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- 저자 : 이주아(Ju-A Lee) (검색결과 48 건)
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피브린 결합능을 가진 합성 펩타이드의 치주인대 세포에 대한 생물학적 영향
이주아,구영,박윤정,구기태,김태일,설양조,이용무,류인철,정종평,Lee, Ju-A,Ku, Young,Park, Yoon-Jeong,Koo, Ki-Tae,Kim, Tae-Il,Seol, Yang-Jo,Lee, Yong-Moo,Rhyu, In-Chul,Chung, Chong-Pyoung 대한치주과학회 2009 Journal of Periodontal & Implant Science Vol.39 No.1
Purpose: Fibronectin(FN), one of the major components of ECM, mediates wide variety of cellular interactions including cell adhesion, migration, proliferation and differentiation. In this study, we used synthetic peptides based on fibrin binding sites of amino-terminal of FN and evaluated their biologic effects on periodontal ligament(PDL) cells. Materials and methods: PDL cells were cultured on synthetic oligopeptides coated dishes and examined for cell adhesion, proliferation via confocal microscope. For detection of ERK1/2, cells were plated and Western blot analysis was performed. Results: PDL cells on synthetic oligopeptide coated dishes showed enhanced cell adhesion and proliferation. Western blot analysis revealed increased level of ERK1/2 phosphorylation in cells plated on FN fragment containing fibrin-binding domain(FF1 and FF5) coated dishes. Conclusion: These results reveals that FN fragment containing fibrin-binding domain possess an enhanced biologic effect of PDL ligament cells.
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사회적 합의 과정을 통한 과학 수업이 과학탐구능력에 미치는 영향
이주아(Lee Ju-A), 백성혜(Paik Seoung-Hey) 한국교원대학교 융합교육연구소 2020 융합교육연구 Vol.6 No.1
This study investigated the effect of science class through social consensus on science exploration ability of 5th graders. The subjects of the study were 5th grade elementary school located in Jeollabuk-do and selected and conducted an experimental group and a control group. In order to ensure maximum homogeneity, a scientific inquiry ability test was conducted as a pretest to confirm that there was no difference between the two groups. The contents of the study were to find out the effect of science class through social consensus and applied it to students as a dissolution and solution unit in the 5th grade of elementary school. As a research method, after selecting an experimental group and a control group, a scientific investigation ability preliminary investigation was conducted. In the experimental group, a total of 10 classes were conducted on five topics that required social consensus, and in the control group, general classes were conducted and compared. As a result of the study, the method of deriving a scientific concept by consensus through a process of multiply analyzing solutions to the topics suggested by teachers and designing appropriate experiments and confirming the results positively affects scientific inquiry ability It was confirmed that it is crazy. In particular, it seems that the results of the relevant exploration ability showed a significant result because the course itself is a process of designing an experiment by setting the hypothesis itself, converting and interpreting data, and generalizing it.
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