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- 저자 : 정호연(Ho Yeon Chung) (검색결과 55 건)
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정량적 초음파 측정기 QUS-2로 종골에서 측정한 한국 여성의 BUA
정호연(Ho Yeon Chung),한인권(In Kwon Han),윤현구(Hyun Koo Yoon),오한진(Han Jin Oh),김종한(Jong Han Kim) 대한폐경학회 1999 대한폐경학회지 Vol.5 No.1
Background: Quantitative ultrasound is a newly developed radiation free technique that measures bone properties and may assess bone quality. Some of these devices are wet, i.e., require a water bath, while the others are dry requiring only gel to facilitate coupling the skin and transducer. But these devices known that had some pmblems in reproducibility of its data. Recently, QUS-2 (Metra Biosystems Inc., USA) as a dry scanning quantitative ultrasound system has been newly developed with unique mechanism to identify the back and bottom edges of the heel bone to allow consistent localization of the region of interest (ROI) in an individual. So we have assessed a newly developed QUS-2 for measuring broadband ultrasound attenuation (BUA) at calcaneus in Korean Women. Subjects and Methods: We measured BUA at calcaneus in 423 Korean women aged 17-72, Among them 200 women were measured BMD at lumbar spine, and 107 women were also measured BMD of femur neck, trochanter and wards triangle with XR-36 (Norland, USA), Subjects were measured height, weight, and foot length. BUA analyzed according to their age and BML Also, we evaluate correlation with BUA and BMD measured by DEXA machine. Results: Peak BUA is 90.7+-17.0dB/MHz in 30-34 age group. BUA in Korean women decreased slowly with age after that age group. Rapid reductions of BUA were noticed in 6th and 7th decade. BUA was significantly associated with age, but not with BML T-score were made with BUA of 151 women aged 25 to 34. Using the T-score, subjects wae classified with 3 groups. So, 133 women (31.4%) were classified as osteopenia and 12 women (2.8%) as osteoporosis by WHO criteria for osteoporosis. BUA correlated well with BMD of the spine, femur neck, trochanter and wards triangle. The correlation coefficients of the spine, femur neck, trochanter and wards tirangle with BUA were 0.521, 0,517, 0.534, and 0.562. Conclusions: BUA in Korean women peaks at 30-34 age group. BUA was associated with age. The pattern of decline in BUA by age was similar with BMD measured by DEXA system. BUA also correlated well with the BMD of various sites, So we conclude that QUS-2 has potential for the use in the evaluation of bone strength.
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정호연(Ho Yeon Chung),임창훈(Chang Hoon Lim),김상우(Sang Woo Kim),한기옥(Ki Ok Han),한인권(In Kwon Han),민헌기(Hun Ki Min),조진아(Jin A Cho),윤현구(Hyun Koo Yoon),홍성란(Sung Ran Hong) 대한폐경학회 1997 대한폐경학회지 Vol.3 No.1
Menopause refers to the complete or permanent cessation of menstruation. One the other hand, climacteric refers to the phase of the aging process of women, which a transition is made from the reproductive stage of life to the nonreproductive stage. Due to decreasing the estrogen in the menopause, many postmenopausal discomforts are appeared. Estrogens for hormone replacement therapy is important for a variety of functions including recreation of the receptive endometrial environment and symptomatic relief of hot flushes, genitourinary symptoms, osteoporosis prophylaxis, psychological well-being, and reduction of coronary heart disease. Elevated serum estradiol level varies by composition of the prescribed estrogens, after hormone replacement therapy gonadotropin level decreases and ovulation induction is achieved. Recently we experienced a case of pregnancy with hormone replacement therpay in menopausal woman, so we report the case with a review of literature.
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폐경 후 여성에서 생화학적 지표의 비교 분석에 관한 연구
정호연(Ho Yeon Chung),임창훈(Chang Hoon Lim),김상우(Sang Woo Kim),한기옥(Ki Ok Han),한인권(In Kwon Han),민헌기(Hun Ki Min) 대한폐경학회 1996 대한폐경학회지 Vol.2 No.2
To evaluate the clinical utility of recently devdoped biochemical markers in postmenopausal women, we compared the results of six assay for markers of bone formation, such as bone specific alkaline phopohatase & serum osteocalcin measured by RIA, ELISA(Novocalcin & N-mid terminal) and resorption, such as urinary deoxypyridinoline(Pyrilinks-D) and urinary degradation product of type I collagen peptides(CrossLaps). The intraassay coefficients of variation were less than 8% except Novocalcin(13.3%) and N-mid terminal osteocalcin(15%). Highly significant correlations were observed between tumover markers(r=0.625-0.953, p<0.001) except N-mid terminal osteocalcin. Before we analyze correlation between BMD and tumover markers, we have to standardize patient's BMD values among different dual X-ray aborptiometry(DEXA) scanners from three manufacturers. European spine phantom & patient for standardization for DEXA were evaluated on three system(DPX-L, XR36, QDR2000) and the linear regression equations calculated Overall correlation between instruments were highly significant using phantom(r2=0.995-0.998) and patients(r2=0.973-0.978). In simple regression analysis, corrected spinal BMD using regression equation was significantly correlated with Novocalcin(r=0.38, p=0.01) and osteocalcin by RIA(r=0.4, P=0.01). But stepwise regression showed that YSM(years since menopause), Pyrilinks-D and N-mid terminal osteocalcin use of currently available biochemical markers of bone tumover shows that they nearly all have a role to play in diagnostic procedure. Combination of two to three markers determined at baseline in postmenopause women might predict bone loss.
