KASINICS 광학계의 고스트 분석

이성호,육인수,진호,박수종,한정열,이대희,공경남,조승현,박영식,박장현,한원용,Lee, Sung-Ho,Yuk, In-Soo,Jin, Ho,Pak, Soo-Jong,Han, Jeong-Yeol,Lee, Dae-Hee,Kong, Kyung-Nam,Cho, Seung-Hyun,Park, Young-Sik,Park, Jang-Hyun,Han, Won-Yong 한국천문학회 2005 天文學論叢 Vol.20 No.1

The reimaging optics of the KASINICS (KASI Near Infrared Camera System) includes many transparent components like an entrance window, band-pass filters, and blocking filters. As observational targets or in-field background objects, bright stars may cause optical ghosts that can significantly degrade the system performance of the KASINICS. We estimated analytically the relative brightness of ghost components with respect to a point source and examined the effects of tilting optical components as a method of suppressing ghosts. We also performed numerical ray tracings including all the optical components and found the results are consistent with those of the analytic estimations. We conclude that the KASINICS will not suffer from significant ghost effects with appropriate anti-reflection coatings and fittings for the optical components.

흰쥐의 시상하부외 지역에서의 Growth Hormone Releasing Hormone (GHRH) 유전자발현;뇌하수체내 국부인자로서 Lactotroph분화에 관여할 가능성에 대하여

이성호,Lee, Sung-Ho 대한생식의학회 1996 Clinical and Experimental Reproductive Medicine Vol.23 No.3

Biosynthesis and secretion of anterior pituitary hormones are under the control of specific hypothalamic stimulatory and inhibitory factors. Among them, Growth Hormone Releasing Hormone (GHRH) is the major stimulator of pituitary somatotrophs activating GH gene expression and secretion. Human GHRH is a polypeptide of 44 amino acids initially isolated from pancreatic tumors, and the gene for the hypothalamic form of GHRH is organized into 5 exons spanning over 10 kilobases (kb) on genomic DNA and encodes a messenger RNA of 700-750 nucleotides. Several neuropeptides classically associated with the hypothalamus have been found in the extrahypothalamic regions, suggesting the existence of novel sources, targets and functions. GHRH-like immunoreactivity has been found in several peripheral sites, including placenta, testis, and ovary, indicating that GHRH may also have regulatory roles in peripheral reproductive organs. Furthermore, higher molecular weight forms of the GHRH transcripts were identified from these organs (1.75 kb in testis; 1.75 and >3 kb in ovary). These tissue-specific expression of GHRH gene suggest the existence of unique regulatory mechanism of GHRH expression and function in these organs. In fact, placenta-specific and testis-specific promoters for GHRH transcripts which are located in about 10 kb upstream region of hypothalamic promoter were reported. The use of unique promoters in extrahypothalamic sites could be refered in a different control of GHRH gene and different functions of the translated products in these tissues. Somatotrophs and lactotrophs have been thought to be derived from a common bipotential progenitor, the somatolactotrophs, which give origins to either phenotypes. Although the precise mechanism responsible for the lactotroph differentiation in the anterior pituitary gland has not been yet clalified, there are several candidators for the generation of lactotrophs. In human, the presence of GHRH peptides with different size from authentic hypothalamic form in the normal anterior pituitary and several types of adenoma were demonstrated. Recently our group found the existence of immunoreactive GHRH and its transcript from the normal rat anterior pituitary (gonadotroph> somatotroph> lactotroph), and the GHRH treatment evoked the increased proliferation rate of anterior pituitary cells in vitro. The transgenic mouse models clearly shown that GHRH or NGF overexpression by anterior pituitary cells induced development of pituitary hyperplasia and adenomas particularly GH-oma and prolactinoma. Taken together, we hypothesize that the pituitary GHRH could serve not only as a modulator of hormone secretion but as a paracrine or autocrine regulator of anterior pituitary cell proliferation and differentiation. Interestingly enough, the expression of Pit-1 homeobox gene (the POU class transcription factor) was confined to somatotrophs, lactotrophs and somatolactotrophs in which GHRH receptors are expressed commonly. Concerning the mechanism of somatolactotroph and lactotroph differentiation in the anterior pituitary, we have focused following two possibilities; (1) changes in the relative levels or interactions of both hypothalamic and intrapituitary factors such as dopamine, VIP, somatostatin, NGF and GHRH; (2) alterations of GHRH-GHRH receptor signaling and Pit-1 activity may be the cause of lactotroph differentiation or pituitary hyperplasia and adenoma formation. Extensive further studies will be necessary to solve these complicated questions.

벤처기업의 지식중심문화의 영향에 관한 연구

이성호,Lee, Sung-Ho 한국벤처창업학회 2012 벤처창업연구 Vol.7 No.1

This paper analyzes the relationships between knowledge-centered culture, learning process, and knowledge/learning outcomes. Knowledge management researches have emphasized the important role of a knowledge-centered culture in venture business. After a literature review, research model is developed and the research hypothesis is made. And then, the hypothesis is tested using regression analysis with data collected from venture firms. The results of the empirical study show that cooperative learning does not strengthen the knowledge outcomes on the autonomy and organizational climate of knowledge-centered culture.

