구내 하악골 상행지 역L형 골절단술에 의한 하악골 전돌증의 치험례

장현중 慶北大學校 齒科大學 1991 慶北齒大論文集 Vol.8 No.1

We have met a 21-year-old woman with mandibular prognathism and excessive long face. At first, she had been visited to department of orthodontics for malocclusion & esthetic problems. She received prosurgical orthodontic for 1 year. Therefter, she was admitted to our department because of facial esthetic problem in the course of orthodontic treatment. We have obtained good results by surgical approach as follows. 1. Mandibular prognathism that required 15㎜ or more of correction is corrected by reverse L-osteotomy postoperative results were good both functionally & esthetically. 2. Pedicle of medial pterygoid muscle remains atached to posterior & Medial aspect of the proximal segment. This procedure eliminates the need for wiring proximal segment and normal muscular tone will “seat”and maintain the condyle in the fossae. J. Kyungpook Nat. Univ. Sch. Dent. Vol.8, No.1,19∼25, 1991.

측사위경두개방사선사진(Oblique Transcranial Radiograph)을 이용한 하악전돌증환자의 하악지 시상골절단술후 하악과두위치변화 분석

권대근,이상한,장현중 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.1

This study was intended to evaluate condyle position and the relationship of condyle position change and post surgical relapse following the sagittal split ramus osteotomy for mandible setback in 25 patients by paired t-test and multiple regression analysis. We used oblique transcranial and cephalometric radiographs taken before operation, immediate after operation, and at least 6 months post operatively. 1. In oblique transcranial view, posterior joint space was decreased immediate after operation and increased 6 months after operation. To compare the measurement before and 6 months after operation, there was no statistically significant change in over all joint spaces(P>0.05). 2. The joint spaces changed under the 0.2mm were 30%, 0.2mm to 1.0mm were 60.7%, above 1.0mm were 9.3%. This result reveals that condyle position was relatively reproduced to pre-operative state. 3. Statistically, the amount of mandible set back didn't influence the post operative relapse(P>0.05). 4. Statistically, the amount of mandible set back didn't influence the condylar displacement(P>0.05), and the amount of joint space change didn't influence the post operative relapse.(P>0.05) The changes in joint space is in the standard tracing error or within the adaptive capacity of the individual, it was too small to influence the stability of surgery.

안면비대칭 환자에서 하악의 측방변위와 두개관형태 사이의 연관성

신상욱,이상한,장현중 大韓顎顔面成形再建外科學會 1996 Maxillofacial Plastic Reconstructive Surgery Vol.18 No.4

This study was intended to perform the relationships between mandibualr lateral deviation in facial asymmetry patients and morphology of the cranial vault. In 30 patients(males 14, female 16) using submento-vertical cephalograms that were taken in the pre-operaticve state and posteroanterioir cephalograms that were taken in centric occlusion before, immediate and long term after surgery. 1. Mean mandibular deviation was about - 3.12°and mean of absolute measurement was about 2.50°on the submento-vertical cephalograms. 2. On the submento-vertical cephalograms, there was no significant difference between non-deviation and deviation side but it had tendency that deviation side was larger than non-deviation side on the frontal portion of cranium(Y10 to Y6) and deviation side was samller than non-deviation on the temporal portion of cranium(Y5, Y-1 to Y-5). 3. Mean mandibular deviation was about 1.40°and mean of absolute measurement was about 3.95°on the posteroanterioir cephalograms. 4. There was statistical significance on the influence of surgical change(PT2A-PT1A) to the relapse(PTLA-PT2A)(p<0.05). The more increasing of the change, the more relapse on the posteroanterioir cephalograms. 5. There was no statistical significance on the influence of degree of mandibular deviation to morphology of the cranium on the submento-vertical cephalograms. But it had tendency that the more mandibular deviation, the larger the non-deviation side on the anterior cranium and deviation side on the posterior cranium(p>0.05). 6. There was statistical significance on the influence of the degree of mandibular deviation on the posteroanterioir cephalograms to the difference between non-deviation and deviation side. The more increasing of mandibular deviation, the larger the non-deviation side on the Y4 to Y-6(p<0.05). 7. There was no statistical significance on the influence of difference between non-deviation and deviation side to the relapse on the posteroanterioir cephalograms. But it had tendency that the more increasing of the differece between non-deviation and deviation side, the more increasing the relapse on temporal of cranium.