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정호연(Ho Yeon Chung),이석훈(Suk Hoon Lee),김병호(Byung Ho Kim),이정일(Joung Il Lee),장영운(Young Woon Chang),장린(Rin Chang) 대한내과학회 1989 대한내과학회지 Vol.37 No.4
N/A In order to assess the sensitivity and positive predictive value of ultrasonographic diagnosis of clonor- chiasis, we performed a retrospective analysis of 73 patients who were examined by ultrasonography and stool examination (EPD; Egg per day) and diagnosed as having clonorchiasis by one or both of the above examinations from Jan. 1985 thru Mar. 1987. Forty patients showed positive findings on ultrasonography and stool examination, 26 patients only on stool examination and 7 patients only on ultrasonography. When we acknowledged eggs in the stool as a confirmative diagnosis of clonorchiasis, the sensitivity of ultrasonography was 60.6% and the positive predictive value was 85.1% Thus, abdominal ultrasonography is thought to be a highly reliable method of diagnosis of clonorchiasis, but is inadequate as a screening method for the detection of patients with clonorchiasis.
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폐경후 여성에서 경피적 에스트라디올 겔과 경구영 프로게스테론 주기적 병합요법의 임상적 유효성에 관한 연구
정호연 ( Ho Yeon Chung ),최규홍 ( Kyu Hong Choi ),이창욱 ( Chang Uk Lee ),김해성 ( Hae Sung Kim ),임창훈 ( Chang Hoon Yim ),한기옥 ( Ki Ok Han ),장학철 ( Hak Chul Jang ),윤현구 ( Hyun Koo Yoon ),한인권 ( In Kwon Han ) 대한폐경학회 2001 대한폐경학회지 Vol.7 No.1
Objectives: The purpose of our study was to evaluate the effects of transdermal 17β -estradiol gel combined with oral progestogen in terms of serum lipid, bone markers and bone mineral density in Korean postmenopausal women Subjects and methods: Nine healthy postmenopausal women were asked to volunteer for pharmacokinetic analysis of estradiol gel. Subjects received daily application of 1.5 ㎎ of estrogen gel in the morning. Peripheral venous samples were drawn at 0, 0.5, 1, 2, 4, 8, 24, 48, 72 hours after the daily gel application and serum E2 levels were analyzed. 41 postmenopausal women with intact uterus and no menstruation for more than 12 months were treated with 1.5 ㎎ of estradiol gel (day 1-25) sequentially combined with 2.5㎎ of medroxyprogesterone acetate (day 16-25) orally for 1 year. Results: Although one volunteer showed increment of serum E2 one hour after application of estrogen gel, pharmacokinetic study showed increase of serum E2 after 24 hours in the most volunteers. The mean serum E2 level at 72 hour after application was 59.6±58.8 pg/㎖. The acceptability of the combined treatment was 73.2%. Only 1 (3.3%) woman complained skin irritation during treatment. The combined estradiol gel and oral progestogen therapy significantly decreased serum cholesterol levels by 7.8%, LDL by 8.5%. Markers of bone turnover significantly decreased 3 months after treatment. The increase of the annual percent change in bone density was 4.8% at the lumbar spine and 4.4% at the femoral neck. Conclusion: The combined estradiol gel with oral progestogen therapy is acceptable and effective treatment in postmenopausal women.
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부패성 아스페르길루스증을 동반한 제 1형 선천성 폐기도 기형 1예
김정욱 ( Jung Wook Kim ),정호연 ( Ho Yeon Chung ),김은영 ( Eun Young Kim ),김현수 ( Hyun Soo Kim ),강경환 ( Kyung Hwan Kang ),박지영 ( Ji Young Park ),이은정 ( Eun Jung Lee ),위정국 ( Jung Kook Wi ),조경민 ( Kyoung Min Cho ),정회 전북대학교 의과학연구소 2011 全北醫大論文集 Vol.35 No.1
Congenital pulmonary airway malformation (CPAM) of the lung, also known as congenital cystic adenomatoid malformation, is an uncommon fetal developmental anomaly and presentation in adult is very rare. We experienced an unusual manifestation of CPAM with colonization of Aspergillus organisms in a 57-year-old male. Only one case of CPAM with aspergilloma has been reported to date.
