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Colchicine 복용 후 다장기 부전과 동반되어 발생한 급성 췌장염
장선주 ( Sun Joo Jang ),김경조 ( Kyung Jo Kim ),조민수 ( Min Soo Cho ),박도현 ( Do Hyun Park ),명승재 ( Seung Jae Myung ),양석균 ( Suk Kyun Yang ),김진호 ( Jin Ho Kim ) 대한내과학회 2012 대한내과학회지 Vol.82 No.5
Although intentional colchicine overdose is uncommon, it is a potentially life-threatening condition. Acute pancreatitis due to colchicine overdose has been reported only rarely. A 24-year-old woman ingested 30 tablets of colchicine (a total of 18 mg) with intent to commit suicide. She presented with various clinical features, including gastrointestinal toxicities, acute pancreatitis, electrolyte imbalance, myopathy, bone marrow suppression, and subsequently, hair loss. We report a case of acute pancreatitis due to colchicine intoxication, which was accompanied by various complications; the patient recovered after supportive treatment. In addition to myelosuppression and multiple-organ failure, acute pancreatitis may occur with colchicine intoxication and even worsen after recovery of other manifestations; this has not been reported previously. (Korean J Med 2012;82:599-602)
고혈압 환자의 삶의 질 영향요인 및 측정도구에 대한 체계적 문헌고찰
장선주(Chang, Sun Ju),장선주(Jang, Sun Joo),이승희(Lee, Seung Hee),이현옥(Lee, Hyun Ok) 대한근관절건강학회 2017 근관절건강학회지 Vol.24 No.1
Purpose: The purpose of the study was to comprehensively explore the factors influencing quality of life and its measurements in patients with hypertension. Methods: Based on the PRISMA statement and NECA systematic literature review guideline, a systematic literature review was conducted in this study. To search studies related to quality of life in patients with hypertension, multiple electronic databases were used using a combination of key words hypertension and quality of life. Throughout this process, a total of 983 studies were identified. Then, the second selection processes and quality assessment were conducted by four investigators independently. Finally, a total of 19 studies were included for the analysis. Results: Results showed that quality of life was focused on the health-related quality of life, and the SF-36 was one of the most frequently used measurements. The factors influencing quality of life were categorized into sociodemographic, health-related, health behavioral, and psychosocial variables. Conclusion: Researchers need to consider these multiple factors to promote quality of life in patients with hypertension.


명상 프로그램이 유방암 환자의 파워, 불안, 우울 및 삶의 질에 미치는 효과
장선주 ( Sun Joo Jang ) 한국정신간호학회 2013 정신간호학회지 Vol.22 No.3
Purpose: The purpose of this study was to evaluate the effects of meditation program on power, depression and Quality of Life (QoL) in women with breast cancer. Methods: In this study Barrett`s Power theory derived from Rogers` Unitary Human Being Paradigm was used as a theoretical framework. A randomized controlled design was used with 50 participants recruited and randomly allocated. The experimental group (n=20) received the 8-week meditation program. The control group (n=21) received the same program as the experimental group after completion of the first- and eighth-week questionnaires. Collected data were analyzed using SPSS for Windows. Results: Results of homogeneity verification of preliminary investigation data showed that there were no significant differences between the experimental and control groups except for power scores. Compared with the control group, patients in the meditation treatment group showed significant improvement in scores for power (t=-6.07, p<.001) and QoL (t=-3.45, p=.001), a significant reduction in scores for anxiety (t=2.74, p=.009) and depression (t=2.20, p=.033). Conclusion: The present trial results demonstrate that the 8-week meditation program significantly reduced anxiety and depression, and improved power and QoL in patients with breast cancer. These results suggest that meditation has positive effects on power, emotion and QoL.