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조재화,남문석,이은직,오세창,김경래,임승길,이현철,허갑범,이상인,이관우 한국지질학회 1994 韓國脂質學會誌 Vol.4 No.2
The purpose of this study was to examine the level of serum total cholesterol and triglyceride of healthy Korean adults and the correlation between these serum lipid levels and other metabolic or anthropometric parameters. Measurement of percent ideal body weight(PIBW), body mass index (BMI), blood pressure, serum total cholesterol, triglyceride, blood glucose and hepatic and renal fuctional test were made to each of 8,208 healthy adults; 4,380 males and 3828 females. The mean serum total cholesterol and triglyceride were 185.2±36.0㎎/㎗ and 112.9±64.4㎎/㎗ respectively. Serum total cholesterol and triglyceride showed a gradual increase with age in both sex upto sixth decade. The percent increases in serum cholesterol and triglyceride levels of females after sixth decade were much greater than those of male. The serum total cholesterol showed a normal distribution curve but the serum triglyceride showed a skewed curve. The serum total cholesterol levels had positive correlation with age, PIBW, BMI and blood pressure. The serum triglyceride had positive correlation with PIBW, BMI, age and blood pressure.
조재화,김태희,남현승,최은영,장유진,최원일,황재준,문재영,이광하,김세원,강형구,심윤수,박태선,박승용,박성훈,( Korean Niv Study Group ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Introduction: The use of sedative drugs may be an important therapeutic intervention in patients with high risks such as mask intolerance, delirium, and agitation. However, there is little data on sedation during NIV maintenance. The Korean noninvasive mechanical ventilation study group has prospectively collected NIV use data from ICUs. Objectives: We analyzed status and safety in the management of pain, sedation on NIV therapy in Korean ICU. Methods: The twenty ICUs intensivists among Korean nationwide hospitals were participated and collected data of NIV from June 2017 to April 2018. We analyzed using chi-square test and Fisher’s exact test on categorical variables and Mann-Whitney U test on continuous variables. Results: The 155 patients were included during those periods. We divided the intervention group (n=26) that who received management of sedation and control group (n=129). The PaCO2 and PF ratio before NIV and 30 minutes after NIV were not different between intervention and control group. There was no statistically significant difference in success rate of NIV weaning, complications, length of ICU stay, ICU and hospital survival rate. However, duration of NIV apply were shorter in intervention than in control (1.5 days versus 4 days, p=0.001). Conclusion: In the NIV patients, pain and sedation therapy might have no harmful effect on complications, NIV weaning success, and mortality compared to the control group. Pain and sedation might have reduced the duration of NIV. Thus control of pain, sedation during NIV might be safe with close monitoring.
A Pulmonary Nodule due to Pulmonary Infarction Diagnosed by Video-Assisted Thoracoscopy
조재화,김루시아,이경희,곽승민,이홍렬,김정택,류정선 연세대학교의과대학 2009 Yonsei medical journal Vol.50 No.4
We report a pulmonary infarction in 68-year-old man who was referred for an asymptomatic pulmonary nodule in chest radiography. Computed tomography (CT), positron emission tomography (PET), and transthoracic needle aspiration suggested suspicion for malignancy. Video-assisted thoracoscopic surgery (VATS) was performed for histologic diagnosis. Our case is a pulmonary nodule due to pulmonary infarction diagnosed by VATS in Korea. We report a pulmonary infarction in 68-year-old man who was referred for an asymptomatic pulmonary nodule in chest radiography. Computed tomography (CT), positron emission tomography (PET), and transthoracic needle aspiration suggested suspicion for malignancy. Video-assisted thoracoscopic surgery (VATS) was performed for histologic diagnosis. Our case is a pulmonary nodule due to pulmonary infarction diagnosed by VATS in Korea.
중환자실 구성이 2009년 인플루엔자 A/H1N1 중증환자의 사망률에 미친 영향
조재화,이훈재,홍상범,서지영,박무석,김석찬,곽상현,이명구,임재민,이현경,고윤석,대한중환자학회h1n1연구회 대한중환자의학회 2012 Acute and Critical Care Vol.27 No.2
Background: During 2009 pandemic period, many Koreans were infected and admitted with Influenza A/H1N1. The primary aim of this study was to evaluate whether the structures of an intensive care unit (ICU) were associated with the outcomes of critically ill patients. Methods: This retrospective observational study examined critically ill adult patients with influenza A/H1N1, who were admitted to 24 hospitals in Korea, from September 2009 to February 2010. We collected data of ICU structure, patients and 90 days mortality. Univariate and multivariate logistic regression analysis, with backward elimination, were performed to determine the most significant risk factors. Results: Of the 239 patients, mortality of 90 days was 43%. Acute physiology and chronic health evaluation (APACHE) II score (p < 0.001), sequential organ failure assessment (SOFA) score (p < 0.0001), nurse to beds ratio (p = 0.039) and presence of intensivist (p = 0.024) were significant risk factors of 90 days mortality. Age (p = 0.123), gender (p = 0.304), hospital size (p = 0.260), and ICU type (p = 0.409) were insignificantly associated with mortality. In a multivariate logistic regression analysis, patients with less than 6 SOFA score had significantly lower mortality, compared with those with more than 10 SOFA score (odds ratio 0.156, p < 0.0001). The presence of intensivist had significantly lower mortality, compared with the absence (odds ratio 0.496, p = 0.026). Conclusions: In critically ill patients with influenza A/H1N1, the severity of the illness and presence of intensivist might be associated with 90 days mortality.