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박기철(Ki-Chul Park),정호연(Ho-Yeon Chung) 한국산학기술학회 2021 한국산학기술학회논문지 Vol.22 No.12
TPM(Total Productive Management)에 관한 대부분 선행연구들은 중소기업을 위주로 연구하였고, 기업의 주관적 의견이 많이 반영되는 설문조사에 의한 연구들로, TPM 성과의 검정면에서 대표성과 객관성이 다소 결여 되었다. 따라서, 본 연구에서는 최근 7개년(2014-2020)간 한국표준협회(KSA) 「전국 품질분임조 경진대회 설비(TPM)부문」에 입상한 총 83개 우수기업의 객관적인 실증데이터를 활용하여 연구결과에 대한 신뢰성 높였으며, 다수의 대기업과 중견 기업을 포함한 산업 전반에 대한 대표성 있는 연구로써 선행연구들과 차별성이 있다. 본 연구에서는 분임조 활동의 주요인자(개별개선 건수, 활동기간, 근속년수)와 TPM의 주요 성과(시간가동률, 성능가동률, 설비종합효율)간 유의적인 인과관계를 분석하였으며 다음과 같은 연구결과를 도출하였다. 첫째, 개별개선 건수는 시간가동률(β=.362, p<.001), 설비종합효율(β=.415, p<.001)에 긍정적인 영향력을 미쳤다. 둘째, 활동기간은 시간가동률(β=.328, p<.01), 성능가동률(β=.346, p<.01), 설비종합효율(β=.430, p<.001) 모두에게서 긍정적인 영향력을 미쳤다. 셋째, 근속년수는 시간가동률(β=-.364, p<.01), 성능가동률(β=-.350, p<.01), 설비종합효율(β=-.339, p<.01)에 있어서 부(-)의 영향력을 미치는 것으로 해석되었다. 이는 작업자의 능력이 첨단화되는 설비 발달 속도를 따라가지 못하고, 업무능력을 키우는 데는 시간이 필요하다는 관점과 분임조 구성원의 높은 근속년수는 설비운영 및 현장관리에 있어 기존 관성에 익숙한 반복적 활동이 지속될 가능성을 내포하고 있다. 이러한 연구결과를 바탕으로, 유의적인 분임조 활동요인의 역량강화에 집중하며 TPM 활동성과에 기여 할 수 있는 강력한 도구(Tool)로써 활용하고자 한다. Most of the previous studies on total productive management (TPM) focused on small and mid-size enterprises (SMEs) and were based on surveys that eventually reflected a lot of subjective opinions of companies. This study used objective empirical data of a total of 83 outstanding companies that won the Korea Standards Association (KSA) National Quality Division over the past 7 years, increasing the reliability of their research results. A significant relationship between the main factors of divisional group activities (number of individual improvements, duration of activities and years of service) and the performance of TPM (time operation rate, performance operation rate and facility comprehensive efficiency) was analyzed. The number of individual improvements had a positive effect on the time operation rate and facility comprehensive efficiency. The activity period had a positive effect on the time operating rate, the performance operation rate and facility comprehensive efficiency. The number of years of service had a negative influence on the performance operation rate and facility comprehensive efficiency.
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Clear Cell Chondrosarcoma of the Tibia Diaphysis: A Case Report
강창민,한정수,정광영,정호연,김영준,Kang, Chang Min,Han, Chung Soo,Jung, Gwang Young,Jeong, Ho Yeon,Kim, Young Jun The Korean Musculoskeletal Tumor Society 2014 대한골관절종양학회지 Vol.20 No.2
Clear cell chondrosarcoma is a very rare malignant bone tumor that shows a strong predilection for the epiphysis or metaphysis of long bones. Many studies have reported that the proximal end of the femur is the most commonly affected site, followed by the proximal end of the humerus. Histopathologically, tumor cells of this type have centrally located round nucleoli with clear cytoplasm and a distinct cytoplasmic membrane. Generally, clear cell chondrosarcomas is not confused with conventional chondrosarcomas. However, when it involves the diaphysis in long bones, diagnosis can be hindered, as only three reports of this exist in the literature. We report herein an unusual case of clear cell chondrosarcoma of the tibial diaphysis in a 42-year-old male.
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