원전 이종금속 맞대기용접부 PWSCC 균열건전성평가

이성호,이경수,오창영,Lee, Sung-Ho,Lee, Kyoung-Soo,Oh, Chang-Young 대한기계학회 2012 대한기계학회논문집 Vol.36 No.9

가압경수로형 원전의 Alloy 600 원자로압력용기헤드 관통노즐 및 Alloy 82/182 이종금속 맞대기 용접부에서 일차수응력부식균열(PWSCC)이 보고된 이후 전 세계적으로 PWSCC에 의한 용접부 파단을 예방하기 위해 강화검사를 적용하고 있다. 본 이종금속용접부에 대한 가동중검사에서 균열이 발견된 경우 건전성평가 결과가 도출되기까지 발전소가 정지 상태에 있게 됨에 따라 원전 이용율 저하가 발생할 수 있는데, 이를 예방하기 위해서는 균열건전성평가 관련 기술의 정립뿐만 아니라 신속하게 평가 결과를 도출할 수 있는 시스템의 구축이 필요하다. 본 연구에서는 이종금속 맞대기 용접부를 대상으로 진행하고 있는 PWSCC 균열건전성평가 기준 정립 및 전산 시스템 개발 결과를 제시하였다. 본 연구를 통해 이종금속 맞대기 용접부 PWSCC 균열건전성평가 기술이 정립되고 전산 시스템으로 구현되어 원자로압력용기 주변 이종금속 맞대기 용접부에서의 PWSCC 균열에 대한 기술적 건전성평가 수단을 확보하였다. Primary water stress corrosion cracking (PWSCC) instances have been reported in the Alloy 600 reactor pressure vessel head penetration nozzle and the Alloy 82/182 dissimilar metal butt weld nozzle in several PWRs. Therefore, in-service inspection programs have been adopted worldwide to prevent failure at the weld region. If a PWSCC is observed at the dissimilar metal weld region during inspection, its structural integrity should be evaluated; however, this requires considerable time and effort, and this might lead to a decrease in the plant utilization coefficient. To prevent this, KHNP-CRI have established integrity assessment criteria and developed a computer program for the fast evaluation and judgment of PWSCC. In this paper, the results and current status of the same are presented. Through this study, criteria for the structural integrity evaluation of PWSCC have been established, and a computer program has been developed to realize technical means for the evaluation of PWSCC structural integrity.

진행 위암에서의 위 전절제술에 동반된 원위부 췌-비장 절제

이성호,김욱,송교영,김진조,진형민,박조현,전해명,박승만,안창준,이준현,Lee, Sung-Ho,Kim, Wook,Song, Kyo-Young,Kim, Jin-Jo,Chin, Hyung-Min,Park, Jo-Hyun,Jeon, Hae-Myung,Park, Seung-Man,Ahn, Chang-Jun,Lee, Jun-Hyun 대한위암학회 2007 대한위암학회지 Vol.7 No.2

Purpose: Routine pancreatico-splenectomy with total gastrectomy should no longer be considered as the standard surgical procedure for gastric cancer because of the lack of proven surgical benefit for survival. The aim of this study is to evaluate the clinicopathologic factors and the survival of patients with locally advanced gastric cancer and they had undergone combined pancreatico-splenectomy with a curative intent. Material and Methods: We retrospectively reviewed a total of 118 patients who had undergone total gastrectomy with distal pancreatico-splenectomy from 1990 to 2001. The patients were divided into 2 groups: 90 patients who were free from cancer invasion (group I), and 28 patients with histologically proven cancer invasion into the pancreas (group II). The various clinicopathologic factors that were presumed to influence survival and the survival rates were analyzed. Results: The rate of pathological pancreatic invasion was 23.7%. The tumor stage, depth of invasion, pancreas invasion, lymph node metastasis, lymph node ratio, curability and the hepatic and peritoneal metastasis were statistically significance on univariate analysis. Among these factors, the tumor stage, lymph node ratio and curability were found to be independent prognostic factor on multivariate analysis. The 5-years survival rates were 36.2% for group I and 13.9% for group II. The morbidity rate was 22.1%, and this included pancreatic fistula (5.1%), intra-abdominal abscess (4.2%) and bleeding (4.2%). The overall mortality rate was 0.8%. Conclusion: Combined distal pancreatico-splenectomy with total gastrectomy with a curative intent was selectively indicated for those patients with visible tumor invasion to the pancreas, a difficult complete lymph node dissection around the distal pancreas and spleen, and no evidence of liver metastasis or peritoneal dissemination.

