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RISS 인기검색어
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- 저자 : 이봉재 (검색결과 530 건)
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이봉재,김재호,이인철 대한비과학회 1995 Journal of rhinology Vol.2 No.2
Background : The increases of inflammatory cells in the nasal lavages and the mucosal tissues hours after antigen challenge in the allergic rhinitics propose the possibility of the corresponding increase of vascular endothelial adhesion molecules. The purpose the this study is to investigate the effect of allergen challenge on the expression of adhesion molecules and their temporal pattern of expression in the nasal mucosa of allergic rhinitis. Materials and Methods : The inferior turbinate mucosae were taken from 6 patients with perennial allergic rhinitis and cultured in the RPMI 1640 media with relevant antigen(D.farinae) for 0, 1, 2, 4, 6, 12, 24, and 48 hours. The proportion (%) of mucosal vessels expressing endothelial adhesion molecules such as ICAM-1, E-seletin, and VCAM-1 was obtained from the specimens immunostained with ABC-AP method. Results : The expression of E-selectin, with minimal at baseline, was significantly upregulated 1hour after culture with antigen, reached peak at 4 hour (38.3%), and then returned to baseline at 24 hour. The baseline expression of ICAM-1 was most prominent (48%). The incubation of allergic mucosa with antigen increased the ICAM-1 expression slowly until reaching to the peak level (77%) at 12 hour , and the level was maintained as long as 48 hours. Unlike E-selectin or VCAM-1, ICAM-1 was also expressed on the epithelial cells, especially in the basal cell layer. Conclusion : The expression of E-selectin showed a characterisctic of rapid induction and decline in the allergic nasal mucsoa. The prominent expression of ICAM-1 on the epithelial cells as well as on the vascular endothelial cells suggests the active role of ICAM-1 in the extravasation of inflammatory cells and also in the transepithelial migration into the nasal secretion.
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TRIGA Mark-II, III 연구로 시절의 폐로를 위한 시설의 잔류 방사선/능 평가
이봉재,장시영,박승국,정운수,정기정,Lee, B.J.,Chang, S.Y.,Park, S.K.,Jung, W.S.,Jung, K.J. 대한방사선방어학회 1999 방사선방어학회지 Vol.24 No.2
Residual radiation and radioactivity level in TRIGA Mark-II, III research reactors and facilities at the KAERI Seoul site, which are to be decommissioned, have been measured, analyzed and evaluated to know the current status of radiation and radioactivity level and to establish and to provide the technical requirements for the safe decommissioning of the facilities which shall be applied in minimizing the radiation exposure for workers and in preventing the release of the radioactive materials to the environment. Radiation dose rate and surface radioactivity contamination level on the experimental equipments, floors, walls of the facilities, and the surface of the activated materials within the reactor pool structure were measured and evaluated. Radioactivity and radionuclides in the pool and cooling water were also analyzed. In case of the activated reactor pool structures which are very difficult to measure the radiation and radioactivity level, a computer code Fispin was additionally used for estimation of the residual radioactivity and radionuclides. The radiation and radioactivity data obtained in this study were effectively used as basic data for decontamination and dismantling plan for safe decommissioning of TRIGA Mark-II, III facilities.
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실리콘 PIN 다이오드 검출기를 이용한 전자선량계 개발
이봉재,김봉환,장시영,김종수,Lee, B.J.,Kim, B.H.,Chang, S.Y.,Kim, J.S. 대한방사선방어학회 2000 방사선방어학회지 Vol.25 No.4
A prototype electronic dosimeter(PED) adopting a silicon PIN diode detector as a radiation detector has been developed, manufactured and test-evaluated. A radiation signal processing circuit has been electronically tested and then the radiation detection characteristics of this PED has been performance-tested by using a reference photon radiation field. As a result in a electronic performance test, radiation signals from a detector were well observed in the signal processing circuit. The radiation detection sensitivity of this PED after several test-irradiations to $^{137}Cs$ gamma radiation source appeared to be 1.85 cps/$Gy{\cdot}h^{-1}$ with 19.3% of the coefficient of variation, which satisfied the performance criteria for the active personnel radiation monitor. Further improvement of the electronic circuit and operating program will enable the PED to be used in personal monitoring purpose.
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A Case of Hemangiopericytoma Removed with Facial Translocation Approach
이봉재,이재진,조성래 대한비과학회 1996 Journal of rhinology Vol.3 No.1
Hemangiopericytoma, arised from the Zimmerman’s pericyte around capillaries, can develop anywhere there are capillaries in the body. Histopathological diagnosis separating benignancy from malignancy is very difficult and local recurrences after surgery are frequent. Recently we experienced a case of hemangiopeicytoma extending from right skull base to the oral cavity, which developed in 60 year-old man complaining right cheek swelling and intraoral mass persisting for four months. Preoperative histopathologic diagnosis was made with punch biopsy of the gingivobuccal mass. The extent and the vascularity of the tumor were evaluated with computed tomography, magnetic resonance imaging, and angiogram. We could remove the tumor completely via mini lateral facial translocation approach after embolization, so we report the case with brief review of literature.
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반도체 검출기를 이용한 Hybrid 전치증폭기형 전자식 개인선량계 개발
이봉재,김봉환,장시영,김종수,노승용 대한방사선 방어학회 2002 방사선방어학회지 Vol.27 No.1
반도체 검출기를 이용하여 Hybrid 전치증폭기를 갖는 전자식 개인선량계를 설계 제작하고, 방사선 검출 반응특성과 기계적 및 주변 환경 요건에 따른 각종 성능을 평가하였다. ^137Cs 감마 방사선을 이용한 방사선 조사 시험결과 감도는 3.8 cps/Gy·h^-1이고, 10 uSv ∼ 4 Sv 범위의 선량당량 조사시 선량계의 지시값은 오차 8%이하에서 선형성이 잘 유지되었다. 방향의존성은 ±60˚이내에서 4%이하이며 ISO 기준선장에 의한 에너지 반응역역은 60 ∼ 1,250 keV로 나타났으며 IEC, 61526에 의한 선량계의 성능검사시 9개 영역의 시험항목에 대한 국제기준을 만족하였다. An electronic personal dosimeter(EPD) with hybrid type preamplifier adopting a semiconductor detector as a radiation detector has been developed, manufactured and test-evaluated. The radiation detection characteristics of this EPD has been performance-tested by using a reference photon radiation field. After several test-irradiations to a ^137Cs gamma radiation source the radiation detection sensitivity of this EPD appeared to be 3.8 cps/Gy·h^-1, The linearity of radiation response was kept within 8% of the dose equivalent ranges of 10 uSv ∼ 4 Sv and the angular dependence was under less than 4% in angles of ±60˚. It was confirmed that the energy response range was in 60 ∼ 1,250 keV given in the ISO standard. This EPD satisfied the international criteria for the EPD in the mechanical and the environmental performance test for 9 test categories according to IEC 61526.
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