실사 이미지를 이용한 3D 실감 체험형 분해조ּ립 시뮬레이션 콘텐츠 개발 연구

장현중(Hyeon-Joong Jang),김태겸(Tae-Kyeom Kim),홍성용(Seong-Yong Hong) 한국정보과학회 2015 한국정보과학회 학술발표논문집 Vol.2015 No.6

化膿性 口腔感染에서 嫌氣性細菌의 同定

장현중(Jang Hyun Jung),이상한(Lee Sang Han),변종수(Byun Jong-Soo) 대한구강악안면외과학회 1985 대한구강악안면외과학회지 Vol.11 No.2

In order to determine the prevalence of anaerobic bacteria associated with pyogenic oral infection, the author studied the specimens from twenty patients who visited the Department of Oral Surgery, K.N.U. Hospital during the period from Feb. 1985 to Nov. 1985. In this study, author used GLC (gas liquid chromatography) combined with conventional biochemical method and API-20A system. The result were summarized as follows; The average number of anaerobic bacteria in each specimen was 2.8. Total 56 strains of obligate anaerobes were identified These strains were as follows: Anaerobic gram positive cocci 17 strains (30.4%) Anaerobic gram negative cocci 1 strains (1.8%) Anaerobic gram positive bacilli 11 strains (19.6%) Anaerobic gram negative bacilli 27 strains (48.2%) The most frequent strain was Bacteroides spp. (35.7%) Gas liquid chromatographic (GLC) profiles of cellular fatty acids and metabolic products were useful in identifying Peptococcus spp., Peptostreptococcus spp., Eubacterium spp.

SILICONE TUBE에 삽입된 신경절편이 말초신경 결손부의 재생에 미치는 효과

장현중,박노부,홍창수 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.4

The purpose of this study is to observe the stimulant effect of the isolated nerve segment on the peripheral nerve regeneration using silicone tube in rats. Srague-Dawley female albino rats were used as experimental animals and nerve defects were made by resection of 14 mm-long segment of right sciatic nerves. In control group, the defects were bridged with the silicone tubes. In experimental group, the defects were bridged with the same manner and additionally, 2mm-long nerve segments were inserted at the center of the silicone tubes. 3 months later, the regenerated nerve tissue within the silicone tubes were examined by histologic study. Axonal diameters and numbers of axons were measured and all data were analyzed by using SAS package program. The results obtained were as follows : 1. The experimental group was increased than the control group in general diameters of the regenerated nerve fiber.(P<0.05) 2. The diameters of axons were increased int he experimental group compare to the control group. (P<0.05) 3. The numbers of axons were increased int he experimental group compare to the control group. (P<0.05)

전산화단층촬영법을 이용한 하악전돌증 환자의 외과적 악교정술후 하악과두 위치 변화 검토

이호경,장현중,이상한,Lee, Ho-Kyung,Jang, Hyun-Jung,Lee, Sang-Han 대한악안면성형재건외과학회 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.3