원보 : 공기산화에 의한 중금속이온의 페라이트 생성조건에 관한 연구

이성호,김수생 ( Sung Ho Lee,Soo Saeng Kim ) 한국폐기물자원순환학회 1986 한국폐기물자원순환학회지 Vol.3 No.2

감육배관의 건전성평가 및 정비 관련 기술기준 고찰

이성호,이요섭,김홍덕,이경수,황경모,Lee, Sung Ho,Lee, Yo Seob,Kim, Hong Deok,Lee, Kyoung Soo,Hwang, Kyeong Mo 한국압력기기공학회 2015 한국압력기기공학회 논문집 Vol.11 No.2

Local wall thinning and integrity degradation caused by several mechanisms, such as flow accelerated corrosion, cavitation, flashing and/or liquid droplet impingement, is a main concern in secondary steam cycle piping system of nuclear power plants in terms of safety and operability. Thinned pipe management program (TPMP) has being developed and optimized to reduce the possibility of unplanned shutdown and/or power reduction due to pipe failure caused by wall thinning. In this paper, newest technologies, standards and regulations related to the integrity assessment, repair and replacement of thinned pipe component are reviewed. And technical improvement items in TPMP to secure the reliability and effectiveness are also presented.

나트륨 섭취량 추정을 위한 소변 중 Cl^-의 간이적 측정방법의 유용성 검증

이성호,이채준,주성미,이현주,라왕연,김순옥,Lee, Sung-Ho,Lee, Chae-Joon,Ju, Sung-Mi,Lee, Hyun-Joo,Ra, Wang-Yeon,Kim, Soon-Ok 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.1

The purpose of this study was to measure concentrations of $K^+$, $Na^+$, $Cl^-$ by ionometer with check salt strip, simple salimeter and Ion-selective electrode (ISE) and compare the results of each mensuration; furthermore, the possibility of inferring the $Na^+$ concentration from $Cl^-$ concentration of urine and the impact of $K^+$ on the concentration of each ion was examined. The results showed that ISE determined $Na^+$ and $Cl^-$ concentrations in the urine are highly interrelated (R=0.9039); in addition, concentrations of $Cl^-$, measured with strip and ISE from urine are highly interrelated (R=0.9338). The concentration of $Na^+$ in urine, inferred by measuring $Cl^-$ concentration with strip, has a high relationship (R=0.8580) with the concentration of $Na^+$ in urine, measured by ISE. The results of our study will increase awareness of $Na^+$ intake and the utility of check salt strip, as well as the possibility of inferred $Na^+$ concentration from measures of $Cl^-$ concentration as a screening test for reducing sodium intake.

Zig-Zag 결선 및 Open-Delta 방식을 이용한 새로운 고조파 저감장치의 개발

이성호,김기성,유상봉,Lee, Sung-Ho,Kim, Gi-Sung,Yoo, Sang-Bong 한국조명전기설비학회 2005 조명·전기설비학회논문지 Vol.19 No.1

지금까지의 고조파 필터는 중성선 리액터와 지그재그결선의 영상 고조파 전류를 제거하였으나, 부하율에 따라 고조파 저감율이 변하여 경부하에서는 고조파 저감율이 낮아지는 특성이 있고, 중성선 리액터 과열로 중성선 단선 위험의 문제가 발생하였다. 본 Zig-Zag 결선 및 Open Delta 방식을 이용한 새로운 고조파 저감장치(HANOS)는 Zig-Zag 결선의 Core Block내에 추가로 Open Delta 방식을 결선하여 중성선에 연결함으로써 중성선에 흐르는 영상 고조파 전류가 과열 없이 안전하게 제거되는 것을 시험 분석한 결과로 증명하였다. The conventional harmonic filters to reduce zero harmonic current from neutral reactors and Zig-Zag connection, have several disadvantages of the decreased reduction rate of harmonics under a light load, because they have the load factor-dependent reduction rate of harmonics, and the risk of potential breaking in the neutral line by heated neutral reactor. Based Zig-Zag connection and Open-Delta mode, this new harmonic eliminating device (HANOS) adopts the combination of Zig-Zag connection and Open-Delta mode-the latter is additionally applied to the transformer's core block for connection to the neutral line. The results of this study demonstrated that the new device could eliminate safely zero harmonic current running in the neutral line without heating.

물의 종류에 따른 오미자 추출액의 이화학적 품질특성

이성호,Lee, Sung-Ho 한국식품영양학회 2013 韓國食品營養學會誌 Vol.26 No.4

This is the basic study on the extraction characteristics of Omija (Schizandra chinensis) for juices of Korean traditional foods. Extraction is being performed as 25 times of the solvent ratio at room temperature and at $65^{\circ}C$ with deionized water, tap water and Cheong-song mineral water which have high contents of Ca and Mg. The overall good results of the extraction conditions are calculated from the values of L (Lightness), redness (a), yellowness (b), soluble solids content, acidity, pH levels and the DPPH radical scavenging activity by using the electron donating ability (EDA). The results are as follows: 12 hours of room temperature and 6 hours at $65^{\circ}C$ were good extraction times. The Cheong-song mineral water at $65^{\circ}C$ is available for rapid extractions when compared to deionized water and tap water. A longer extraction time shows lower values of acidity but increasing values of soluble solids content and DPPH radical scavenging activity when using the electron donating ability. The best sequences for the extractions are Cheong-song mineral water followed by tap water and distilled water after overall consideration.