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Se Hwan JUNG(정세환),Ju Hyeon PARK(박주현),Sung Hwan PARK(박성환),Sang Jung AHN(안상중),Na Young KIM(김나영),Jun Young CHAE(채준영),Moo-Sang KIM(김무상),Joon Ki CHUNG(정준기),Hyung Ho LEE(이형호) 한국수산해양교육학회 2025 수산해양교육연구 Vol.37 No.4
Phospholipase D (PLD) is an important enzyme that plays a pivotal role in the phospholipid metabolism and signaling, including membrane trafficking, cytoskeletal reorganization, receptor-mediated endocytosis, exocytosis, and cell migrationin. In this study, we identified an additional PLD1 gene in the olive flounder (Paralichthys olivaceus), which emerged through fish-specific genome duplication (FSGD), and designated it as PoPLD1B. Notably, the expression pattern of PoPLD1B differs significantly from that of both PoPLD1A and mammalian PLD1 isoforms. PoPLD1B exhibits high expression in digestive organs, including the gullet, pyloric ceca, stomach, and intestine. Furthermore, recombinant PoPLD1B protein, overexpressed using the pCold TF vector, demonstrated phosphatidylcholine (PC)-hydrolyzing activity in the presence of ADP-ribosylation factor 1 (ARF1). Collectively, these findings indicate that ARF1-dependent activation of fish PLD1B plays a crucial role in digestive organs and gill function, particularly in osmotic and ionic regulation, acid-base balance, nitrogenous waste excretion, and calcium ion homeostasis.
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한국의료패널의 치과외래 이용 및 의료비 지출에 대한 4년간(2008-2011)의 변화추이
정세환(Se-Hwan Jung) 대한치과의사협회 2014 대한치과의사협회지 Vol.52 No.5
Korea Health Panel Survey (KHPS) has been conducted to provide nationally representative estimates of health care use and expenditures for non-institutionalized population in Korea since 2008. The aim of this study was to present estimates from KHPS on dental utilization and expenditures from 2008 to 2011. While weighted estimates were presented for each year from 2008 to 2011, the focus of this study was on the 2011 estimates and changes in dental utilization and expenditures between 2008 and 2011. Weighted estimates were obtained using population weights and statistical significances were analysed by independent t-test or ANOVA test using SPSS version 20 for Windows. In 2011, 21.1% of Korean population obtained outpatient dental services from dentists. From 2008 to 2011, the percent of people with a dental visit in each year increased slightly. In 2011, the mean number of dental visits was 4.46. While the mean number of dental visits remained stable by 2010, it increased slightly in 2011. The total annual dental expense in 2011 for people with a visit was about 460,000 Korean Won and 10% higher in 2008. In summary, this study results highlight low rates of dental utilization and high dental expenses in Korean population.
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