This study was intended to perform the influence of condyle positional change after surgical correction of skeletal Class III malocclusion after orthognathic surgery in 37 patients(male 13, female 24) using computed tomogram that were taken in centric occlusion before, immediate after, and long term after surgery and lateral cephalogram that were taken in centric occlusion before, 7 days within the period of intermaxillary fixation, at the 24 hours later removing intermaxillary fixation and long term after surgery. 1. Mean intercondylar distance was $84.42{\pm}5.30mm$ and horizontal long axis of condylar angle was $12.79{\pm}4.92^{\circ}$ on the right, $13.53{\pm}5.56^{\circ}$ on the left side. Condylar lateral poles were located about 12mm and medial poles about 7mm away from the reference line(AA') on the axial tomogram. Mean intercondylar distance was $83.15{\pm}4.62mm$ and vertical axis angle of condylar angle was $76.28{\pm}428^{\circ}$ on the right, $78.30{\pm}3.79^{\circ}$ on the left. 2. In amount of set back, We found the condylar change(T2C-T1C) which had increasing tendency in group III (amount of setback : 10-15mm). but there was no statistical significance(p>0.05). 3. There was some correlation between condylar change(T2C-T1C) and TMJ dysfunction. It seemed that postoperative condylar change had influenced postoperative TMJ dysfunction, through there was no statistical significance (p>0.05). As we have observed the change of condylar axis in the group that complained of TMJ dysfunction in cases of large amount of mandibular setback. So we consider that the more trying to conserve condylar position will decrease occurrence rate of post operational TMJ dysfunction.

항암제 투여가 이식된 가토 유리자가골의 치유에 미치는 영향

이근호,장현중 慶北大學校 齒科大學 1993 慶北齒大論文集 Vol.10 No.2

저자는 가토 16마리를 사용하여 하악골편을 절제하여 재이식한 후 7일째 대조군 8마리에 생리식염수 5cc를 정주하고 실험군 8마리에 체중 1kg당 Cisplatin 2mg과 5-Fluo- ruracil 40mg을 정주한 후에서 각각 3, 7, 14, 21일째 군별로 2마리씩 희생시켜 이식골의 치유과정을 조직학적으로 비교 관찰하여 다음과 같은 결과를 얻었다. 1. 투약후 3일(이식후 10일)째 이식된 골조직내의 세포는 생활력을 나타내며 골간극에는 신생골주가 형성되었다. 2. 투약후 7일째 형성된 골소주에 의해 수용체와 이식골이 유합되기 시작하여 투약후 14일째 대부분에서 골성유합이 완성되었어며 투약후 21일째에는 재형성과정이 진행되었다. 3. 투약후 각 기간별로 대조군과 실험군에서 명확한 차이는 없었다. The purpose of this study is to investigate the effect of antineoplastic agents on the healing process of free autogenous bone graft to reconstruct mandible immediately after tumor resection. Sixteen rabbits, resected and replanted a part of mandible, were divided into two groups. The eigth experimental rabbits were administrated cisplatin 2mg and 5-fluorouracil 40mg per kg of body weight, and the eight controls were administrated normal saline 5cc on postoperation 7 days. Each of them was sacrified 3,7,14 and 21 days after administration of drugs. Specimens were obtained and processed in a routine manner for H-E stain. After light microscopic examination, following results were obtained. 1. In 3 days after administration of chemotherapic agents, the cell in the graft showed vitality, and new trabecular bone was formed in the gap between host and graft bone. 2. In 7 days after administration, bony union between host bed and graft by new-formed trabecular bone was appeared, and in 14 days achieved almost. In 21 days, remodeling process was appeared. 3. There was no significant difference between experimental and control groups.

