학술연구논문 구두발표 2 : 인증림에서 생산된 펄프재의 가격차별화 방안

최상현,이재환,이유진,우종춘 한국임학회 2013 산림과학 공동학술발표논문집 Vol.2013 No.-

어체두부열수추출물에 관한 연구 2. 추출물의 기능특성

최상현,박성민,손병일,최현미,이근태,CHOI Sang-Hyeon,PARK Seong-Min,SON Byung-Yil,CHOI Hyeon-Mec,LEE Keun-Tai 한국수산과학회 1999 한국수산과학회지 Vol.32 No.5

The hydrothermal extracts were produced from fish head and their functional properties were investigated. The extracts exhibited an antioxidative effect and synergistic effect with $\alpha$-tocopherol by measuring peroxide values. The $5\%$ solution showed more antioxidative effect than $1\%$ solution. The extracts showed cryopropective effect, but the effect was less than sucrose. The solubility of the extracts was over $70\%$ in the all range of pH, and its lowest solubility was shown in pH 3.0. The extracts exhibited an emulsifying activity less than sugar ester (EAI=34.72) and little higher than or similiar to egg white (EAI= 14.69). The extracts showed a relatively high foam activity. The osmolality of the hydrothermal extracts at $1.0\%$ concentration were 23$\~$31 mOsmole which were much lower than 317 mOsmole at $1\%$ NaCl.

스너버에서의 마찰을 고려한 하부지지형 세탁기의 동특성 연구

최상현,김주호,한동철,한창소 한국소음진동공학회 1995 소음 진동 Vol.5 No.1

The vibration of the dehydration process in a washing machine is important problem that affects the performance of products. In this paper, the upper structure of a washing machine is modeled as rigid body suspension system and, by numerical analysis, the amplitude of a spin basket and the transfer moment at a base plate are calculated. To examine the vibrational characteristics according to design variable change, the friction coefficient in anubber, the radius of curvature, the stiffness coefficient, initial length and locations of support springs are considered in the analysis. Experimental results are compared with those of analysis.

어체두부열수추출물에 관한 연구 1. 추출물의 화학조성 및 물리적 특성

최상현,박성민,손병일,최현미,이근태,CHOI Sang-Hyeon,PARK Seong-Min,SON Byung-Yil,CHOI Hyeon-Mee,LEE Keun-Tai 한국수산과학회 1999 한국수산과학회지 Vol.32 No.5

Fish heads of the main by-product is fishery processing were treated to extract nutrients by heating the fish heads with 1.5 or 3.0 times added water during 9, 12 or 15 hours. The yield, chemical compositions and physical properties of the hydrothermal extracts were studied. The yield was increased with the amount of water added and the extracting hours. The extract contained about $80\%$ protein in solid basis, but has no lipid. In essential amino acid, glutamic acid was most abundant and Iysine was abundant. In free amino acid, $\delta$-hydroxylysine and L-histidine in Cypyrinus carpio linnaeus had 5 times more than those in Onchorhynchus keta, The solution of the extracts was known as Newtonian fluid and the color of the extracts showed lower whiteness, higher redness and higher yellowness.

실내기후실험실 단축 실험을 위한 해석 기법

최상현,배철호,정모,경남호,서항석,Choi, Sang-Hyun,Bai, Cheol-Ho,Chung, Mo,Kyong, Nam-Ho,Suh, Hang-Suk 대한설비공학회 2000 설비공학 논문집 Vol.12 No.4

Environmental chamber (EC) is an experimental facility used to analyze the characteristics of thermal response of testing objects by the artificial control of weather conditions. The EC in KIER can simulate the weather conditions by the control of temperature, humidity, and solar radiation. A two-storied testing building is located inside of EC. For the exact thermal response analysis of testing building, monthly or yearly scheduled operations are necessary. Although this long term operation gives the exact experimental data, it requires a high operational cost, long duration, and lots of manpower. Therefore it is necessary to perform the shortened experiments without sacrificing the validity of the obtained results. Since the characteristics of thermal response from the shortened experiments are different from the full time results, the analytical method to analyze the thermal response from the shortened experiments to estimate a full times results is developed in this study. The thermal response of testing building is performed using commercial software TRNSYS.

