM 200m(p<.01). DPS(stroke per distance)(p<.01) and Lactate level(p<.05) were significantly difference between 50m and 200m swim. Moreover, there was more related to swim velocity in all swim trials (p<.05). Relationship of muscle power and swim performance were significantly difference between freestyle and butterfly. In conclusion, efficiency of swim stroke and muscle power were increased a beneficial effect on swim performance. Decrease in lactate concentration with swimming velocity may possibly contribute to improvement of swim performance for stroke efficiency, development of anaerobic capacity in elite swimmers.

A Design of Performance Management System in Heterogeneous Networks

황준,권혁인,Hwang, Jun,Kwon, Hyeog-In 한국정보처리학회 1995 정보처리논문지 Vol.2 No.2

분산된 정보 및 컴퓨터 자원들에 대한 접근 요구가 증대됨에 따라 네트워크 상호 연결도구 또한 커지고 있다. 네트워크 성능관리 도구들을 포함한 많은 네트워크 관리 패키지들이 이미 개발되었지만 이종 네트워크 환경에서는 그다지 적합하지 않다. 이종 네트워크의 성능을 효율적으로 감시하고 제어하기 위해서는 우선적으로 모든 성능 매개 변수를 정의해야 한다. 그리고 관리 시스템의 성능 분석 행위를 지원하기 위해서는 성능 분석 모델과 성능 판단 기준도 필요하다. 본 연구에서는 OSI 관리 체계 에 기반을 둔 이종 네트워크 환경에서 사용할 수 있는 중앙 집중식 성능 관리 시스템 을 설계하였다. As the needs for accessing distributed informations and computing resources are increasing the need for network interconnection is growing. There are many of the network management packages including performance management tools; but most of them are not appropriate to be used in heterogeneous interconnected networks. To monitor and to control efficiently the performance of heterogeneous network, first, we have to define all performance parameters in general meaning. We need models and criteria for supporting performance analysis activities of the management system. In this study, we have designed a centralized performance management system based on the OSI management, which can be used in heterogeneous networks.

국한 충돌공기제트에 의한 발포 알루미늄 방열기의 열전달 특성

황준,김서영,강병하,Hwang, Jun,Kim, Seo-Young,Kang, Byung-Ha 대한기계학회 2003 大韓機械學會論文集B Vol.27 No.4

An experimental study has been performed on thermal transport from an aluminum foam heat sink under a confined impinging air jet. Three kinds of aluminum foam heat sinks with 10, 20 and 40 PPI and a conventional pin-fin heat sink are tested in the present study. The jet Reynolds number is varied in the range of Re=667~5672 The effect of the confinement disk diameter and the distance between the confinement disk and the heater surface on the averaged Nusselt number is investigated in detail. The results are also compared with those of the unconfined impinging air jet. The critical distance, at which thermal performance shows a minimum compared to the unconfined jet impinging, will be described in terms of the Reynolds number and the pore density of the aluminum foam.

회원작품 - 용인 D 주택

황준,Hwang, Jun 대한건축사협회 2016 건축사 Vol.2016 No.3

증례 : 복합 항암화학요법으로 부분 관해를 이룬 전이성 갈색세포종 환자 1예

안재숙 ( Jae Sook Ahn ),심현정 ( Hyun Jeong Shim ),이세련 ( Se Ryeon Lee ),황준일 ( Jun Eul Hwang ),정성훈 ( Sung Hoon Chung ),김상호 ( Sang Ho Kim ),정익주 ( Ik Joo Chung ) 대한내과학회 2007 대한내과학회지 Vol.72 No.1S

증례 : 생식 세포종양으로 오인된 위의 간세포양 샘암종 1예

정성훈 ( Seong Hoon Jeong ),심현정 ( Hyun Jeong Shim ),황준일 ( Jun Eul Hwang ),김상호 ( Sang Ho Kim ),서성례 ( Seong Rye Seo ),임성욱 ( Seong Uk Lim ),정익주 ( Ik Joo Chung ) 대한내과학회 2007 대한내과학회지 Vol.73 No.1

저자들은 위암 2기(T2N1M0)로 근치적 수술을 시행 받은 후 추적 관찰 중 5개월 만에 높은 AFP수치(227,325 IU/mL)와 다수의 간 내 다발성 종괴 및 복강내 종양소견이 관찰되어 시행한 간 조직 검사와 면역조직화학염색을 통해 간세포양 샘암종으로 진단된 증례를 경험하였기에 보고하는 바이다. Hepatoid adenocarcinoma is a rare variant of adenocarcinoma that can occur in the stomach. This neoplasm has a poor prognosis and it frequently presents at an advanced stage of disease; it is clinically characterized by increased serum levels of alpha-fetoprotein (AFP) in most cases. We experienced a case of hepatoid adenocarcinoma of the stomach with multiple liver metastases that mimicked germ cell tumor in a 43-year-old man. He had incidentally detected gastric adenocarcinoma via gastrofibroscopy and he underwent subtotal gastrectomy. The postoperative pathologic stage was II (T2N1M0). He complained of epigastric pain. The serum AFP was markedly increased (227,325 IU/mL) and abdominal CT revealed multiple liver masses. We considered these as extragonadal germ cell tumors that occurred in the liver because of the markedly elevated AFP, the short duration of follow-up and early stage of stomach cancer at the that time. To confirm the diagnosis, biopsy of liver mass was done and he was diagnosed with hepatoid adenocarcinoma.(Korean J Med 73:107-111, 2007)

행성의 자기력을 이용한 캔위성의 자세제어

안병열(Ahn Byung Yeol),김상엽(Kim Sang Yeop),신동환(Shin Dong Hwan),황준서(Hwang Jun Seo),이철(Lee Chol) 한국항공우주학회 2018 한국항공우주학회 학술발표회 논문집 Vol.2018 No.11

제1형 신경섬유종증 환자에서 신경내분비종양과 위장관기질종양 2예

최원영 ( Won Young Choi ),홍승덕 ( Seung Dok Hong ),김하나 ( Ha Na Kim ),최유덕 ( Yoo Duk Choi ),황준일 ( Jun Eul Hwang ),심현정 ( Hyun Jeong Shim ),배우균 ( Woo Kyun Bae ) 대한내과학회 2011 대한내과학회지 Vol.81 No.6

Patients with neurofibromatosis type 1 (NF1) are at increased risk of developing tumors throughout the gastrointestinal tract, including neuromas, gastrointestinal stromal tumors (GISTs), and periampullary somatostatin-rich carcinoids. The simultaneous occurrence of a GIST and a well-differentiated neuroendocrine carcinoma in a patient with NF1 is very rare. Here, we report two cases of the coexistence of a low-risk GIST in the jejunum with a well-differentiated neuroendocrine carcinoma in the duodenum in patients with NF1. These cases strengthen the known association of GIST with neuroendocrine carcinoma in patients with NF1. (Korean J Med 2011;81:786-791)