Biocoral^�과립 및 탈회상아질의 단독 및 복합매식이 백서악골결손부 회복에 미치는 영향

박성배,장현중,이상한 慶北大學校 齒科大學 1992 慶北齒大論文集 Vol.9 No.1

본 실험은 이소성 골형성능을 지니는 것으로 알려진 0.6N Hcl에 탈회한 상아질편과 다공성 Hydroxyapatite인 Biocoral을 단독 또는 복합 이식하여 골결손부의 골성회복 정도를 비교관찰함으로 골대체물로서의 효용성을 평가하고자 하였다. Sparque-Dawley계 백서 36마리를 탈회상아질 이식군, Biocoral 이식군, 탈회상아질 및 Biocoral 복합 이식군으로 구분하여, 각 실험군백서의 하악골에 직경 0.4㎝ 크기의 반원상 골결손부를 형성하고, 각 이식편을 각 군별로 이식하였다. 술 후 1, 2, 3, 4주에 희생, 실험부를 채취하여, 중성 포르말린에 1일 고정한 후, 5% 질산용액에 1주간 탈회하여, 통법에 따라 H & E 염색 조직 슬라이드를 제작, 광학현미경으로 관찰한 바 다음과 같은 소견을 얻었다. 1. 탈회 상아질편 및 Biocoral 입자들은 실험전기간에 걸쳐 특기할 염증 및 이물 반응을 보이지 않았다. 2. 탈회상아질편 및 Biocoral 입자주위로의 신생골의 직접적인 유합은 술후 2주부터 관찰되었고, 골전도성은 Biocoral 입자가 탈회상아질편에 비해 우수하였다. 3. 신생골에 유합된 탈회상아질편의 골성대치는 Biocoral 입자보다 명확하였으며, 탈회상아질편은 Biocoral 입자와 달리 섬유아세포에 의해 분해흡수되는 양상이었다. 4. 각 군 공히 양호한 골성회복을 이루었으며, 신생골 형성 및 성숙도는 Biocoral 이식군이 타군에 비해 다소 양호하였고, 다음이 탈회상아질 및 Biocoral 복합 이식군 그리고 탈회상아질 이식군 순이었다. 이상의 소견상 탈회상아질 및 Biocoral 입자의 골대체물로서의 우수성이 인정되었으나, 탈회상아질과 Biocoral의 복합 사용이 골결손부회복에 대한 유용한 수단이 될 수 있는지에 대해서는 다각적인 검토가 필요할 것으로 사료되었다. This study was performed to evaluate the efficiency of a single or composite implantation of demineralized dentin and corallin biomaterial (Biocoral) as a bone substitute on bone defect. Implants of demineralized dentin, Biocoral, and demineralized dentin combined with Biocoral were placed in artificial bone defect on mandibles of 36 rats. Animals of each groups were killed at 1, 2, 3 and 4 weeks postimplantion and prepared for light microscopic examination by routine method. the histologic findings were studied with particular attention to new bone formation. The results were summarized as follows: 1. The implanted demineralized dentin chips and Biocoral granules were not showed specific inflammatory and/or foreign reaction through experimental period. 2. The direct new bone deposition around implanted materials was noted from 2 weeks positimplantation in each group. 3. The osteoconduction was more favorable in Biocoral implanted group than in demineralized dentin implanted group, but both implanted materials revealed no osteoinductive evidence. 4. The replacement of demineralized dentin chips by new bone was more evident than Biocoral granules and the implanted demineralized dentin chips were resorbed by action of fibroblast. 5. In general bony healing in each group was good without remarkable difference. But degree of bone formation and its maturity was most favorable in Biocoral implant group and followed by demineralized dentin combined with Biocoral implant group and demineralied dentin implant group in descending order. Above findings reveal that a single or comined implantation of deminralized dentin and Biocoral is favorable on bone defect as a bone substitute. But the efficiency of combined implant of each material is questionable, so it is suggested that more profound studies should be done.

초기설암치료시 예방적 경부곽청술의 의의

김진수,장현중,이상한,홍창수 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.1

The poor survival rates of patients with carcinoma of a tongue, despite of modern therapy, is well recognized. One of the most important prognostic factors is status of the cervical lymph nodes. There have been a long-standing debate about the treatment of cervical lymph nodes in early-stage tongue cancer. There are two major treatment opinion. The one is surgical excision of primary tumor with prophylactic neck dissection, simultaneously, and the other is to delay the cervical therapy until cervical lymph node is palpable. Recently we have experienced the early cervical metastasis in three patients who had been diagnosed as a carcinoma of the tongue. They were T1, T2 lesion and no palpable node was found. But histopathologic examination showed the occult metastasis or delayed cervical metastasis was occured. By the review of literature and clinical experience, we could conclude the prophylactic neck dissection offers a better chance for success than therapeutic neck dissection of palpable lymph nodes, in case of oral tongue cancer.