유비쿼터스 네트워크와 비이오 기술

최상현 한국통신학회 2005 정보와 통신 Vol.22 No.7

다양한 형태의 데이터 입력을 지원하는 AHP 시스템 개발 및 전략적 의사 결정에의 응용

최상현,김진욱,한관희 대한산업공학회 2011 산업공학 Vol.24 No.3

The traditional AHP(Analytic Hierarchy Process) is to evaluate subjectively the alternatives in the view point of each of criteria and has been widely used at the fields of real world application. The AHP has some drawbacks that makes it difficult to keep the consistency of decision makers' input and take too long to get accurate results because of requiring lots of pairwise comparison between criteria and alternatives. This research is to propose and develop a Hybrid-AHP system for complementing the critical points of traditional AHP methodologies. This system gets the quantitative information as well as qualitative inputs as the comparative ones between criteria and alternatives. We use the input as various type of information such as quantitative values, 9-scale ratings, and fuzzy-based inputs. Finally, we applied the system to the case of choosing strategic industries. The case study have shown the use of various input methods saves processing time, and reduces the input burden of users.

Inhibitory Effects of Amitriptyline, Sertraline and Chlorpromazine on the Thrombin-induced Aggregation of Platelets

최상현,이영재,신경호,천연숙,전보권,Choi, Sang-Hyun,Lee, Young-Jae,Shin, Kyung-Ho,Chun, Yeon-Sook,Chun, Boe-Gwun The Korean Society of Pharmacology 1995 대한약리학잡지 Vol.31 No.3

Platelets resemble monoaminergic neurons in several respects, i.e. the uptake of 5-HT and its inhibition, the subcellular storage and release of 5-HT, and the metabolism of aromatic amines brought about by monoamine oxidase. And the 5-HT content of rabbit platelets is well known to be about 40 times higher than that of human platelets. Therefore, this study was carried out to investigate the influences of amitriptyline (AMT) and sertraline (SRT) on the aggregation, contents of signaling second messengers, and protein phosphorylations of rabbit platelets in response to thrombin, 0.25 unit/ml, comparing with those of chlorpromazine (CPZ). Thrombin-induced aggregation was inhibited by SRT $(IC50:4.37{\times}10^{-5}\;M)$, CPZ $(IC50:5.76{\times}10^{-5}\;M)$, and AMT $(IC50:1.15{\times}10^{-4}\;M)$, respectively, and the aggregation by A23187 $(1.0\;{\mu}M)$ or PMA (320 nM) was also inhibited by SRT, CPZ, and AMT. AMT, SRT, and CPZ had little affects on basal contents of platelet $TXB_2$ and $PGE_2$, but all of them inhibited the thrombin-induced increase of $TXB_2$. Thrombin did not change the platelet contents of cAMP and cGMP. CPZ, AMT, and SRT produced the slight decrease of basal cAMP content, and their effects were not affected by thrombin-treatment. But SRT and AMT moderately increased the basal cGMP content, and the cGMP content of thrombin-stimulated platelets was gradually increased by the pretreatment with SRT, AMT, and CPZ. Particularly, the SRT-dependent increase of the cGMP content was notable. Platelet $Ins(1,4,5)P_3$ content was rapidly increased up to a plateau within 10 sec after thrombin-stimulation, AMT, SRT, and CPZ increased the basal $Ins(1,4,5)P_3$ content, and the thrombin-dependent increase was enhanced by pretreatment with CPZ and AMT, but was blunted by SRT. Platelet $[Ca^{2+}]_i$, was rapidly increased up to a peak level within 20 sec after thrombin-stimulation. The increase of $[Ca^{2+}]_i$ was sisnificantly inhibited by AMT, SRT, and CPZ. Thrombin- or PMA-induced phosphorylations of platelet $41{\sim}43\;kDa$ and 20 kDa proteins were significantly inhibited by AMT, SRT, and CPZ. These results suggest that the antiplatelet activities of AMT and CPZ may be considerably attributed to the inhibition of protein kinase C activity, and the activity of SRT may be associated with the inhibitory effect on the thrombin-induced increase of $Ins(1,4,5)P_3$ and the increasing effect on the cGMP content of ptatelets. Therefore, it seems to be evident that AMT and SRT may produce their antidepressant activity, at least, partly through the inhibition of protein kinase C activity or the increase of resting $Ins(1,4,5)P_3$, content and in case of SRT, to a lesser extent, via the increase of cGMP in the brain.

Influences of Hydrocortisone, DHEA, Estradiol and Testosterone on the Hepatic and Intestinal Polyamine Metabolism of Castrated Mice

최상현,전보권,김남헌,천연숙,Choi, Sang-Hyun,Chun, Boe-Gwun,Kim, Nam-Hun,Chun, Yeon-Sook The Korean Society of Pharmacology 1990 대한약리학잡지 Vol.26 No.1

웅성-마우스의 고환을 diethyl ether 마취하에서 제거하고, 수종의 steroid 홀몬을 각각 매일 1회씩 4일간 피하주사하여, 간 및 소장의 polyamine 함량과 소장의 diamine oxidase (DAO) 활성도에 미치는 그들의 영향을 검색하였다. 1. Hydrocortisone succinate 50 mg/kg (HC) 및 dehydroepiandrosterone 250 mg/kg (DHEA)에 의하여, 소장의 putrescine (PT)은 유의하게 증가되었으나, spermidine (SD) 및 spermine (SM)은 별 영향을 받지 않았고, 간의 SD은 다소 증가되고, SM은 다소 감소 되었으나, PT은 별 변동을 보이지 않았다. 2. Estradiol cypionate 5 mg/kg (E2)에 의하여, 간의 PT은 현저히 증가되었으나, 소장의 PT은 다소 증가되었고, 그외 소장 및 간의 SD와 SM의 변동은 보이지 않았다. Testosterone cypionate 5 mg/kg (TS)에 의하여는 간의 SD이 다소 감소되었을 뿐 별 변동이 없었다. 3. 소장의 DAO 활성도는 HC에 의하여 현저히 감소되었으나, E2 및 TS에 의하여는 유의하게 증가되었고, DHEA에 의하여는 별 영향을 받지않았다. 그러나 간의 monoamine oxidase 활성도는 HC, E2, DHEA, 및 TS에 의하여 영향을 받지 않았다. 4. Aminoguanidine 25 mg/kg로 소장의 DAO 활성도가 현저히 감소되었으나, 간 MAO 활성도는 영향을 받지 않았고, 소장의 PT 및 SD은 유의하게 증가되었으나, 간의 polyamine은 별 변동을 보이지 않았다. 이상의 결과로 미루어 볼때, 간 및 소장의 polyamine 대사-특히 PT 함량의 변동이 각각 E2 및 HC에 의하여 특이적으로 조절되는 바, E2에 의한 간 PT 함량의 증가는 주로 생성촉진 작용에 연유되며, HC에 의한 소장 PT 함량의 증가는 주로 polyamine의 이화성 대사를 억제함에 기인될 수 있는 것으로 사료된다. Hydrocortisone 50 mg/kg (HC), dehydroepiandrosterone 250 mg/kg (DHEA), ${\beta}-estradiol$ 5 mg/kg (E2), and testosterone 20 mg/kg (TS) were subcutaneously injected into the castrated ICR mice at noon for four days, and the animals were sacrificed at 10-12 A.M. of the fifth day. The intestinal DAO activity was significantly decreased by HC, but it was rather increased by E2 and TS, respectively. And DHEA did not change the DAO activity. But the hepatic MAO activity was not affected by anyone of HC, DHEA, E2, and TS. Aminoguanidine 25 mg/kg produced the marked decrease of the intestinal DAO activity and the significant increases of the intestinal PT and SD contents, but it did not change the hepatic polyamine contents. HC and DHEA induced the significant increase of the intestinal PT content. E2 induced the marked increase of the hepatic PT content and the moderate increase of the intestinal PT content. TS little affected the polyamine contents of the liver and intestine. These results suggest that the E2-induced increase of the hepatic PT content is rather ascribed to the greater enhancement of PT synthesis than the inhibition of polyamine catabolism, and that the HC-induced increase of the intestinal PT content is due partly to the inhibition of polyamine catabolism via DAO.

선진국의 소프트웨어 개발동향

최상현,Choe, Sang-Hyeon 한국전자정보통신산업진흥회 1990 電子振興 Vol.10 No.3